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  • Search Condition : Filter (MeSH = Mechanistic Target of Rapamycin Complex 1 / metabolism*)
Species Resource Title
C.elegans tm4397 , tm4212 ATF-4 and hydrogen sulfide signalling mediate longevity in response to inhibition of translation or mTORC1.
C.elegans tm6026 Increased mitochondrial calcium uptake and concomitant mitochondrial activity by presenilin loss promotes mTORC1 signaling to drive neurodegeneration.
Drosophila DGRC#104863 A TORC1-histone axis regulates chromatin organisation and non-canonical induction of autophagy to ameliorate ageing.
Zebrafish Tg(vglut2a:loxP-DsRed-loxP-GFP) G3BPs tether the TSC complex to lysosomes and suppress mTORC1 signaling.
Human and Animal Cells 293(RCB1637) Evaluation of the Binding Kinetics of RHEB with mTORC1 by In-Cell and In Vitro Assays.
Human and Animal Cells C2C12(RCB0987) The involvement of Sestrin2 in the effect of IGF-I and leucine on mTROC1 activity in C2C12 and L6 myocytes.
Drosophila 5671R-2 Differential metabolic sensitivity of insulin-like-response- and TORC1-dependent overgrowth in Drosophila fat cells.
Human and Animal Cells NOS-1(RCB1032) Metabolic compensation activates pro-survival mTORC1 signaling upon 3-phosphoglycerate dehydrogenase inhibition in osteosarcoma.
Drosophila 10539R-2 Drosophila Activin signaling promotes muscle growth through InR/TORC1-dependent and -independent processes.
Drosophila 5520R-1 , 18255R-1 , 31014R-2 , 9726R-1 , 31015R-1 Mislocalization of TORC1 to Lysosomes Caused by KIF11 Inhibition Leads to Aberrant TORC1 Activity.
C.elegans tm1133 , tm1108 Neuronal TORC1 modulates longevity via AMPK and cell nonautonomous regulation of mitochondrial dynamics in C. elegans.
C.elegans tm4931 , tm4642 The Rheb-TORC1 signaling axis functions as a developmental checkpoint.
Yeast FY9908 , FY9910 , FY21019 Maf1-dependent transcriptional regulation of tRNAs prevents genomic instability and is associated with extended lifespan.
DNA material pCAG-HIVgp (RDB04394) , pCMV-VSV-G-RSV-Rev (RDB04393) Noncanonical Pathway for Regulation of CCL2 Expression by an mTORC1-FOXK1 Axis Promotes Recruitment of Tumor-Associated Macrophages.
C.elegans tm6608 mTOR Regulates Phase Separation of PGL Granules to Modulate Their Autophagic Degradation.