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  • Search Condition : Filter (MeSH = Chemical and Drug Induced Liver Injury / metabolism)
Species Resource Title
Mice RBRC01828 The HOIL-1L ligase modulates immune signalling and cell death via monoubiquitination of LUBAC.
Human and Animal Cells RLC-16(RCB1474) Ozagrel hydrochloride, a selective thromboxane A₂ synthase inhibitor, alleviates liver injury induced by acetaminophen overdose in mice.
Human and Animal Cells HuH-7 Multiple compound-related adverse properties contribute to liver injury caused by endothelin receptor antagonists.
Zebrafish Tg(6xTcf/LefBS-miniP:d2EGFP) isi04 Bromodomain and Extraterminal (BET) Proteins Regulate Hepatocyte Proliferation in Hepatocyte-Driven Liver Regeneration.
Human and Animal Cells Hepa 1-6(RCB1638) Mice in the early stage of liver steatosis caused by a high fat diet are resistant to thioacetamide-induced hepatotoxicity and oxidative stress.
Human and Animal Cells THP-1(RCB1189) Development of a cell-based assay system considering drug metabolism and immune- and inflammatory-related factors for the risk assessment of drug-induced liver injury.
Human and Animal Cells RAW 264(RCB0535) Pifithrin-α, a pharmacological inhibitor of p53, downregulates lipopolysaccharide-induced nitric oxide production via impairment of the MyD88-independent pathway.
Human and Animal Cells THP-1(RCB1189) Stimulation of human monocytic THP-1 cells by metabolic activation of hepatotoxic drugs.
Human and Animal Cells RAW 264(RCB0535) Effects of globin digest and its active ingredient Trp-Thr-Gln-Arg on galactosamine/lipopolysaccharide-induced liver injury in ICR mice.
Silkworms Using silkworms to establish alternative animal models for evaluation of drug-induced tissue injury.
Mice RBRC02975 Liver-specific loss of Atg5 causes persistent activation of Nrf2 and protects against acetaminophen-induced liver injury.
Mice RBRC00806 Activation of autophagy protects against acetaminophen-induced hepatotoxicity.
Mice RBRC01390 Concerted action of sulfiredoxin and peroxiredoxin I protects against alcohol-induced oxidative injury in mouse liver.
DNA material AxCALacZ Adex1CAlacZ (RDB02726) Hepatoprotective action of adenovirus-transferred HNF-3gamma gene in acute liver injury caused by CCl(4).
Rats Emergence of different macrophage populations in hepatic fibrosis following thioacetamide-induced acute hepatocyte injury in rats.