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15 Hits
Search Condition : Filter (MeSH = Chemical and Drug Induced Liver Injury / metabolism)
Species
Resource
RRC ID
Title
Journal
Published
Link
Mice
RBRC01828
80701
The HOIL-1L ligase modulates immune signalling and cell death via monoubiquitination of LUBAC.
Nat Cell Biol
2020-6-1
Pubmed
Full text
Human and Animal Cells
RLC-16(RCB1474)
69215
Ozagrel hydrochloride, a selective thromboxane A₂ synthase inhibitor, alleviates liver injury induced by acetaminophen overdose in mice.
BMC Gastroenterol
2013-1-30
Pubmed
Full text
Human and Animal Cells
HuH-7
67791
Multiple compound-related adverse properties contribute to liver injury caused by endothelin receptor antagonists.
J Pharmacol Exp Ther
2015-2-1
Pubmed
Full text
Zebrafish
Tg(6xTcf/LefBS-miniP:d2EGFP) isi04
66057
Bromodomain and Extraterminal (BET) Proteins Regulate Hepatocyte Proliferation in Hepatocyte-Driven Liver Regeneration.
Am J Pathol
2018-6-1
Pubmed
Full text
Human and Animal Cells
Hepa 1-6(RCB1638)
52265
Mice in the early stage of liver steatosis caused by a high fat diet are resistant to thioacetamide-induced hepatotoxicity and oxidative stress.
Toxicol Lett
2017-8-5
Pubmed
Full text
Human and Animal Cells
THP-1(RCB1189)
45031
Development of a cell-based assay system considering drug metabolism and immune- and inflammatory-related factors for the risk assessment of drug-induced liver injury.
Toxicol Lett
2014-7-3
Pubmed
Full text
Human and Animal Cells
RAW 264(RCB0535)
44327
Pifithrin-α, a pharmacological inhibitor of p53, downregulates lipopolysaccharide-induced nitric oxide production via impairment of the MyD88-independent pathway.
Int Immunopharmacol
2013-4-1
Pubmed
Full text
Human and Animal Cells
THP-1(RCB1189)
43949
Stimulation of human monocytic THP-1 cells by metabolic activation of hepatotoxic drugs.
Drug Metab Pharmacokinet
2012-1-1
Pubmed
Full text
Human and Animal Cells
RAW 264(RCB0535)
43606
Effects of globin digest and its active ingredient Trp-Thr-Gln-Arg on galactosamine/lipopolysaccharide-induced liver injury in ICR mice.
Life Sci
2012-1-30
Pubmed
Full text
Silkworms
36350
Using silkworms to establish alternative animal models for evaluation of drug-induced tissue injury.
Drug Discov Ther
2016-2-1
Pubmed
Full text
Mice
RBRC02975
28085
Liver-specific loss of Atg5 causes persistent activation of Nrf2 and protects against acetaminophen-induced liver injury.
Toxicol Sci
2012-6-1
Pubmed
Full text
Mice
RBRC00806
27914
Activation of autophagy protects against acetaminophen-induced hepatotoxicity.
Hepatology
2012-1-1
Pubmed
Full text
Mice
RBRC01390
12358
Concerted action of sulfiredoxin and peroxiredoxin I protects against alcohol-induced oxidative injury in mouse liver.
Hepatology
2011-3-1
Pubmed
Full text
DNA material
AxCALacZ Adex1CAlacZ (RDB02726)
12187
Hepatoprotective action of adenovirus-transferred HNF-3gamma gene in acute liver injury caused by CCl(4).
FEBS Lett
1999-10-1
Pubmed
Full text
Rats
42
Emergence of different macrophage populations in hepatic fibrosis following thioacetamide-induced acute hepatocyte injury in rats.
J Comp Pathol
2003-1-1
Pubmed
Full text