RRC ID 89398
Author Minami A, Onda Y, Shimizu M, Uehara-Yamaguchi Y, Kanatani A, Nakayama R, Toyama K, Takahagi K, Inoue K, Nozoye T, Suzuki M, Kouzai Y, Nomura T, Tanoi K, Endo M, Miki R, Kashihara M, Taoka N, Mochida K.
Title Chelation-based iron uptake mitigates the effects of prolonged high-temperature stress in cool-season grasses.
Journal Nat Commun
Abstract High-temperature stress poses a significant threat to agricultural productivity and ecological diversity. Here, we show the effects of prolonged high-temperature stress on wheat (Triticum aestivum) and the model grass Brachypodium distachyon and demonstrate that heat stress induces iron deficiency in newly emerged leaves. Quantitative trait locus analysis of B. distachyon reveals a genomic region associated with heat resilience that includes the transporter of mugineic acid family phytosiderophores 1 gene (BdTOM1). Iron-deficiency-related genes including BdTOM1 are more highly expressed in a high-temperature-tolerant B. distachyon accession at high temperature than in a sensitive accession, resulting in greater secretion of deoxymugineic acid. Treatment with proline-2'-deoxymugineic acid mitigates heat-induced growth inhibition, but excess iron treatment leads to toxicity in both species. Our findings highlight the role of heat-induced nutritional stress in prolonged high-temperature stress and suggest that iron homeostasis could provide a promising target for improving crop resilience to climate extremes.
Volume 16(1)
Pages 7709
Published 2025-8-28
DOI 10.1038/s41467-025-63005-0
PII 10.1038/s41467-025-63005-0
PMID 40877273
PMC PMC12394411
MeSH Brachypodium* / drug effects Brachypodium* / genetics Brachypodium* / growth & development Brachypodium* / metabolism Brachypodium* / physiology Gene Expression Regulation, Plant Heat-Shock Response* / genetics Hot Temperature Iron* / metabolism Iron Chelating Agents* / pharmacology Plant Leaves / metabolism Plant Proteins / genetics Plant Proteins / metabolism Quantitative Trait Loci / genetics Seasons Stress, Physiological Triticum* / drug effects Triticum* / genetics Triticum* / growth & development Triticum* / metabolism Triticum* / physiology
Resource
Wheat KT020-061