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  • 検索条件 : 絞込み (MeSH = Mechanistic Target of Rapamycin Complex 1 / metabolism*)
生物種 リソース名 タイトル
線虫 tm4397 , tm4212 ATF-4 and hydrogen sulfide signalling mediate longevity in response to inhibition of translation or mTORC1.
線虫 tm6026 Increased mitochondrial calcium uptake and concomitant mitochondrial activity by presenilin loss promotes mTORC1 signaling to drive neurodegeneration.
ショウジョウバエ DGRC#104863 A TORC1-histone axis regulates chromatin organisation and non-canonical induction of autophagy to ameliorate ageing.
ゼブラフィッシュ Tg(vglut2a:loxP-DsRed-loxP-GFP) G3BPs tether the TSC complex to lysosomes and suppress mTORC1 signaling.
ヒト・動物細胞 293(RCB1637) Evaluation of the Binding Kinetics of RHEB with mTORC1 by In-Cell and In Vitro Assays.
ヒト・動物細胞 C2C12(RCB0987) The involvement of Sestrin2 in the effect of IGF-I and leucine on mTROC1 activity in C2C12 and L6 myocytes.
ショウジョウバエ 5671R-2 Differential metabolic sensitivity of insulin-like-response- and TORC1-dependent overgrowth in Drosophila fat cells.
ヒト・動物細胞 NOS-1(RCB1032) Metabolic compensation activates pro-survival mTORC1 signaling upon 3-phosphoglycerate dehydrogenase inhibition in osteosarcoma.
ショウジョウバエ 10539R-2 Drosophila Activin signaling promotes muscle growth through InR/TORC1-dependent and -independent processes.
ショウジョウバエ 5520R-1 , 18255R-1 , 31014R-2 , 9726R-1 , 31015R-1 Mislocalization of TORC1 to Lysosomes Caused by KIF11 Inhibition Leads to Aberrant TORC1 Activity.
線虫 tm1133 , tm1108 Neuronal TORC1 modulates longevity via AMPK and cell nonautonomous regulation of mitochondrial dynamics in C. elegans.
線虫 tm4931 , tm4642 The Rheb-TORC1 signaling axis functions as a developmental checkpoint.
酵母 FY9908 , FY9910 , FY21019 Maf1-dependent transcriptional regulation of tRNAs prevents genomic instability and is associated with extended lifespan.
遺伝子材料 pCAG-HIVgp (RDB04394) , pCMV-VSV-G-RSV-Rev (RDB04393) Noncanonical Pathway for Regulation of CCL2 Expression by an mTORC1-FOXK1 Axis Promotes Recruitment of Tumor-Associated Macrophages.
線虫 tm6608 mTOR Regulates Phase Separation of PGL Granules to Modulate Their Autophagic Degradation.