生物種
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リソース名
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RRC ID
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タイトル
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ジャーナル
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公開日
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外部リンク
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ヒト・動物細胞
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HCE-T(RCB2280)
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71863
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Discovery of Novel TRPM8 Blockers Suitable for the Treatment of Somatic and Ocular Painful Conditions: A Journey through pKa and LogD Modulation.
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J Med Chem |
2021-11-25 |
Pubmed
Full text
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ヒト・動物細胞
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PANC-1(RCB2095)
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69557
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Structure-activity relationship and mechanistic study on guggulsterone derivatives; Discovery of new anti-pancreatic cancer candidate.
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Bioorg Med Chem |
2022-1-15 |
Pubmed
Full text
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ヒト・動物細胞
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Lu99(RCB1900)
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67417
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Discovery of imidazo[1,2-b]pyridazine derivatives: selective and orally available Mps1 (TTK) kinase inhibitors exhibiting remarkable antiproliferative activity.
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J Med Chem |
2015-2-26 |
Pubmed
Full text
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ヒト・動物細胞
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CACO-2(RCB0988)
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293T(RCB2202)
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66241
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MRC5 cells engineered to express ACE2 serve as a model system for the discovery of antivirals targeting SARS-CoV-2.
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Sci Rep |
2021-3-8 |
Pubmed
Full text
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ヒト・動物細胞
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Ba/F3
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65071
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Discovery and Pharmacological Characterization of JNJ-42756493 (Erdafitinib), a Functionally Selective Small-Molecule FGFR Family Inhibitor.
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Mol Cancer Ther |
2017-6-1 |
Pubmed
Full text
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ヒト・動物細胞
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PC-9(RCB4455)
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65019
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Discovery of 1-{(3R,4R)-3-[({5-Chloro-2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)methyl]-4-methoxypyrrolidin-1-yl}prop-2-en-1-one (PF-06459988), a Potent, WT Sparing, Irreversible Inhibitor of T790M-Containing EGFR Mutants.
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J Med Chem |
2016-3-10 |
Pubmed
Full text
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ヒト・動物細胞
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KP4(RCB1005)
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64303
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Discovery of amivantamab (JNJ-61186372), a bispecific antibody targeting EGFR and MET.
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J Biol Chem |
2021-1-1 |
Pubmed
Full text
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ヒト・動物細胞
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HuCCT1(RCB1960)
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63250
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Discovery of a chemical compound that suppresses expression of BEX2, a dormant cancer stem cell-related protein.
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Biochem Biophys Res Commun |
2021-1-22 |
Pubmed
Full text
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ヒト・動物細胞
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5637(RCB1191)
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59646
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Discovering simple phenylboronic acid and benzoxaborole derivatives for experimental oncology - phase cycle-specific inducers of apoptosis in A2780 ovarian cancer cells.
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Invest New Drugs |
2019-2-1 |
Pubmed
Full text
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ヒト・動物細胞
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MCF7(RCB1904)
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58578
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Discovery of gamma-mangostin from Garcinia mangostana as a potent and selective natural SIRT2 inhibitor.
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Bioorg Chem |
2020-1-1 |
Pubmed
Full text
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ヒト・動物細胞
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ATN-1(RCB1440)
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57814
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Jietacins, azoxy natural products, as novel NF-κB inhibitors: Discovery, synthesis, biological activity, and mode of action.
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Eur J Med Chem |
2019-9-15 |
Pubmed
Full text
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カイコ
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56922
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[The Usefulness of Silkworms as a Model Animal for Evaluating the Effectiveness of Medicine and Food].
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Yakugaku Zasshi |
2017-1-1 |
Pubmed
Full text
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カイコ
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36366
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Studies of host-pathogen interactions and immune-related drug development using the silkworm: interdisciplinary immunology, microbiology, and pharmacology studies.
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Drug Discov Ther |
2015-8-1 |
Pubmed
Full text
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カイコ
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36363
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Current use of silkworm larvae (Bombyx mori) as an animal model in pharmaco-medical research.
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Drug Discov Ther |
2015-4-1 |
Pubmed
Full text
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遺伝子材料
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Nano-lantern clones: pYNL-N1 (RDB13323)
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pYNL-C1 (RDB13324)
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pCNL-N1 (RDB13325)
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pCNL-C1 (RDB13326)
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pONL-N1 (RDB13327)
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pONL-C1 (RDB13328)
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pYNL-N1_Mito (RDB13329)
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pCNL-N1_Mito (RDB13330)
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pONL-N1_Mito (RDB13331)
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pYNL-N1_3xNLS (RDB13332)
,
...
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35939
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Recent progress in luminescent proteins development.
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Curr Opin Chem Biol |
2015-8-1 |
Pubmed
Full text
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カイコ
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22800
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[Identification of novel therapeutically effective antibiotics using silkworm infection model].
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Yakugaku Zasshi |
2012-1-1 |
Pubmed
Full text
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