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  • Search Condition : Filter (MeSH = Genetic Predisposition to Disease)
Species Resource
Rats review National BioResource Project-Rat and related activities.
Rats DA/Slc(strainID=380) , WKY/NCrlCrlj(strainID=477) Genetic mapping found major QTLs for antibody-induced glomerulonephritis in WKY rats.
Mice Mutation of Dock5, a member of the guanine exchange factor Dock180 superfamily, in the rupture of lens cataract mouse.
Drosophila Variants of the elongator protein 3 (ELP3) gene are associated with motor neuron degeneration.
Rats KDP/Tky(strainID=15) , TM/Kyo(strainID=10) Cblb is a major susceptibility gene for rat type 1 diabetes mellitus.
Rats DRH/Seac(strainID=111) , DRH.F344-Drh1/Shigm(strainID=492) Modulation of genetic resistance to hepatocarcinogenesis in DRH rats by partial hepatectomy.
Drosophila The Drosophila immune response against Gram-negative bacteria is mediated by a peptidoglycan recognition protein.
Drosophila Sep4[NP7170] (DGRC#114116) Synergistic interactions between Drosophila orthologues of genes spanned by de novo human CNVs support multiple-hit models of autism.
DNA material human RBd38E01 (HKR375297) A naturally occurring null variant of the NMDA type glutamate receptor NR3B subunit is a risk factor of schizophrenia.
Drosophila Discovering human diabetes-risk gene function with genetics and physiological assays.
Drosophila Identification of seven genes essential for male fertility through a genome-wide association study of non-obstructive azoospermia and RNA interference-mediated large-scale functional screening in Drosophila.
C.elegans tm1086 Exploring the link between MORF4L1 and risk of breast cancer.
DNA material pGL4.17 Tyk2 WT (RDB13913) , pGL4.17 Tyk2 mutant (RDB13914). Reduced Tyk2 gene expression in β-cells due to natural mutation determines susceptibility to virus-induced diabetes.
Drosophila DGRC#113334 MiR-980 Is a Memory Suppressor MicroRNA that Regulates the Autism-Susceptibility Gene A2bp1.
Mice B6.Cg-Tg(CAG-Cre)CZ-MO2Osb(RBRC01828) Propagation of trimethylated H3K27 regulated by polycomb protein EED is required for embryogenesis, hematopoietic maintenance, and tumor suppression.
C.elegans tm794 Regulation of ATG4B stability by RNF5 limits basal levels of autophagy and influences susceptibility to bacterial infection.
Rats Ascorbic acid deficiency stimulates hepatic expression of inflammatory chemokine, cytokine-induced neutrophil chemoattractant-1, in scurvy-prone ODS rats.
Rats DON/Kyo(strainID=1) , DRH/Seac(strainID=111) Low selection of preneoplastic hepatocytes after treatment with the 2-acetylaminofluorene diet-partial hepatectomy regimen in the liver of hepatocarcinogenesis-resistant DRH strain rats.
INFORMATION , Drosophila http://www.dgrc.kit.ac.jp/en/index.html Drosophila, genetic screens, and cardiac function.
DNA material p3xFLAG-CMV-10-Pemt (RDB14190) , pcDNA3-myc-CHC(232-340) (RDB14191) , pcDNA3-myc-CHC(1074-1406) (RDB14192) , pcDNA3-myc-CHC(1267-1513) (RDB14193) , pcDNA3-myc-CHC(1-1676) (RDB14194) , pcDNA3.1-p53-HA (RDB14195) , pcDNA3.1-FLAG-Pemt-HA (RDB14196). Insufficiency of phosphatidylethanolamine N-methyltransferase is risk for lean non-alcoholic steatohepatitis.