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  • 検索条件 : 絞込み (MeSH = Guanine Nucleotide Exchange Factors / genetics)
生物種 リソース名 タイトル
線虫 tm4024 , tm469 Dendrite regeneration in C. elegans is controlled by the RAC GTPase CED-10 and the RhoGEF TIAM-1.
遺伝子材料 , ヒト・動物細胞 pmStr-C1-Vps9d1 (RDB19825) , pmStr-C1-Vps9d1-Y628A (YA) (RDB19826) , COS-7(RCB0539) Vps9d1 regulates tubular endosome formation through specific activation of Rab22A.
シロイヌナズナ / 植物培養細胞・遺伝子 pst05666 , pst18264 A whole-cell electron tomography model of vacuole biogenesis in Arabidopsis root cells.
遺伝子材料 C-Epac2-Y (RDB19602) The cAMP sensor Epac2 is a direct target of antidiabetic sulfonylurea drugs.
実験動物マウス RBRC04421 The lysosomal V-ATPase a3 subunit is involved in localization of Mon1-Ccz1, the GEF for Rab7, to secretory lysosomes in osteoclasts.
ヒト・動物細胞 Lu99(RCB1900) , PC-9(RCB4455) Engagement of overexpressed Her2 with GEP100 induces autonomous invasive activities and provides a biomarker for metastases of lung adenocarcinoma.
ミヤコグサ・ダイズ pUB-GWS-GFP , pUB-GFP SPIKE1 Activates the GTPase ROP6 to Guide the Polarized Growth of Infection Threads in Lotus japonicus.
シロイヌナズナ / 植物培養細胞・遺伝子 pda Interactions between Transport Protein Particle (TRAPP) complexes and Rab GTPases in Arabidopsis.
ヒト・動物細胞 NRK49F(RCB0112) The signal pathway for the repressive effect of dipyridamole on myofibroblast transdifferentiation.
ショウジョウバエ DGRC#206863 Sec71 functions as a GEF for the small GTPase Arf1 to govern dendrite pruning of Drosophila sensory neurons.
ショウジョウバエ Rap1, Canoe and Mbt cooperate with Bazooka to promote zonula adherens assembly in the fly photoreceptor.
線虫 tm1095 , tm2807 RPM-1 and DLK-1 regulate pioneer axon outgrowth by controlling Wnt signaling.
ヒト・動物細胞 COS-7(RCB0539) Solo, a RhoA-targeting guanine nucleotide exchange factor, is critical for hemidesmosome formation and acinar development in epithelial cells.
線虫 tm4024 , tm9033 , tm2143 , tm2409 , tm2241 , tm3310 DLK-1/p38 MAP Kinase Signaling Controls Cilium Length by Regulating RAB-5 Mediated Endocytosis in Caenorhabditis elegans.
ヒト・動物細胞 VMRC-RCW(RCB1963) Guanine nucleotide exchange factor RABGEF1 regulates keratinocyte-intrinsic signaling to maintain skin homeostasis.
線虫 tm1516 The HECT Family Ubiquitin Ligase EEL-1 Regulates Neuronal Function and Development.
遺伝子材料 pEGFP-C1-human DENN (RDB15288) , pEGFP-C1-mouse DENND1A (RDB15289) , pEGFP-C1-mouse DENND3 (RDB15290). MADD/DENN/Rab3GEP functions as a guanine nucleotide exchange factor for Rab27 during granule exocytosis of rat parotid acinar cells.
実験動物マウス RBRC01081 Endocytosis following dopamine D2 receptor activation is critical for neuronal activity and dendritic spine formation via Rabex-5/PDGFRβ signaling in striatopallidal medium spiny neurons.
イネ Induced mutation lines Guanine nucleotide exchange factor 2 for Rab5 proteins coordinated with GLUP6/GEF regulates the intracellular transport of the proglutelin from the Golgi apparatus to the protein storage vacuole in rice endosperm.
線虫 tm3203 , tm2916 , tm2926 , tm3214 Neuronally expressed Ras-family GTPase Di-Ras modulates synaptic activity in Caenorhabditis elegans.