生物種
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リソース名
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RRC ID
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タイトル
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ジャーナル
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公開日
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外部リンク
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ヒト・動物細胞
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MCR-5
,
Hep G2(RCB1886)
|
72564
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An efficient method for differentiation of human induced pluripotent stem cells into hepatocyte-like cells retaining drug metabolizing activity.
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Drug Metab Pharmacokinet |
2014-1-1 |
Pubmed
Full text
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ヒト・動物細胞
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Hep G2(RCB1648)
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69144
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HepG2-NIAS cells, a new subline of HepG2 cells that can enhance not only CYP3A4 activity but also expression of drug transporters and form bile canaliculus-like networks by the oxygenation culture via a collagen vitrigel membrane.
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J Toxicol Sci |
2022-1-1 |
Pubmed
Full text
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ヒト・動物細胞
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Hep G2(RCB1886)
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67510
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Bioluminescence Measurement of Time-Dependent Dynamic Changes of CYP-Mediated Cytotoxicity in CYP-Expressing Luminescent HepG2 Cells.
|
Int J Mol Sci |
2021-3-11 |
Pubmed
Full text
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遺伝子材料
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pCAGGS (RDB08938)
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65400
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Thalidomide and its metabolite 5-hydroxythalidomide induce teratogenicity via the cereblon neosubstrate PLZF.
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EMBO J |
2021-2-15 |
Pubmed
Full text
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ヒト・動物細胞
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Hep G2(RCB1886)
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63489
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Down-regulation of hepatic CYP3A1 expression in a rat model of indomethacin-induced small intestinal ulcers.
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Biopharm Drug Dispos |
2016-12-1 |
Pubmed
Full text
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ヒト・動物細胞
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293T(RCB2202)
,
Hep G2(RCB1886)
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59836
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Possible involvement of the competition for the transcriptional coactivator glucocorticoid receptor-interacting protein 1 in the inflammatory signal-dependent suppression of PXR-mediated CYP3A induction in vitro.
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Drug Metab Pharmacokinet |
2019-8-1 |
Pubmed
Full text
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ヒト・動物細胞
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Hep G2
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55993
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Acceleration of murine hepatocyte proliferation by imazalil through the activation of nuclear receptor PXR.
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J Toxicol Sci |
2018-1-1 |
Pubmed
Full text
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ヒト・動物細胞
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CACO-2(RCB0988)
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52345
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Parathyroid hormone contributes to the down-regulation of cytochrome P450 3A through the cAMP/PI3K/PKC/PKA/NF-κB signaling pathway in secondary hyperparathyroidism.
|
Biochem Pharmacol |
2017-12-1 |
Pubmed
Full text
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ヒト・動物細胞
|
HSC-2(RCB1945)
,
HSC-3(RCB1975)
,
HSC-4(RCB1902)
|
52279
|
Evaluation of Biological Activity of Mastic Extracts Based on Chemotherapeutic Indices.
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In Vivo |
2017-1-1 |
Pubmed
Full text
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ヒト・動物細胞
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Hep G2
,
HuH-7
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45077
|
Retinoid X receptor α in human liver is regulated by miR-34a.
|
Biochem Pharmacol |
2014-7-15 |
Pubmed
Full text
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ヒト・動物細胞
|
Hep G2
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44160
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Inhibition of CYP3A4 by 6',7'-dihydroxybergamottin in human CYP3A4 over-expressed hepG2 cells.
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J Pharm Pharmacol |
2012-12-1 |
Pubmed
Full text
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ヒト・動物細胞
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CV-1(RCB0160)
,
Hep G2
|
44049
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Identification of endocrine disrupting chemicals activating SXR-mediated transactivation of CYP3A and CYP7A1.
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Mol Cell Endocrinol |
2013-1-5 |
Pubmed
Full text
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ヒト・動物細胞
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THP-1(RCB1189)
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43949
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Stimulation of human monocytic THP-1 cells by metabolic activation of hepatotoxic drugs.
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Drug Metab Pharmacokinet |
2012-1-1 |
Pubmed
Full text
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ヒト・動物細胞
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Hep G2
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43692
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Tocotrienol attenuates triglyceride accumulation in HepG2 cells and F344 rats.
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Lipids |
2012-5-1 |
Pubmed
Full text
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ヒト・動物細胞
|
Hep G2
,
HuH-7(RCB1366)
|
43270
|
Post-transcriptional regulation of human pregnane X receptor by micro-RNA affects the expression of cytochrome P450 3A4.
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J Biol Chem |
2008-4-11 |
Pubmed
Full text
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ヒト・動物細胞
|
CACO-2(RCB0988)
|
38246
|
Induction of UGT1A1 and CYP2B6 by an antimitogenic factor in HepG2 cells is mediated through suppression of cyclin-dependent kinase 2 activity: cell cycle-dependent expression.
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Drug Metab Dispos |
2010-1-1 |
Pubmed
Full text
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ヒト・動物細胞
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NIH3T3
,
Hep G2
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38134
|
Cell-sized condensed collagen microparticles for preparing microengineered composite spheroids of primary hepatocytes.
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Lab Chip |
2015-10-7 |
Pubmed
Full text
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ヒト・動物細胞
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201B7(HPS0063)
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36862
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An Optimal Medium Supplementation Regimen for Initiation of Hepatocyte Differentiation in Human Induced Pluripotent Stem Cells.
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J Cell Biochem |
2015-8-1 |
Pubmed
Full text
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