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  • Search Condition : Filter (MeSH = Leukemia, Myeloid, Acute / genetics)
Species Resource Title
Human and Animal Cells KG-1(RCB1166) DNMT3A R882 mutants interact with polycomb proteins to block haematopoietic stem and leukaemic cell differentiation.
Human and Animal Cells StromaNKtert(RCB2350) The oncometabolite R-2-hydroxyglutarate activates NF-κB-dependent tumor-promoting stromal niche for acute myeloid leukemia cells.
Drosophila A genetic screen in Drosophila uncovers the multifaceted properties of the NUP98-HOXA9 oncogene.
Human and Animal Cells 32Dcl3(RCB1377) Co-expression of wild-type FLT3 attenuates the inhibitory effect of FLT3 inhibitor on FLT3 mutated leukemia cells.
DNA material , Human and Animal Cells pENTR4-H1tetOx1 (RDB07916) , CS-RfA-ETV (RDB08020) , CSIV-TRE-RfA-UbC-KT (RDB12878) , THP-1(RCB1189) , KG-1a(RCB1928) Pivotal role of DPYSL2A in KLF4-mediated monocytic differentiation of acute myeloid leukemia cells.
Human and Animal Cells RPMI8226(RCB3010) , KG-1(RCB1166) , MOLT-4(RCB0206) Targeting Notch-1 positive acute leukemia cells by novel fucose-bound liposomes carrying daunorubicin.
Human and Animal Cells EoL-1 cell(RCB0641) Isolation of human mAbs that directly modulate FMS-related tyrosine kinase 3 signaling.
Mice RBRC01361 Opposing effects of acute versus chronic inhibition of p53 on decitabine's efficacy in myeloid neoplasms.
Human and Animal Cells HL60 , U937 Cell-based evaluation of changes in coagulation activity induced by antineoplastic drugs for the treatment of acute myeloid leukemia.
DNA material pENTR4-H1tetOx1 (RDB07916) , CS-RfA-ETBsd (RDB07917) , CS-RfA-ETV (RDB08020) , CS-RfA-ETR (RDB08362). RUNX transcription factors potentially control E-selectin expression in the bone marrow vascular niche in mice.
DNA material pENTR4-H1tetOx1 (RDB07916) , CS-RfA-ETBsd (RDB07917) , CS-RfA-ETV (RDB08020) , CS-RfA-ETR (RDB08362) , CSII-EF-MCS-IRES2-Venus (RDB04384) , CSII-EF-MCS-IRES2-hKO1 (RDB07915). Autonomous feedback loop of RUNX1-p53-CBFB in acute myeloid leukemia cells.
Mice RBRC01834 Acquired expression of CblQ367P in mice induces dysplastic myelopoiesis mimicking chronic myelomonocytic leukemia.
Human and Animal Cells HL60(RCB0041) Phosphodiesterase 5 inhibitor acts as a potent agent sensitizing acute myeloid leukemia cells to 67-kDa laminin receptor-dependent apoptosis.
Human and Animal Cells EoL-1 cell(RCB0641) CD34⁺/CD38⁻ acute myelogenous leukemia cells aberrantly express CD82 which regulates adhesion and survival of leukemia stem cells.
Human and Animal Cells MC3T3-E1(RCB1126) , HNT-34(RCB1296) The increased expression of integrin α6 (ITGA6) enhances drug resistance in EVI1(high) leukemia.
Human and Animal Cells THP-1(RCB1189) C/EBPalpha and C/EBPvarepsilon induce the monocytic differentiation of myelomonocytic cells with the MLL-chimeric fusion gene.
DNA material pRx nZ ires Neo (RDB01699). Proliferation and survival signaling from both Jak2-V617F and Lyn involving GSK3 and mTOR/p70S6K/4EBP1 in PVTL-1 cell line newly established from acute myeloid leukemia transformed from polycythemia vera.
Drosophila 1765R-2 , 1765R-4 , 7404R-2 , 7404R-3 , 9310R-1 , 9310R-2 , 11783R-1 , 11783R-2 Genetic manipulation of AML1-ETO-induced expansion of hematopoietic precursors in a Drosophila model.
DNA material pCAmKL (RDB1528) , pCAmIL3 (RDB1506) Conditional MN1-TEL knock-in mice develop acute myeloid leukemia in conjunction with overexpression of HOXA9.
Human and Animal Cells M1(RCB0169) DAP12 ITAM motif regulates differentiation and apoptosis in M1 leukemia cells.