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  • 32 Hits
  • Search Condition : Filter (MeSH = Guanine Nucleotide Exchange Factors / genetics)
Species Resource
Xenopus tropicalis XRASGRP2 is essential for blood vessel formation during Xenopus development.
DNA material CSII-CMV-MCS (RDB04377) , pCAG-HIVgp (RDB04394) , pCMV-VSV-G-RSV-Rev (RDB04393) Impaired vascular development in the yolk sac and allantois in mice lacking RA-GEF-1.
Drosophila Specific retention of the protostome-specific PsGEF may parallel with the evolution of mushroom bodies in insect and lophotrochozoan brains.
Pathogenic microorganisms ? Enteropathogenic Escherichia coli activates the RhoA signaling pathway via the stimulation of GEF-H1.
Drosophila 12085R-2 , 12085R-4 Hfp inhibits Drosophila myc transcription and cell growth in a TFIIH/Hay-dependent manner.
Yeast FY12587 Roles of putative Rho-GEF Gef2 in division-site positioning and contractile-ring function in fission yeast cytokinesis.
Drosophila DGRC#109893 , DGRC#109899 , DGRC#109910 , DGRC#109912 , DGRC#109917 Trio combines with dock to regulate Pak activity during photoreceptor axon pathfinding in Drosophila.
Drosophila DGRC#109572 , DGRC#109575 Synaptic development is controlled in the periactive zones of Drosophila synapses.
Drosophila DGRC#206863 Sec71 functions as a GEF for the small GTPase Arf1 to govern dendrite pruning of Drosophila sensory neurons.
C.elegans tm1516 The HECT Family Ubiquitin Ligase EEL-1 Regulates Neuronal Function and Development.
C.elegans tm3767 , tm1693 , tm1877 , tm1447 An AGEF-1/Arf GTPase/AP-1 ensemble antagonizes LET-23 EGFR basolateral localization and signaling during C. elegans vulva induction.
C.elegans tm1956 The insulin/IGF signaling regulators cytohesin/GRP-1 and PIP5K/PPK-1 modulate susceptibility to excitotoxicity in C. elegans.
C.elegans tm1956 , tm1877 , tm3124 , tm1447 Asymmetric neuroblast divisions producing apoptotic cells require the cytohesin GRP-1 in Caenorhabditis elegans.
C.elegans tm3663 Mechanisms of CDC-42 activation during contact-induced cell polarization.
C.elegans tm2784 RAE-1, a novel PHR binding protein, is required for axon termination and synapse formation in Caenorhabditis elegans.
Drosophila 10701-R1 , 10701-R3 , 12489-R1 , 12489-R2 , 1283-R1 , 1283-R2 , 15288-R2 , 1536-R4 , 1822-R1 , 1822-R3 , ... Notch directly regulates the cell morphogenesis genes Reck, talin and trio in adult muscle progenitors.
DNA material pEGFP-C1-human DENN (RDB15288) , pEGFP-C1-mouse DENND1A (RDB15289) , pEGFP-C1-mouse DENND3 (RDB15290). MADD/DENN/Rab3GEP functions as a guanine nucleotide exchange factor for Rab27 during granule exocytosis of rat parotid acinar cells.
C.elegans tm1556 , tm597 The Rac GTP exchange factor TIAM-1 acts with CDC-42 and the guidance receptor UNC-40/DCC in neuronal protrusion and axon guidance.
C.elegans tm1512 , tm1555 Rabx-5 regulates RAB-5 early endosomal compartments and synaptic vesicles in C. elegans.
C.elegans tm3203 , tm2916 , tm2926 , tm3214 Neuronally expressed Ras-family GTPase Di-Ras modulates synaptic activity in Caenorhabditis elegans.