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  • 検索条件 : 絞込み (MeSH = Anaplastic Lymphoma Kinase)
生物種 リソース名 タイトル
ヒト・動物細胞 Ba/F3(RCB0805) Molecular Mechanisms of Resistance to First- and Second-Generation ALK Inhibitors in ALK-Rearranged Lung Cancer.
ヒト・動物細胞 Ba/F3 Two novel ALK mutations mediate acquired resistance to the next-generation ALK inhibitor alectinib.
ヒト・動物細胞 KU-YS(RCB1318) , SK-N-SH(RCB0426) , TNB1(RCB0481) , KP-N-NS(RCB0687) Activation of anaplastic lymphoma kinase is responsible for hyperphosphorylation of ShcC in neuroblastoma cell lines.
ヒト・動物細胞 IMR-32(RCB1895) NeuroD1 promotes neuroblastoma cell growth by inducing the expression of ALK.
遺伝子材料 CSII-CMV-MCS-IRES2-Bsd (RDB04385) Oncogenic TPM3-ALK activation requires dimerization through the coiled-coil structure of TPM3.
ヒト・動物細胞 WEHI-3B(RCB2853) An Oncogenic ALK Fusion and an RRAS Mutation in KRAS Mutation-Negative Pancreatic Ductal Adenocarcinoma.
ヒト・動物細胞 Ba/F3(RCB0805) CD30 Induces Heat Shock Protein 90 and Signal Integration in Classic Hodgkin Lymphoma Cells.
ヒト・動物細胞 CACO-2(RCB0988) Antitumor activity of the selective ALK inhibitor alectinib in models of intracranial metastases.
ショウジョウバエ The scaffolding protein Cnk binds to the receptor tyrosine kinase Alk to promote visceral founder cell specification in Drosophila.
ヒト・動物細胞 NH-12(RCB2108) Partial deletion of the ALK gene in ALK-positive anaplastic large cell lymphoma.
遺伝子材料 pGL4-phHIF1A (RDB07693) ALK signaling cascade confers multiple advantages to glioblastoma cells through neovascularization and cell proliferation.
ヒト・動物細胞 293T(RCB2202) Novel adaptor protein Shf interacts with ALK receptor and negatively regulates its downstream signals in neuroblastoma.
ヒト・動物細胞 MRC-5 Paracrine receptor activation by microenvironment triggers bypass survival signals and ALK inhibitor resistance in EML4-ALK lung cancer cells.
実験動物マウス RBRC01828 ALK(R1275Q) perturbs extracellular matrix, enhances cell invasion and leads to the development of neuroblastoma in cooperation with MYCN.
ヒト・動物細胞 Ba/F3(RCB0805) Induction of PD-L1 Expression by the EML4-ALK Oncoprotein and Downstream Signaling Pathways in Non-Small Cell Lung Cancer.
ショウジョウバエ NP1131-GAL4 (DGRC#103898) , NP1004-GAL4 (DGRC#112440) and NP2024-GAL4 (DGRC#112749) Anaplastic Lymphoma Kinase Acts in the Drosophila Mushroom Body to Negatively Regulate Sleep.
遺伝子材料 CS-RfA-CG (RDB04390) , pCAG-HIVgp (RDB04394) , pCMV-VSV-G-RSV-Rev (RDB04393). The pleiotrophin-ALK axis is required for tumorigenicity of glioblastoma stem cells.
ヒト・動物細胞 SK-N-SH(RCB0426) ALK receptor tyrosine kinase promotes cell growth and neurite outgrowth.