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Species Resource Title
Mice RBRC01390 Nrf2 downregulates zymosan-induced neutrophil activation and modulates migration.
Human and Animal Cells P19.CL6(RCB2318) Downregulation of the Cd38-Cyclic ADP-Ribose Signaling in Cardiomyocytes by Intermittent Hypoxia via Pten Upregulation.
Human and Animal Cells HuCCT1(RCB1960) , RBE(RCB1292) METTL3-mediated m6A methylation on lncRNA H19 inhibits intrahepatic cholangiocarcinoma progression through PPARγ downregulation.
Human and Animal Cells TE-5(RCB1949) , TE-4(RCB2097) , TE-8(RCB2098) , TE-11(RCB2100) miR‑100‑5p and miR‑203a‑3p suppress esophageal squamous cell carcinoma progression by targeting FKBP5.
Drosophila 15390R-2 , 14941R-2 , 4236R-1 , 3114R-2 , 9809R-1 Impaired mitochondria-initiated crosstalk with lysosomes reciprocally aggravates mitochondrial defect through LManVI.
Pathogenic bacteria Vibrio parahaemolyticus Down-Regulates the Intracellular c-di-GMP Level to Promote Swarming Motility by Sensing Surface.
Human and Animal Cells HCT116(RCB2979) Downregulation of cGAS/STING expression in tumor cells by cancer-associated fibroblasts in colorectal cancer.
Human and Animal Cells CACO-2(RCB0988) Apple-derived extracellular vesicles modulate the expression of human intestinal bile acid transporter ASBT/SLC10A2 via downregulation of transcription factor RARα.
Zebrafish SAG4A Downregulation of stanniocalcin 1 is responsible for sorafenib-induced cardiotoxicity.
Human and Animal Cells A549(RCB0098) Plasma-activated medium ameliorates the chemoresistance of human lung adenocarcinoma cells mediated via downregulation of claudin-2 expression.
Human and Animal Cells 293T(RCB2202) miR-709 exerts an angiogenic effect through a FGF2 upregulation induced by a GSK3B downregulation.
Algae NIES-843 Down-regulation of iron/zinc ion transport and toxin synthesis in Microcystis aeruginosa exposed to 5,4'-dihydroxyflavone.
Drosophila Presynaptic Ube3a E3 ligase promotes synapse elimination through down-regulation of BMP signaling.
Human and Animal Cells LNCap.FGC(RCB2145) , PC-3(RCB2145) Down-Regulation of CYP3A4 by the KCa1.1 Inhibition Is Responsible for Overcoming Resistance to Doxorubicin in Cancer Spheroid Models.
Human and Animal Cells KG-1a(RCB1928) , HL-60 MYCT-1 Gene Expression in Patients with Gastric Cancer: an Ex Vivo Study.
Human and Animal Cells MKN7(RCB0999) Down-regulation of stimulator of interferon genes (STING) expression and CD8+ T-cell infiltration depending on HER2 heterogeneity in HER2-positive gastric cancer.
Human and Animal Cells HSC-3(RCB1975) Inhibition of TGF-beta1 suppresses motility and invasiveness of oral squamous cell carcinoma cell lines via modulation of integrins and down-regulation of matrix-metalloproteinases.
Human and Animal Cells THP-1(RCB1189) Downregulation of osteoprotegerin in colorectal cancer cells promotes liver metastasis via activating tumor-associated macrophage.
Human and Animal Cells HUDEP-2(RCB4557) Coordinated β-globin expression and α2-globin reduction in a multiplex lentiviral gene therapy vector for β-thalassemia.
Human and Animal Cells Saos-2(RCB0428) Downregulation of matrix metalloproteinase-9 mRNA by valproic acid plays a role in inhibiting the shedding of MHC class I-related molecules A and B on the surface of human osteosarcoma cells.