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  • Search Condition : Filter (MeSH = GTPase-Activating Proteins / genetics)
Species Resource
C.elegans tm748 Tissue-specific functions of the Caenorhabditis elegans p120 Ras GTPase activating protein GAP-3.
Drosophila Crossveinless-c, the Drosophila homolog of tumor suppressor DLC1, regulates directional elongation of dendritic branches via down-regulating Rho1 activity.
Arabidopsis / Cultured plant cells, genes pda08839 AGD5 is a GTPase-activating protein at the trans-Golgi network.
Yeast FY15527 Fission yeast IQGAP arranges actin filaments into the cytokinetic contractile ring.
C.elegans tm2241 TBC-2 is required for embryonic yolk protein storage and larval survival during L1 diapause in Caenorhabditis elegans.
Drosophila 31811R-2 Downregulation of Centaurin gamma1A increases synaptic transmission at Drosophila larval neuromuscular junctions.
Drosophila DGRC#104910 Adult neuronal Arf6 controls ethanol-induced behavior with Arfaptin downstream of Rac1 and RhoGAP18B.
C.elegans tm2313 , tm2526 , tm1447 RAB-10-GTPase-mediated regulation of endosomal phosphatidylinositol-4,5-bisphosphate.
Drosophila 31935R-1 Regulators of autophagosome formation in Drosophila muscles.
C.elegans tm1909 Glia initiate brain assembly through noncanonical Chimaerin-Furin axon guidance in C. elegans.
C.elegans tm1425 Cdc42 regulates junctional actin but not cell polarization in the Caenorhabditis elegans epidermis.
C.elegans tm2616 , tm1909 Dynamic Opposition of Clustered Proteins Stabilizes Cortical Polarity in the C. elegans Zygote.
C.elegans tm1447 , tm1877 Inhibition of Cytohesins Protects against Genetic Models of Motor Neuron Disease.
C.elegans tm1956 , tm1877 , tm3124 , tm1447 Asymmetric neuroblast divisions producing apoptotic cells require the cytohesin GRP-1 in Caenorhabditis elegans.
DNA material pEGFP-C1-mouse centaurin-b2 (RDB15382) , pEGFP-C1-mouse centaurin-b2-R442Q (RDB15383). Comprehensive screening for novel rab-binding proteins by GST pull-down assay using 60 different mammalian Rabs.
DNA material pmStr-N1-mouse Arf6 (RDB15387) , pEGFP-C1-mouse centaurin-b2-N610A/N691A (RDB15384). Rab35 regulates Arf6 activity through centaurin-β2 (ACAP2) during neurite outgrowth.
DNA material pEF-HA-mouse MICAL-L1 (RDB15385) , pEF-Myc-mouse EHD1 (RDB15386). Rab35 establishes the EHD1-association site by coordinating two distinct effectors during neurite outgrowth.
DNA material pEF-T7-human TBC1D12 (RDB14978) OATL1, a novel autophagosome-resident Rab33B-GAP, regulates autophagosomal maturation.
DNA material pEF-T7-human TBC1D12-N (RDB14979) , pEF-T7-human TBC1D12-M (RDB14980) , pEF-T7-human TBC1D12-TBC (RDB14981) , pEGFP-C1-human TBC1D12-R559K (RDB14999) , pEGFP-C1-human TBC1D28 (RDB15015) , pEGFP-C1-human TBC1D29 (RDB15016) , pGEX-4T-3-mouse Rab11A-Q70L (RDB15028) , pGEX-4T-3-mouse Rab11A-S25N (RDB15029) , pmStr-C1-mouse Rab11A (RDB15030) , pmStr-C1-mouse Rab11A-Q70L (RDB15031) , ... TBC1D12 is a novel Rab11-binding protein that modulates neurite outgrowth of PC12 cells.
C.elegans tm3802 , tm2282 , tm3255 TBC-8, a putative RAB-2 GAP, regulates dense core vesicle maturation in Caenorhabditis elegans.