• 7 Hits
  • Search Condition : Filter (MeSH = Leukemia, Lymphocytic, Chronic, B-Cell / metabolism)
Species Resource Title
Human and Animal Cells StromaNKtert(RCB2350) The multi-kinase inhibitor TG02 induces apoptosis and blocks B-cell receptor signaling in chronic lymphocytic leukemia through dual mechanisms of action.
Human and Animal Cells DT40(RCB1464) Hypermorphic mutation of phospholipase C, γ2 acquired in ibrutinib-resistant CLL confers BTK independency upon B-cell receptor activation.
Human and Animal Cells StromaNKtert(RCB2350) Impact of bone marrow stromal cells on Bcl-2 family members in chronic lymphocytic leukemia.
Human and Animal Cells StromaNKtert(RCB2350) Decreased mitochondrial apoptotic priming underlies stroma-mediated treatment resistance in chronic lymphocytic leukemia.
Human and Animal Cells StromaNKtert(RCB2350) , KUSA-H1(RCB1990) Homoharringtonine reduced Mcl-1 expression and induced apoptosis in chronic lymphocytic leukemia.
Human and Animal Cells K562 , Jurkat(RCB0806) CMC-544 (inotuzumab ozogamicin) shows less effect on multidrug resistant cells: analyses in cell lines and cells from patients with B-cell chronic lymphocytic leukaemia and lymphoma.
Human and Animal Cells KUSA-H1(RCB1990) , 9-15C(RCB2323) , TSt-4(RCB2116) The phosphoinositide 3'-kinase delta inhibitor, CAL-101, inhibits B-cell receptor signaling and chemokine networks in chronic lymphocytic leukemia.