生物種
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リソース名
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RRC ID
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タイトル
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ジャーナル
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公開日
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外部リンク
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線虫
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tm4397
,
tm4212
|
76065
|
ATF-4 and hydrogen sulfide signalling mediate longevity in response to inhibition of translation or mTORC1.
|
Nat Commun |
2022-2-18 |
Pubmed
Full text
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線虫
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tm6026
|
76046
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Increased mitochondrial calcium uptake and concomitant mitochondrial activity by presenilin loss promotes mTORC1 signaling to drive neurodegeneration.
|
Aging Cell |
2021-10-1 |
Pubmed
Full text
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ショウジョウバエ
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DGRC#104863
|
70850
|
A TORC1-histone axis regulates chromatin organisation and non-canonical induction of autophagy to ameliorate ageing.
|
Elife |
2021-5-14 |
Pubmed
Full text
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ゼブラフィッシュ
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Tg(vglut2a:loxP-DsRed-loxP-GFP)
|
70311
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G3BPs tether the TSC complex to lysosomes and suppress mTORC1 signaling.
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Cell |
2021-2-4 |
Pubmed
Full text
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ヒト・動物細胞
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293(RCB1637)
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68863
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Evaluation of the Binding Kinetics of RHEB with mTORC1 by In-Cell and In Vitro Assays.
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Int J Mol Sci |
2021-8-16 |
Pubmed
Full text
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ヒト・動物細胞
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C2C12(RCB0987)
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67578
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The involvement of Sestrin2 in the effect of IGF-I and leucine on mTROC1 activity in C2C12 and L6 myocytes.
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Growth Horm IGF Res |
2021-8-1 |
Pubmed
Full text
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ショウジョウバエ
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5671R-2
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64352
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Differential metabolic sensitivity of insulin-like-response- and TORC1-dependent overgrowth in Drosophila fat cells.
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Genetics |
2021-3-3 |
Pubmed
Full text
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ヒト・動物細胞
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NOS-1(RCB1032)
|
63636
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Metabolic compensation activates pro-survival mTORC1 signaling upon 3-phosphoglycerate dehydrogenase inhibition in osteosarcoma.
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Cell Rep |
2021-1-26 |
Pubmed
Full text
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ショウジョウバエ
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10539R-2
|
61885
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Drosophila Activin signaling promotes muscle growth through InR/TORC1-dependent and -independent processes.
|
Development |
2021-1-10 |
Pubmed
Full text
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ショウジョウバエ
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5520R-1
,
18255R-1
,
31014R-2
,
9726R-1
,
31015R-1
|
61045
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Mislocalization of TORC1 to Lysosomes Caused by KIF11 Inhibition Leads to Aberrant TORC1 Activity.
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Mol Cells |
2020-8-31 |
Pubmed
Full text
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線虫
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tm1133
,
tm1108
|
59633
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Neuronal TORC1 modulates longevity via AMPK and cell nonautonomous regulation of mitochondrial dynamics in C. elegans.
|
Elife |
2019-8-14 |
Pubmed
Full text
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線虫
|
tm4931
,
tm4642
|
59484
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The Rheb-TORC1 signaling axis functions as a developmental checkpoint.
|
Development |
2020-3-2 |
Pubmed
Full text
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酵母
|
FY9908
,
FY9910
,
FY21019
|
58218
|
Maf1-dependent transcriptional regulation of tRNAs prevents genomic instability and is associated with extended lifespan.
|
Aging Cell |
2020-2-1 |
Pubmed
Full text
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遺伝子材料
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pCAG-HIVgp (RDB04394)
,
pCMV-VSV-G-RSV-Rev (RDB04393)
|
56703
|
Noncanonical Pathway for Regulation of CCL2 Expression by an mTORC1-FOXK1 Axis Promotes Recruitment of Tumor-Associated Macrophages.
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Cell Rep |
2017-11-28 |
Pubmed
Full text
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線虫
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tm6608
|
56245
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mTOR Regulates Phase Separation of PGL Granules to Modulate Their Autophagic Degradation.
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Cell |
2018-9-6 |
Pubmed
Full text
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