Reference - Detail
| RRC ID | 968 |
|---|---|
| Author | Hirose K, Hashimoto A, Tamura K, Kawamura Y, Ezaki T, Sagara H, Watanabe H. |
| Title | DNA sequence analysis of DNA gyrase and DNA topoisomerase IV quinolone resistance-determining regions of Salmonella enterica serovar Typhi and serovar Paratyphi A. |
| Journal | Antimicrob Agents Chemother |
| Abstract |
The mutations that are responsible for fluoroquinolone resistance in the gyrA, gyrB, parC, and parE genes of Salmonella enterica serovar Typhi and serovar Paratyphi A were investigated. The sequences of the quinolone resistance-determining region of the gyrA gene in clinical isolates which showed decreased susceptibilities to fluoroquinolones had a single mutation at either the Ser-83 or the Asp-87 codon, and no mutations were found in the gyrB, parC, and parE genes. |
| Volume | 46(10) |
| Pages | 3249-52 |
| Published | 2002-10-1 |
| DOI | 10.1128/AAC.46.10.3249-3252.2002 |
| PMID | 12234852 |
| PMC | PMC128770 |
| MeSH | Anti-Infective Agents / pharmacology* DNA Gyrase / genetics* DNA Topoisomerase IV / genetics* Drug Resistance, Bacterial / genetics* Fluoroquinolones Microbial Sensitivity Tests Molecular Sequence Data Mutation Salmonella paratyphi A / drug effects* Salmonella paratyphi A / enzymology Salmonella paratyphi A / genetics Salmonella typhi / drug effects* Salmonella typhi / enzymology Salmonella typhi / genetics Sequence Analysis, DNA |
| IF | 4.904 |
| Times Cited | 74 |
| WOS Category | PHARMACOLOGY & PHARMACY MICROBIOLOGY |
| Altmetric score |
オルトメトリクス指標項目
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| The most frequently cited source | Policy sources |
| Total number of mentions | 3 |
| Altmetric score changes over past 6months | 0.0 |
| Resource | |
| Pathogenic microorganisms | |