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  • 検索条件 : 絞込み (MeSH = GTPase-Activating Proteins / genetics)
生物種 リソース名 タイトル
遺伝子材料 pcDNA3-hARFGAP1-HA (RDB20104) , pcDNA3-hARFGAP2-HA (RDB20105) , pcDNA3-hARFGAP3-HA (RDB20106) , EGFP-VSVG-KDELR2 (RDB20107) Three homologous ArfGAPs participate in coat protein I-mediated transport.
線虫 tm2241 The Rab GTPase activating protein TBC-2 regulates endosomal localization of DAF-16 FOXO and lifespan.
酵母 GFP-Adf1:ura+ strain The F-BAR Cdc15 promotes contractile ring formation through the direct recruitment of the formin Cdc12.
ヒト・動物細胞 GCIY(RCB0555) , MKN-7(RCB3687) Candidate Oncogenes, ARHGAP4, NOS3, and OR51B5, for the Development of Scirrhous-type Gastric Cancer.
酵母 Stress-dependent inhibition of polarized cell growth through unbalancing the GEF/GAP regulation of Cdc42.
ヒト・動物細胞 Lu99(RCB1900) , PC-9(RCB4455) Engagement of overexpressed Her2 with GEP100 induces autonomous invasive activities and provides a biomarker for metastases of lung adenocarcinoma.
ヒト・動物細胞 TALL-1(RCB2084) Crucial role of the Rap G protein signal in Notch activation and leukemogenicity of T-cell acute lymphoblastic leukemia.
遺伝子材料 mCherry-hCdt1(30/120)/ pCSII-EF (RDB15273) , AmCyan-hGem(1/110)/pCSII-EF (RDB15274) APC(CDH1) targets MgcRacGAP for destruction in the late M phase.
酵母 BYP1419 Pop2 phosphorylation at S39 contributes to the glucose repression of stress response genes, HSP12 and HSP26.
線虫 tm2058 , tm2790 , tm2640 , tm3628 , tm3630 , tm2564 , tm1865 , tm2907 The small GTPase RAB-35 defines a third pathway that is required for the recognition and degradation of apoptotic cells.
ヒト・動物細胞 U251(RCB0461) Functional analysis of the DEPDC1 oncoantigen in malignant glioma and brain tumor initiating cells.
ヒト・動物細胞 HSC-2(RCB1945) , HSC-3(RCB1975) , HSC-4(RCB1902) , Sa3(RCB0980) , Ca9-22(RCB1976) , SAS(RCB1974) , HO-1-u-1(RCB2102) SIPA1 promotes invasion and migration in human oral squamous cell carcinoma by ITGB1 and MMP7.
線虫 tm1425 Cdc42 regulates junctional actin but not cell polarization in the Caenorhabditis elegans epidermis.
線虫 tm1909 Glia initiate brain assembly through noncanonical Chimaerin-Furin axon guidance in C. elegans.
遺伝子材料 pEF-HA-mouse MICAL-L1 (RDB15385) , pEF-Myc-mouse EHD1 (RDB15386). Rab35 establishes the EHD1-association site by coordinating two distinct effectors during neurite outgrowth.
遺伝子材料 pmStr-N1-mouse Arf6 (RDB15387) , pEGFP-C1-mouse centaurin-b2-N610A/N691A (RDB15384). Rab35 regulates Arf6 activity through centaurin-β2 (ACAP2) during neurite outgrowth.
遺伝子材料 pEGFP-C1-mouse centaurin-b2 (RDB15382) , pEGFP-C1-mouse centaurin-b2-R442Q (RDB15383). Comprehensive screening for novel rab-binding proteins by GST pull-down assay using 60 different mammalian Rabs.
遺伝子材料 pEF-T7-human TBC1D12-N (RDB14979) , pEF-T7-human TBC1D12-M (RDB14980) , pEF-T7-human TBC1D12-TBC (RDB14981) , pEGFP-C1-human TBC1D12-R559K (RDB14999) , pEGFP-C1-human TBC1D28 (RDB15015) , pEGFP-C1-human TBC1D29 (RDB15016) , pGEX-4T-3-mouse Rab11A-Q70L (RDB15028) , pGEX-4T-3-mouse Rab11A-S25N (RDB15029) , pmStr-C1-mouse Rab11A (RDB15030) , pmStr-C1-mouse Rab11A-Q70L (RDB15031) , ... TBC1D12 is a novel Rab11-binding protein that modulates neurite outgrowth of PC12 cells.
遺伝子材料 pEF-T7-human TBC1D12 (RDB14978) OATL1, a novel autophagosome-resident Rab33B-GAP, regulates autophagosomal maturation.
線虫 tm3701 , tm1826 , tm1949 Loss of the RhoGAP SRGP-1 promotes the clearance of dead and injured cells in Caenorhabditis elegans.