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  • Search Condition : Filter (MeSH = Histone-Lysine N-Methyltransferase / genetics)
Species Resource Title
Human and Animal Cells KLM-1(RCB2138) , MIA Paca2(RCB2094) Identification of a novel target of SETD1A histone methyltransferase and the clinical significance in pancreatic cancer.
Yeast FY11202 , FY21235 , FY21234 , FY20045 , FY20043 , FY20039 Set2 regulates Ccp1 and Swc2 to ensure centromeric stability by retargeting CENP-A.
DNA material pCAG-HIVgp (RDB04394) , pCMV-VSV-G-RSV-Rev (RDB04393) SETDB1 Inhibits p53-Mediated Apoptosis and Is Required for Formation of Pancreatic Ductal Adenocarcinomas in Mice.
C.elegans tm6845 , tm6748 , tm2649 , tm1116 SETDB1-like MET-2 promotes transcriptional silencing and development independently of its H3K9me-associated catalytic activity.
DNA material px330-mC/Ctag2_Up (RDB19250) , px330-mC/Ctag2_Down (RDB19251) , px330-mC/4930447F04Rik_Up (RDB19252) , px330-mC/4930447F04Rik_Down (RDB19253) , px330-mC/Mir465_cluster_Up (RDB19254) , px330-mC/Mir465_cluster_Down (RDB19255) , px330-mC/Gm1140_Up (RDB19256) , px330-mC/Gm1140-Gm14692_Mid (RDB19257) , px330-mC/Gm14692_Down (RDB19258) , px330-mC/4933436l01Rik_Up (RDB19259) , ... Reverse genetics reveals single gene of every candidate on Hybrid sterility, X Chromosome QTL 2 (Hstx2) are dispensable for spermatogenesis.
Human and Animal Cells KP4(RCB1005) SETD5-Coordinated Chromatin Reprogramming Regulates Adaptive Resistance to Targeted Pancreatic Cancer Therapy.
Human and Animal Cells KP4(RCB1005) , PK-1(RCB1972) Bromodomain Protein BRD4 Is a Transcriptional Repressor of Autophagy and Lysosomal Function.
C.elegans tm2649 , tm1116 Argonaute NRDE-3 and MBT domain protein LIN-61 redundantly recruit an H3K9me3 HMT to prevent embryonic lethality and transposon expression.
C.elegans tm1400 , tm1620 , tm1200 Gametes deficient for Pot1 telomere binding proteins alter levels of telomeric foci for multiple generations.
C.elegans tm12491 , tm1200 Intertissue small RNA communication mediates the acquisition and inheritance of hormesis in Caenorhabditis elegans.
Yeast FYP4222 , FYP4223 , FYP4224 , FYP4225 , FYP4226 , FYP4227 , FYP4228 , FYP4229 , FYP4230 , FYP4231 Heterochromatin suppresses gross chromosomal rearrangements at centromeres by repressing Tfs1/TFIIS-dependent transcription.
Human and Animal Cells EBC-1(RCB1965) , LK-2(RCB1970) Elevated NSD3 histone methylation activity drives squamous cell lung cancer.
Drosophila 3307R-3 Histone lysine methyltransferase Pr-set7/SETD8 promotes neural stem cell reactivation.
Human and Animal Cells OVK18(RCB1903) , JHOC-5(RCB1520) , JHOC-7(RCB1688) , JHOC-8(RCB1723) , JHOC-9(RCB2226) , JHOS-2(RCB1521) , JHOS-4(RCB1678) Selective Killing of SMARCA2- and SMARCA4-deficient Small Cell Carcinoma of the Ovary, Hypercalcemic Type Cells by Inhibition of EZH2: In Vitro and In Vivo Preclinical Models.
C.elegans Two conserved epigenetic regulators prevent healthy ageing.
C.elegans tm1145 Synergistic lethality between BRCA1 and H3K9me2 loss reflects satellite derepression.
C.elegans tm1227 , tm294 Active chromatin marks drive spatial sequestration of heterochromatin in C. elegans nuclei.
C.elegans tm6748 Heterochromatic foci and transcriptional repression by an unstructured MET-2/SETDB1 co-factor LIN-65.
Drosophila Effect of heterochromatin stability on intestinal stem cell aging in Drosophila.
Drosophila Epigenetic regulation of starvation-induced autophagy in Drosophila by histone methyltransferase G9a.