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  • Search Condition : Filter (MeSH = Anaplastic Lymphoma Kinase)
Species Resource Title
Zebrafish UAS:GFP Alk and Ltk ligands are essential for iridophore development in zebrafish mediated by the receptor tyrosine kinase Ltk.
Human and Animal Cells Ba/F3(RCB0805) Molecular Mechanisms of Resistance to First- and Second-Generation ALK Inhibitors in ALK-Rearranged Lung Cancer.
Human and Animal Cells Ba/F3 Two novel ALK mutations mediate acquired resistance to the next-generation ALK inhibitor alectinib.
Human and Animal Cells KU-YS(RCB1318) , SK-N-SH(RCB0426) , TNB1(RCB0481) , KP-N-NS(RCB0687) Activation of anaplastic lymphoma kinase is responsible for hyperphosphorylation of ShcC in neuroblastoma cell lines.
Human and Animal Cells IMR-32(RCB1895) NeuroD1 promotes neuroblastoma cell growth by inducing the expression of ALK.
DNA material CSII-CMV-MCS-IRES2-Bsd (RDB04385) Oncogenic TPM3-ALK activation requires dimerization through the coiled-coil structure of TPM3.
Human and Animal Cells WEHI-3B(RCB2853) An Oncogenic ALK Fusion and an RRAS Mutation in KRAS Mutation-Negative Pancreatic Ductal Adenocarcinoma.
Human and Animal Cells Ba/F3(RCB0805) CD30 Induces Heat Shock Protein 90 and Signal Integration in Classic Hodgkin Lymphoma Cells.
Human and Animal Cells CACO-2(RCB0988) Antitumor activity of the selective ALK inhibitor alectinib in models of intracranial metastases.
Drosophila The scaffolding protein Cnk binds to the receptor tyrosine kinase Alk to promote visceral founder cell specification in Drosophila.
Human and Animal Cells NH-12(RCB2108) Partial deletion of the ALK gene in ALK-positive anaplastic large cell lymphoma.
DNA material pGL4-phHIF1A (RDB07693) ALK signaling cascade confers multiple advantages to glioblastoma cells through neovascularization and cell proliferation.
Human and Animal Cells 293T(RCB2202) Novel adaptor protein Shf interacts with ALK receptor and negatively regulates its downstream signals in neuroblastoma.
Human and Animal Cells MRC-5 Paracrine receptor activation by microenvironment triggers bypass survival signals and ALK inhibitor resistance in EML4-ALK lung cancer cells.
Mice RBRC01828 ALK(R1275Q) perturbs extracellular matrix, enhances cell invasion and leads to the development of neuroblastoma in cooperation with MYCN.
Human and Animal Cells Ba/F3(RCB0805) Induction of PD-L1 Expression by the EML4-ALK Oncoprotein and Downstream Signaling Pathways in Non-Small Cell Lung Cancer.
Drosophila NP1004-GAL4 (DGRC#112440) and NP2024-GAL4 (DGRC#112749) , NP1131-GAL4 (DGRC#103898) Anaplastic Lymphoma Kinase Acts in the Drosophila Mushroom Body to Negatively Regulate Sleep.
DNA material CS-RfA-CG (RDB04390) , pCAG-HIVgp (RDB04394) , pCMV-VSV-G-RSV-Rev (RDB04393). The pleiotrophin-ALK axis is required for tumorigenicity of glioblastoma stem cells.
Human and Animal Cells SK-N-SH(RCB0426) ALK receptor tyrosine kinase promotes cell growth and neurite outgrowth.