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Species Resource Title
Human and Animal Cells HuH-7(RCB1366) Dual inhibition of DNA-PK and Polϴ boosts precision of diverse prime editing systems.
C.elegans tm1145 , tm1524 , tm2026 Inheritance of paternal DNA damage by histone-mediated repair restriction.
C.elegans tm2026 BRCA1-associated structural variations are a consequence of polymerase theta-mediated end-joining.
C.elegans tm1842 , tm2572 Hypersensitivity to DNA double-strand breaks associated with PARG deficiency is suppressed by exo-1 and polq-1 mutations in Caenorhabditis elegans.
C.elegans tm2026 , tm1298 Genomic Scars Generated by Polymerase Theta Reveal the Versatile Mechanism of Alternative End-Joining.
C.elegans tm2572 Single-nucleotide base excision repair DNA polymerase activity in C. elegans in the absence of DNA polymerase β.
C.elegans tm2026 Polymerase theta-mediated end joining of replication-associated DNA breaks in C. elegans.
C.elegans tm2572 , tm2606 , tm2026 , tm1145 A Polymerase Theta-dependent repair pathway suppresses extensive genomic instability at endogenous G4 DNA sites.
C.elegans tm2073 , tm1145 , tm1842 , tm2026 Polymerase Θ is a key driver of genome evolution and of CRISPR/Cas9-mediated mutagenesis.
C.elegans tm2026 , tm2171 , tm2134 , tm1145 , tm1298 , tm2134 Caenorhabditis elegans POLQ-1 and HEL-308 function in two distinct DNA interstrand cross-link repair pathways.