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  • 検索条件 : 絞込み (MeSH = Amyotrophic Lateral Sclerosis* / genetics)
生物種 リソース名 タイトル
ゼブラフィッシュ hspGFFDMC130A, UAS:GFP, UAS:GCaMP7a, SAIGFF213A Dysregulated TDP-43 proteostasis perturbs excitability of spinal motor neurons during brainstem-mediated fictive locomotion in zebrafish.
ヒト・動物細胞 YST-1(RCB2136) Schwann cell derived-peroxiredoxin protects motor neurons against hydrogen peroxide-induced cell death in mouse motor neuron cell line NSC-34.
ヒト・動物細胞 , 遺伝子材料 201B7(HPS0063) , CSII-EF-MCS-IRES2-Venus (RDB04384) , pCMV-VSV-G-RSV-Rev (RDB04393) , pCAG-HIVgp (RDB04394) Monomerization of TDP-43 is a key determinant for inducing TDP-43 pathology in amyotrophic lateral sclerosis.
メダカ OK-Cab (MT830) Optineurin deficiency impairs autophagy to cause interferon beta overproduction and increased survival of mice following viral infection
線虫 tm1287 Targeting the NEDP1 enzyme to ameliorate ALS phenotypes through stress granule disassembly.
ゼブラフィッシュ SAGFF(LF)73 , SAIGFF213A , UAS:mRFP1-TDP-43z , UAS:mRFP1-CRY2olig , UAS:EGFP , mnr2b-hs:Gal4 Optogenetic interrogation of TDP-43 cytotoxicity in a zebrafish ALS model
ショウジョウバエ Loss of amyotrophic lateral sclerosis risk factor SCFD1 causes motor dysfunction in Drosophila.