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  • Search Condition : Filter (MeSH = Down-Regulation)
Species Resource
DNA material AxCANCre (RDB01748) Ribozymes targeting serine/threonine kinase Akt1 sensitize cells to anticancer drugs.
DNA material P450 2B1 (CYP2B1) cDNA (RDB01245) Impaired nuclear translocation of CAR in hepatic preneoplastic lesions: association with an attenuated CYP2B induction by phenobarbital.
DNA material pCALwL (RDB01679) Developmental alteration of nerve injury induced glial cell line-derived neurotrophic factor (GDNF) receptor expression is crucial for the determination of injured motoneuron fate.
DNA material AxCANCre (RDB01748) , pCALNL5 (RDB01862). TGFbeta3-induced activation of RhoA/Rho-kinase pathway is necessary but not sufficient for epithelio-mesenchymal transdifferentiation: implications for palatogenesis.
Yeast BY21468 (=YPH500) , BY22813 (=CMY765) The yeast ubiquitin ligase Rsp5 downregulates the alpha subunit of nascent polypeptide-associated complex Egd2 under stress conditions.
DNA material AxCANCre (RDB01748) Accelerated degradation of cellular FLIP protein through the ubiquitin-proteasome pathway in p53-mediated apoptosis of human cancer cells.
C.elegans tm1954 Genomic clusters, putative pathogen recognition molecules, and antimicrobial genes are induced by infection of C. elegans with M. nematophilum.
C.elegans cDNA? Cell cycle progression requires the CDC-48UFD-1/NPL-4 complex for efficient DNA replication.
C.elegans tm1267 , tm629 Semaphorin controls epidermal morphogenesis by stimulating mRNA translation via eIF2alpha in Caenorhabditis elegans.
C.intestinalis / (O.japonicus) Wild C.int Novel genes involved in canonical Wnt/beta-catenin signaling pathway in early Ciona intestinalis embryos.
Prokaryotes E. coli Keio collection Protection of the glutamate pool concentration in enteric bacteria.
Arabidopsis / Cultured plant cells, genes pst16228 Regulation of the anthocyanin biosynthetic pathway by the TTG1/bHLH/Myb transcriptional complex in Arabidopsis seedlings.
Arabidopsis / Cultured plant cells, genes rpc00035  Why does anatabine, but not nicotine, accumulate in jasmonate-elicited cultured tobacco BY-2 cells?
C.elegans tm2949 MVB-12, a fourth subunit of metazoan ESCRT-I, functions in receptor downregulation.
Prokaryotes E. coli MC4100 , MG1655 , W3110 , JW2514 , JW1670 , JW2781 The iscS gene deficiency affects the expression of pyrimidine metabolism genes.
Drosophila Downregulation of Notch mediates the seamless transition of individual Drosophila neuroepithelial progenitors into optic medullar neuroblasts during prolonged G1.
Mice Xist1loxGFPmice Impeding Xist expression from the active X chromosome improves mouse somatic cell nuclear transfer.
DNA material H3001F04 (MCH000524) , H3007A09 (MCH002809) , H3010A01 (MCH004001) , H3015C08 (MCH006056) , H3015F09 (MCH006129) , H3016D10 (MCH006482) , H3023C07 (MCH009255) , H3023C08 (MCH009256) , H3024A07 (MCH009607) , H3026A08 (MCH010408) , ... Immediate early genes of glucocorticoid action on the developing intestine.
DNA material AxCANLacZ (RDB03211) Analysis of gene expression profile induced by hepatocyte nuclear factor 4alpha in hepatoma cells using an oligonucleotide microarray.
Mice Map2k4 knockout mice Hepatoblasts comprise a niche for fetal liver erythropoiesis through cytokine production.