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Species Resource Title
Drosophila Artificial competition shows the replicative superiority of KP elements over complete P elements in Drosophila melanogaster and D. simulans.
DNA material tFucci(CA)2/pCSII-EF (RDB15446) Mammalian H4K16ac regulates the spatiotemporal order of genome replication rather than gene expression.
Prokaryotes E. coli ME10091 A single-molecule approach to DNA replication in Escherichia coli cells demonstrated that DNA polymerase III is a major determinant of fork speed.
Drosophila 7288R-1 , 14884R-1 USP8 and Hsp70 regulate endoreplication by synergistically promoting Fzr deubiquitination and stabilization.
DNA material CSII-CMV-MCS-IRES2-Bsd (RDB04385) Polyubiquitinated PCNA triggers SLX4-mediated break-induced replication in alternative lengthening of telomeres (ALT) cancer cells.
Yeast FY21311 Replication stress response in fission yeast differentially depends on maintaining proper levels of Srs2 helicase and Rrp1, Rrp2 DNA translocases.
DNA material CSIV-TRE-RfA-UbC-KT (RDB12878) The ribonuclease domain function is dispensable for SLFN11 to mediate cell fate decision during replication stress response.
C.elegans tm598 LONP-1 and ATFS-1 sustain deleterious heteroplasmy by promoting mtDNA replication in dysfunctional mitochondria.
C.elegans tm6658 , tm544 , tm6724 USP7 and VCPFAF1 define the SUMO/Ubiquitin landscape at the DNA replication fork.
Yeast BY28997(YST1351) , BY28998(YST1400) , BY28266(YST2199) , BY28999(YST2204) , BY29000(YST2211) , BY29001(YST2359) , BY28267(YST2363) , BY28270(YST2393) , BY28271(YST2395) , BY28273(YST2397) Pre-initiation complex assembly functions as a molecular switch that splits the Mcm2-7 double hexamer.
Yeast pNHK53, pMK152 Multiple signaling kinases target Mrc1 to prevent genomic instability triggered by transcription-replication conflicts.
Yeast FY13012(TK7) RecQ DNA Helicase Rqh1 Promotes Rad3ATR Kinase Signaling in the DNA Replication Checkpoint Pathway of Fission Yeast.
Yeast FY11064(MY3141) , FY10067(MY2167) Expression of the cancer-associated DNA polymerase ε P286R in fission yeast leads to translesion synthesis polymerase dependent hypermutation and defective DNA replication.
DNA material pdeltaBN.AR1 (RDB18705) Amplification of plasmids containing a mammalian replication initiation region is mediated by controllable conflict between replication and transcription.
DNA material pG5 (RDB18709) Dissection of the beta-globin replication-initiation region reveals specific requirements for replicator elements during gene amplification.
DNA material pC12 (RDB18710) , pD8 (RDB18711) Dissection of mammalian replicators by a novel plasmid stability assay.
C.elegans tm2026 , tm1524 , tm202 RPA complexes in Caenorhabditis elegans meiosis; unique roles in replication, meiotic recombination and apoptosis.
C.elegans tmC18 Identification of the critical replication targets of CDK reveals direct regulation of replication initiation factors by the embryo polarity machinery in C. elegans.
Human and Animal Cells Ehrlich(RCB0142) , FM3A(RCB0086) , V79(RCB0008) Mouse DNA primase plays the principal role in determination of permissiveness for polyomavirus DNA replication.
Human and Animal Cells 293(RCB1637) CTF18 interacts with replication protein A in response to replication stress.