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Zebrafish SAG4A Downregulation of stanniocalcin 1 is responsible for sorafenib-induced cardiotoxicity.
Human and Animal Cells A549(RCB0098) Plasma-activated medium ameliorates the chemoresistance of human lung adenocarcinoma cells mediated via downregulation of claudin-2 expression.
Human and Animal Cells 293T(RCB2202) miR-709 exerts an angiogenic effect through a FGF2 upregulation induced by a GSK3B downregulation.
Algae NIES-843 Down-regulation of iron/zinc ion transport and toxin synthesis in Microcystis aeruginosa exposed to 5,4'-dihydroxyflavone.
Drosophila Presynaptic Ube3a E3 ligase promotes synapse elimination through down-regulation of BMP signaling.
Human and Animal Cells LNCap.FGC(RCB2145) , PC-3(RCB2145) Down-Regulation of CYP3A4 by the KCa1.1 Inhibition Is Responsible for Overcoming Resistance to Doxorubicin in Cancer Spheroid Models.
Human and Animal Cells MKN7(RCB0999) Down-regulation of stimulator of interferon genes (STING) expression and CD8+ T-cell infiltration depending on HER2 heterogeneity in HER2-positive gastric cancer.
Human and Animal Cells HSC-3(RCB1975) Inhibition of TGF-beta1 suppresses motility and invasiveness of oral squamous cell carcinoma cell lines via modulation of integrins and down-regulation of matrix-metalloproteinases.
Human and Animal Cells THP-1(RCB1189) Downregulation of osteoprotegerin in colorectal cancer cells promotes liver metastasis via activating tumor-associated macrophage.
Human and Animal Cells HUDEP-2(RCB4557) Coordinated β-globin expression and α2-globin reduction in a multiplex lentiviral gene therapy vector for β-thalassemia.
Human and Animal Cells Saos-2(RCB0428) Downregulation of matrix metalloproteinase-9 mRNA by valproic acid plays a role in inhibiting the shedding of MHC class I-related molecules A and B on the surface of human osteosarcoma cells.
Mice RBRC00144 Impaired Repopulating Ability of Uhrf2-/- Hematopoietic Progenitor Cells in Mice.
Human and Animal Cells C2C12(RCB0987) Platinum-based anticancer drugs-induced downregulation of myosin heavy chain isoforms in skeletal muscle of mouse.
Human and Animal Cells A549 Downregulation of angulin-1/LSR induces malignancy via upregulation of EGF-dependent claudin-2 and TGF-β-dependent cell metabolism in human lung adenocarcinoma A549 cells.
Human and Animal Cells PC-3(RCB2145) Downregulation of IL-8 and IL-10 by the Activation of Ca2+-Activated K+ Channel KCa3.1 in THP-1-Derived M2 Macrophages.
Human and Animal Cells B16F10(RCB2630) New Butyroside D from Argan Press Cake Possess Anti-Melanogenesis Effect via MITF Downregulation in B16F10 and HEM Cells.
Silkworms n03 , p50 Masculinizer-induced dosage compensation is achieved by transcriptional downregulation of both copies of Z-linked genes in the silkworm, Bombyx mori.
Human and Animal Cells G-361(RCB0991) G3139 induces cell death by caspase-dependent and -independent apoptosis on human melanoma cell lines.
Human and Animal Cells Hep G2 , HeLa(RCB0007) Hepatitis C virus core protein inhibits apoptosis via enhanced Bcl-xL expression.
Human and Animal Cells MDCK(RCB0995) Down-regulation of Mcl-1 by inhibition of the PI3-K/Akt pathway is required for cell shrinkage-dependent cell death.