生物種
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リソース名
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RRC ID
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タイトル
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ジャーナル
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公開日
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外部リンク
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ショウジョウバエ
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DGRC#113094
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79042
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Protective effect of agar oligosaccharide on male Drosophila melanogaster suffering from oxidative stress via intestinal microflora activating the Keap1-Nrf2 signaling pathway.
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Carbohydr Polym |
2023-8-1 |
Pubmed
Full text
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ヒト・動物細胞
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LK-2(RCB1970)
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78706
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Targeting NFE2L2/KEAP1 Mutations in Advanced NSCLC With the TORC1/2 Inhibitor TAK-228.
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J Thorac Oncol |
2023-4-1 |
Pubmed
Full text
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ゼブラフィッシュ
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nfe2l2a it321
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75008
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Soy-Derived Equol Induces Antioxidant Activity in Zebrafish in an Nrf2-Independent Manner.
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Int J Mol Sci |
2022-5-8 |
Pubmed
Full text
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ゼブラフィッシュ
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keap1a it302
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keap1b it308
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75007
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Genetic hyperactivation of Nrf2 causes larval lethality in Keap1a and Keap1b-double-knockout zebrafish.
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Redox Biol |
2023-6-1 |
Pubmed
Full text
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ゼブラフィッシュ
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Tg(-3.5gstp1:GFP)it416b
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74791
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Z-REX uncovers a bifurcation in function of Keap1 paralogs.
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Elife |
2022-10-27 |
Pubmed
Full text
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ショウジョウバエ
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DGRC#104055
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74724
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Single-cell transcriptomics identifies Keap1-Nrf2 regulated collective invasion in a Drosophila tumor model.
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Elife |
2022-11-2 |
Pubmed
Full text
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ヒト・動物細胞
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Hep G2(RCB1886)
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73742
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Activation of the Keap1/Nrf2 Pathway as an Adaptive Response to an Electrophilic Metabolite of Morphine.
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Biol Pharm Bull |
2023-1-1 |
Pubmed
Full text
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ヒト・動物細胞
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A549(RCB0098)
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71614
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Yeast β-glucan Increases Etoposide Sensitivity in Lung Cancer Cell Line A549 by Suppressing Nuclear Factor Erythroid 2-Related Factor 2 via the Noncanonical Nuclear Factor Kappa B Pathway.
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Mol Pharmacol |
2022-4-1 |
Pubmed
Full text
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ヒト・動物細胞
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Atg5^(-/-)MEF(RCB2711)
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Atg7 -/- MEFs(RCB3707)
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70023
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Basal Autophagy Is Necessary for A Pharmacologic PPARα Transactivation.
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Cells |
2022-2-21 |
Pubmed
Full text
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ヒト・動物細胞
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LC-1F(RCB0439)
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EBC-1(RCB1965)
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LK-2(RCB1970)
,
RERF-LC-KJ(RCB1313)
,
RERF-LC-AI(RCB0444)
,
Lu99(RCB1900)
,
Sq-1(RCB1905)
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LU65(RCB1967)
,
IA-LM(RCB0554)
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63547
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Impacts of NRF2 activation in non-small-cell lung cancer cell lines on extracellular metabolites.
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Cancer Sci |
2020-2-1 |
Pubmed
Full text
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ヒト・動物細胞
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Hep G2(RCB1886)
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63020
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A strategy for repression of arsenic toxicity through nuclear factor E2 related factor 2 activation mediated by the (E)-2-alkenals in Coriandrum sativum L. leaf extract.
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Food Chem Toxicol |
2020-11-1 |
Pubmed
Full text
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ヒト・動物細胞
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TGBC24TKB(RCB1196)
,
TGBC2TKB(RCB1130)
,
G-415(RCB2640)
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63016
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Integrated genomic analysis reveals mutated ELF3 as a potential gallbladder cancer vaccine candidate.
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Nat Commun |
2020-8-24 |
Pubmed
Full text
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ショウジョウバエ
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3962R-1
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3962R-2
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58481
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N-acetyl-l-tyrosine is an intrinsic triggering factor of mitohormesis in stressed animals.
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EMBO Rep |
2020-5-6 |
Pubmed
Full text
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実験動物マウス
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RBRC01388
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58388
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Moderate Nrf2 Activation by Genetic Disruption of Keap1 Has Sex-Specific Effects on Bone Mass in Mice.
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Sci Rep |
2020-1-15 |
Pubmed
Full text
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ヒト・動物細胞
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293(RCB1637)
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55887
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Structural instability of IκB kinase β promotes autophagic degradation through enhancement of Keap1 binding.
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PLoS One |
2018-11-30 |
Pubmed
Full text
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ヒト・動物細胞
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LK-2(RCB1970)
,
TGBC24TKB(RCB1196)
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54861
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The discovery and characterization of K-563, a novel inhibitor of the Keap1/Nrf2 pathway produced by Streptomyces sp.
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Cancer Med |
2019-3-1 |
Pubmed
Full text
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線虫
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tm1817
,
tm2391
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53350
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The Skp1 Homologs SKR-1/2 Are Required for the Caenorhabditis elegans SKN-1 Antioxidant/Detoxification Response Independently of p38 MAPK.
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PLoS Genet |
2016-10-1 |
Pubmed
Full text
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実験動物マウス
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RBRC01388
,
RBRC01390
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48723
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Effects of deficiency of Kelch-like ECH-associated protein 1 on skeletal organization: a mechanism for diminished nuclear factor of activated T cells cytoplasmic 1 during osteoclastogenesis.
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FASEB J |
2017-9-1 |
Pubmed
Full text
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