論文 - 詳細
| RRC ID | 76046 |
|---|---|
| 著者 | Ryan KC, Ashkavand Z, Sarasija S, Laboy JT, Samarakoon R, Norman KR. |
| タイトル | Increased mitochondrial calcium uptake and concomitant mitochondrial activity by presenilin loss promotes mTORC1 signaling to drive neurodegeneration. |
| ジャーナル | Aging Cell |
| 巻・号 | 20(10) |
| ページ | e13472 |
| 公開日 | 2021-10-1 |
| DOI | 10.1111/acel.13472 |
| PMID | 34499406 |
| PMC | PMC8520713 |
| MeSH | Alzheimer Disease / genetics* Animals Caenorhabditis elegans / genetics* Caenorhabditis elegans Proteins / metabolism* Calcium / metabolism* Mechanistic Target of Rapamycin Complex 1 / metabolism* Mitochondria / metabolism* Neurodegenerative Diseases / genetics* Neurodegenerative Diseases / pathology Presenilins / metabolism* Signal Transduction |
| リソース情報 | |
| 線虫 | tm6026 |