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  • Search Condition : Filter (MeSH = Alzheimer Disease / metabolism*)
Species Resource
Mice Alzheimer disease-associated peptide, amyloid beta40, inhibits vascular regeneration with induction of endothelial autophagy.
Mice Nrf2 knockout mouse/C57BL6J(RBRC01390) Nrf2 reduces levels of phosphorylated tau protein by inducing autophagy adaptor protein NDP52.
C.elegans tm465 , tm776 REST and stress resistance in ageing and Alzheimer's disease.
DNA material Human ILEI / pcDNA6 (RDB13040) , Human ILEI-siRNA / pSUP (RDB13041). The FAM3 superfamily member ILEI ameliorates Alzheimer's disease-like pathology by destabilizing the penultimate amyloid-β precursor.
Drosophila Dysfunction of different cellular degradation pathways contributes to specific β-amyloid42-induced pathologies.
Mice B6.129-Mapk14<tm1.2Otsu>(RBRC02192) Deficiency of Neuronal p38α MAPK Attenuates Amyloid Pathology in Alzheimer Disease Mouse and Cell Models through Facilitating Lysosomal Degradation of BACE1.
C.elegans tm1779 Insights from Caenorhabditis elegans on the role of metals in neurodegenerative diseases.
Human and Animal Cells MG6(RCB2403) Loss of kallikrein-related peptidase 7 exacerbates amyloid pathology in Alzheimer's disease model mice.
Human and Animal Cells Prostaglandin E2 stimulates the production of amyloid-beta peptides through internalization of the EP4 receptor.
Human and Animal Cells Site-specific aspartic acid isomerization regulates self-assembly and neurotoxicity of amyloid-β.
Human and Animal Cells Amyloid precursor protein beta-secretase (BACE) mRNA expression in human neural cell lines following induction of neuronal differentiation and exposure to cytokines and growth factors.
Human and Animal Cells Eight-residue Abeta peptides inhibit the aggregation and enzymatic activity of Abeta42.
Human and Animal Cells Small heat shock proteins inhibit amyloid-beta protein aggregation and cerebrovascular amyloid-beta protein toxicity.
Human and Animal Cells COS-7(RCB0539) TMEM30A is a candidate interacting partner for the β-carboxyl-terminal fragment of amyloid-β precursor protein in endosomes.