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  • 検索条件 : 絞込み (MeSH = DNA-Binding Proteins* / genetics)
生物種 リソース名 タイトル
原核生物(大腸菌) Involvement of the inner surface residues of bacterial SMC protein MukB in the ssDNA binding in vitro.
実験動物マウス RBRC01828 PTIP epigenetically regulates DNA damage-induced cell cycle arrest by upregulating PRDM1.
ミヤコグサ・ダイズ MG-20 The root nodule symbiosis regulator NIN exhibits broad DNA binding specificity conferred by an NLP-inherited motif.
線虫 tm4439 , tm985 TDP-43 proteinopathies and neurodegeneration: insights from Caenorhabditis elegans models.
線虫 tm1817 , tmC25 , tmIs1241 Protein sequence editing defines distinct and overlapping functions of SKN-1A/Nrf1 and SKN-1C/Nrf2.
線虫 tm1779 6-PPD induces mitochondrial dysfunction and reduces healthspan and lifespan through SKN-1 in Caenorhabditis elegans.
遺伝子材料 pCAGGS (RDB08938) , pCMV-VSV-G-RSV-Rev (RDB04393) , pCAG-HIVgp (RDB04394) , CSII-CMV-MCS-IRES2-Bsd (RDB04385) An interactome-based framework for DDB1- and CUL4-associated factor prioritization in targeted protein degradation.
ショウジョウバエ DGRC#104978 , DGRC#150336 ETS transcription factor pointed controls germline survival in Drosophila.
ショウジョウバエ DGRC#118177 , DGRC#118616 MYCBP interacts with Sakura and Otu and is essential for germline stem cell renewal and differentiation and oogenesis.
ゼブラフィッシュ UAS:GFP-LC3-RFP-LC3∆G, SAGFF(LF)73A, SAIGFF213A, mnr2b-hs:Gal4, TDP-43DKO, UAS:hmCP2AGd410mT436A, UAS:mCherry-P2A-EGFP-d410m-T436A Intrinsically accelerated cellular degradation is amplified by TDP-43 loss in ALS-vulnerable motor neurons in a zebrafish model.
ゼブラフィッシュ mnr2b-hs:opTDP-43h, mnr2b-hs:EGFP-TDP43z Biallelic variants in DNAJC7 cause familial amyotrophic lateral sclerosis with the TDP-43 pathology.
ショウジョウバエ D. simulans The Piwi-piRNA complex initiates transposon silencing via transcription termination factors PNUTS and Senataxin.
酵母 FY19706 Mutual, spatially limited control of meiotic DNA break formation by Mre11-Rad50-Nbs1 DNA repair complex and Tel1 (ATM) protein kinase.
酵母 FY9897 , FY14415 , FY39926 Metal ion homeostasis regulates condensin-dependent chromatin architecture and chromosome segregation in Schizosaccharomyces pombe.
ヒト・動物細胞 TE-6(RCB1950) Zinc Finger Protein 82 regulates p53 protein stability through histone deacetylase and enhances neo-adjuvant chemotherapy in esophageal cancer.
ヒト・動物細胞 , 遺伝子材料 293(RCB1637) , Achilles/pRSETB (RDB15982) , B6N Mouse BAC clone B6Ng01-222C01 , pCAG-Achilles-Tardbp 3' UTR (RDB21123) , pCAG-Achilles-Tardbp deltaUTR (RDB21124) , pCMV-TARDBP-pA (RDB21125) A partial deletion of the Tardbp 3´UTR affects TDP-43 regulation and leads to motor dysfunction in mice.
遺伝子材料 pGFP-C220 (RDB20681) , pGFP-C233 (RDB20682) , pGFP-C243 (RDB20683) , pGFP-C253 (RDB20684) , pGFP-C263 (RDB20685) , pGFP-C274 (RDB20686) , pGFP-F220 (RDB20687) , pGFP-RRM2 (RDB20688) , pRFP-C220 (RDB20689) , pGFP-C220Δ (RDB20690) , ... Hetero-oligomerization of TDP-43 carboxy-terminal fragments with cellular proteins contributes to proteotoxicity.
線虫 tm1502 A multiparametric anti-aging CRISPR screen uncovers a role for BAF in protein synthesis regulation.
線虫 tm3410 , tm515 , tm1978 , tm2318 , tm3262 Regulatory mechanism of cold-inducible diapause in Caenorhabditis elegans.
線虫 tm6360 , tm2842 , tm3886 , tm1682 , tm1670 Persistent TFIIH binding to non-excised DNA damage causes cell and developmental failure.