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  • Search Condition : Filter (MeSH = AMP-Activated Protein Kinases / genetics)
Species Resource Title
C.elegans tm1978 Glycerol 3-phosphate phosphatase/PGPH-2 counters metabolic stress and promotes healthy aging via a glycogen sensing-AMPK-HLH-30-autophagy axis in C. elegans.
C.elegans tm10766 , tm1944 , tm10677 , tm14007 , tm15233 , tm1856 Germline stem cell integrity and quiescence are controlled by an AMPK-dependent neuronal trafficking pathway.
Mice RBRC01872 Membrane protein CNNM4-dependent Mg2+ efflux suppresses tumor progression.
C.elegans tm1944 , tm1310 , tm1844 Unscheduled epigenetic modifications cause genome instability and sterility through aberrant R-loops following starvation.
Mice RBRC02388 MD2 deficiency prevents high-fat diet-induced AMPK suppression and lipid accumulation through regulating TBK1 in non-alcoholic fatty liver disease.
Human and Animal Cells C2C12(RCB0987) Stilbene analogs of resveratrol improve insulin resistance through activation of AMPK.
Mice RBRC02231 RIPK1 Promotes Energy Sensing by the mTORC1 Pathway.
C.elegans tm1770 Hypodermal responses to protein synthesis inhibition induce systemic developmental arrest and AMPK-dependent survival in Caenorhabditis elegans.
C.elegans tm1944 , tm1231 , tm1941 AMPK blocks starvation-inducible transgenerational defects in Caenorhabditis elegans.
C.elegans tm1944 AMPK and autophagy control embryonic elongation as part of a RhoA-like morphogenic program in nematode.
C.elegans tm1944 Genome-wide RNAi Screen for Fat Regulatory Genes in C. elegans Identifies a Proteostasis-AMPK Axis Critical for Starvation Survival.
C.elegans tm1944 3,3'-Diindolylmethane Suppresses Adipogenesis Using AMPKα-Dependent Mechanism in 3T3-L1 Adipocytes and Caenorhabditis elegans.
C.elegans tm1944 DAF-18/PTEN signals through AAK-1/AMPK to inhibit MPK-1/MAPK in feedback control of germline stem cell proliferation.
C.elegans tm2658 , tm5539 DAF-16/FoxO directly regulates an atypical AMP-activated protein kinase gamma isoform to mediate the effects of insulin/IGF-1 signaling on aging in Caenorhabditis elegans.
Human and Animal Cells HuH-7(RCB1366) Adenosine activates AMPK to phosphorylate Bcl-XL responsible for mitochondrial damage and DIABLO release in HuH-7 cells.
Drosophila P{RS5}CG17273[5-HA-2022] (DGRC#125528) Adenosine nucleotide biosynthesis and AMPK regulate adult life span and mediate the longevity benefit of caloric restriction in flies.
Mice RBRC01294 Rho-kinase inhibition ameliorates metabolic disorders through activation of AMPK pathway in mice.
DNA material pGL4-phSESN2 (RDB07413) Isorhamnetin protects against oxidative stress by activating Nrf2 and inducing the expression of its target genes.
Human and Animal Cells MC3T3-E1(RCB1126) Osteoblast differentiation is functionally associated with decreased AMP kinase activity.
Yeast Genome DNA clones Sip1, a conserved AP-1 accessory protein, is important for Golgi/endosome trafficking in fission yeast.