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  • 42 Hits
  • Search Condition : Filter (MeSH = GTPase-Activating Proteins / genetics)
Species Resource Title
Human and Animal Cells GCIY(RCB0555) , MKN-7(RCB3687) Candidate Oncogenes, ARHGAP4, NOS3, and OR51B5, for the Development of Scirrhous-type Gastric Cancer.
Yeast Stress-dependent inhibition of polarized cell growth through unbalancing the GEF/GAP regulation of Cdc42.
Human and Animal Cells Lu99(RCB1900) , PC-9(RCB4455) Engagement of overexpressed Her2 with GEP100 induces autonomous invasive activities and provides a biomarker for metastases of lung adenocarcinoma.
Human and Animal Cells TALL-1(RCB2084) Crucial role of the Rap G protein signal in Notch activation and leukemogenicity of T-cell acute lymphoblastic leukemia.
DNA material mCherry-hCdt1(30/120)/ pCSII-EF (RDB15273) , AmCyan-hGem(1/110)/pCSII-EF (RDB15274) APC(CDH1) targets MgcRacGAP for destruction in the late M phase.
Yeast BYP1419 Pop2 phosphorylation at S39 contributes to the glucose repression of stress response genes, HSP12 and HSP26.
C.elegans tm2058 , tm2790 , tm2640 , tm3628 , tm3630 , tm2564 , tm1865 , tm2907 The small GTPase RAB-35 defines a third pathway that is required for the recognition and degradation of apoptotic cells.
Human and Animal Cells U251(RCB0461) Functional analysis of the DEPDC1 oncoantigen in malignant glioma and brain tumor initiating cells.
Human and Animal Cells HSC-2(RCB1945) , HSC-3(RCB1975) , HSC-4(RCB1902) , Sa3(RCB0980) , Ca9-22(RCB1976) , SAS(RCB1974) , HO-1-u-1(RCB2102) SIPA1 promotes invasion and migration in human oral squamous cell carcinoma by ITGB1 and MMP7.
C.elegans tm1425 Cdc42 regulates junctional actin but not cell polarization in the Caenorhabditis elegans epidermis.
C.elegans tm1909 Glia initiate brain assembly through noncanonical Chimaerin-Furin axon guidance in C. elegans.
DNA material pEF-HA-mouse MICAL-L1 (RDB15385) , pEF-Myc-mouse EHD1 (RDB15386). Rab35 establishes the EHD1-association site by coordinating two distinct effectors during neurite outgrowth.
DNA material pmStr-N1-mouse Arf6 (RDB15387) , pEGFP-C1-mouse centaurin-b2-N610A/N691A (RDB15384). Rab35 regulates Arf6 activity through centaurin-β2 (ACAP2) during neurite outgrowth.
DNA material pEGFP-C1-mouse centaurin-b2 (RDB15382) , pEGFP-C1-mouse centaurin-b2-R442Q (RDB15383). Comprehensive screening for novel rab-binding proteins by GST pull-down assay using 60 different mammalian Rabs.
DNA material pEF-T7-human TBC1D12-N (RDB14979) , pEF-T7-human TBC1D12-M (RDB14980) , pEF-T7-human TBC1D12-TBC (RDB14981) , pEGFP-C1-human TBC1D12-R559K (RDB14999) , pEGFP-C1-human TBC1D28 (RDB15015) , pEGFP-C1-human TBC1D29 (RDB15016) , pGEX-4T-3-mouse Rab11A-Q70L (RDB15028) , pGEX-4T-3-mouse Rab11A-S25N (RDB15029) , pmStr-C1-mouse Rab11A (RDB15030) , pmStr-C1-mouse Rab11A-Q70L (RDB15031) , ... TBC1D12 is a novel Rab11-binding protein that modulates neurite outgrowth of PC12 cells.
DNA material pEF-T7-human TBC1D12 (RDB14978) OATL1, a novel autophagosome-resident Rab33B-GAP, regulates autophagosomal maturation.
C.elegans tm3701 , tm1826 , tm1949 Loss of the RhoGAP SRGP-1 promotes the clearance of dead and injured cells in Caenorhabditis elegans.
C.elegans tm2328 , tm1447 The Arf GAP CNT-2 regulates the apoptotic fate in C. elegans asymmetric neuroblast divisions.
C.elegans tm3802 , tm2282 , tm3255 TBC-8, a putative RAB-2 GAP, regulates dense core vesicle maturation in Caenorhabditis elegans.
C.elegans tm1956 , tm1877 , tm3124 , tm1447 Asymmetric neuroblast divisions producing apoptotic cells require the cytohesin GRP-1 in Caenorhabditis elegans.