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  • 検索条件 : 絞込み (MeSH = Kelch-Like ECH-Associated Protein 1 / genetics)
生物種 リソース名 タイトル
ショウジョウバエ DGRC#113094 Protective effect of agar oligosaccharide on male Drosophila melanogaster suffering from oxidative stress via intestinal microflora activating the Keap1-Nrf2 signaling pathway.
ヒト・動物細胞 LK-2(RCB1970) Targeting NFE2L2/KEAP1 Mutations in Advanced NSCLC With the TORC1/2 Inhibitor TAK-228.
ゼブラフィッシュ nfe2l2a it321 Soy-Derived Equol Induces Antioxidant Activity in Zebrafish in an Nrf2-Independent Manner.
ゼブラフィッシュ keap1a it302 , keap1b it308 Genetic hyperactivation of Nrf2 causes larval lethality in Keap1a and Keap1b-double-knockout zebrafish.
ゼブラフィッシュ Tg(-3.5gstp1:GFP)it416b Z-REX uncovers a bifurcation in function of Keap1 paralogs.
ショウジョウバエ DGRC#104055 Single-cell transcriptomics identifies Keap1-Nrf2 regulated collective invasion in a Drosophila tumor model.
ヒト・動物細胞 Hep G2(RCB1886) Activation of the Keap1/Nrf2 Pathway as an Adaptive Response to an Electrophilic Metabolite of Morphine.
ヒト・動物細胞 A549(RCB0098) Yeast β-glucan Increases Etoposide Sensitivity in Lung Cancer Cell Line A549 by Suppressing Nuclear Factor Erythroid 2-Related Factor 2 via the Noncanonical Nuclear Factor Kappa B Pathway.
ヒト・動物細胞 Atg5^(-/-)MEF(RCB2711) , Atg7 -/- MEFs(RCB3707) Basal Autophagy Is Necessary for A Pharmacologic PPARα Transactivation.
ヒト・動物細胞 LC-1F(RCB0439) , EBC-1(RCB1965) , LK-2(RCB1970) , RERF-LC-KJ(RCB1313) , RERF-LC-AI(RCB0444) , Lu99(RCB1900) , Sq-1(RCB1905) , LU65(RCB1967) , IA-LM(RCB0554) Impacts of NRF2 activation in non-small-cell lung cancer cell lines on extracellular metabolites.
ヒト・動物細胞 Hep G2(RCB1886) A strategy for repression of arsenic toxicity through nuclear factor E2 related factor 2 activation mediated by the (E)-2-alkenals in Coriandrum sativum L. leaf extract.
ヒト・動物細胞 TGBC24TKB(RCB1196) , TGBC2TKB(RCB1130) , G-415(RCB2640) Integrated genomic analysis reveals mutated ELF3 as a potential gallbladder cancer vaccine candidate.
ショウジョウバエ 3962R-1 , 3962R-2 N-acetyl-l-tyrosine is an intrinsic triggering factor of mitohormesis in stressed animals.
実験動物マウス RBRC01388 Moderate Nrf2 Activation by Genetic Disruption of Keap1 Has Sex-Specific Effects on Bone Mass in Mice.
ヒト・動物細胞 293(RCB1637) Structural instability of IκB kinase β promotes autophagic degradation through enhancement of Keap1 binding.
ヒト・動物細胞 LK-2(RCB1970) , TGBC24TKB(RCB1196) The discovery and characterization of K-563, a novel inhibitor of the Keap1/Nrf2 pathway produced by Streptomyces sp.
線虫 tm1817 , tm2391 The Skp1 Homologs SKR-1/2 Are Required for the Caenorhabditis elegans SKN-1 Antioxidant/Detoxification Response Independently of p38 MAPK.
実験動物マウス RBRC01388 , RBRC01390 Effects of deficiency of Kelch-like ECH-associated protein 1 on skeletal organization: a mechanism for diminished nuclear factor of activated T cells cytoplasmic 1 during osteoclastogenesis.