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Species Resource Title
Human and Animal Cells RBE(RCB1292) MAPK Pathway Mutations Emerge in Mutant IDH1 Inhibitor-Resistant Cholangiocarcinoma and Attenuate the IFN Response.
Drosophila DGRC#119830 The first deltex null mutant indicates tissue-specific deltex-dependent Notch signaling in Drosophila.
Mice RBRC01238 , RBRC01249 , RBRC00653 , RBRC01247 , RBRC00738 , RBRC03108 , RBRC01167 Apobec3 shows rapid evolution in house mouse subspecies and unusual hypermutation patterns of endogenous mouse mammary tumor viruses.
Tomato TOMJPF00001 , TOMJPE2811-1 , TOMJPG0114-1 SlIAA9 mutation enhances tomato seed resilience to heat stress.
C.elegans tm6026 Presenilin mutations disrupt iron homeostasis to promote ferroptosis mediated neurodegeneration in Caenorhabditis elegans.
C.elegans tm3574 , tm5906 , tm5719 , tm2462 The transsulfuration pathway suppresses the embryonic lethal phenotype of glutathione reductase mutants in Caenorhabditis elegans.
C.elegans tm1552 High-throughput behavioural phenotyping of 25 C. elegans disease models including patient-specific mutations.
Arabidopsis / Cultured plant cells, genes pst11704 , pst05619 Early germination of Arabidopsis pollen in a double null mutant for the arabinogalactan protein genes AGP6 and AGP11.
Drosophila DGRC#102873 Drosophila Col4a1 Glycine mutations highlight allelic heterogeneity and mechanistic pleiotropy.
Zebrafish Tg(vglut2a:loxP-DsRed-loxP-GFP) , Tg(gad1b:|R|-GFP) Mutations in the microexon splicing regulator srrm4 have minor phenotypic effects on zebrafish neural development.
Zebrafish UAS:GCaMP7a Defects in Exosome Biogenesis Are Associated with Sensorimotor Defects in Zebrafish vps4a Mutants.
Human and Animal Cells 293T(RCB2202) Intra-patient neuraminidase mutations in avian H5N1 influenza virus reduce sialidase activity to complement weaker hemagglutinin binding and facilitate human infection.
Human and Animal Cells HKBML(RCB0820) A novel stroma-dependent leukemia cell line from a patient with mixed-phenotype acute leukemia with Ph chromosome and PAX5 mutation.
Human and Animal Cells Ba/F3(RCB0805) Zidesamtinib Selective Targeting of Diverse ROS1 Drug-Resistant Mutations.
Human and Animal Cells KP4(RCB1005) Targeting the SHOC2-RAS interaction in RAS-mutant cancers.
Human and Animal Cells TIG-3(RCB4468) Inhibition of PSF Activity Overcomes Resistance to Treatment in Cancers Harboring Mutant p53.
Human and Animal Cells 32Dcl3(RCB1538) SBDS Gene Mutation Increases ROS Production and Causes DNA Damage as Well as Oxidation of Mitochondrial Membranes in the Murine Myeloid Cell Line 32Dcl3.
Human pathogenic viruses SA11 Generation of single-round infectious rotavirus with a mutation in the intermediate capsid protein VP6.
Human and Animal Cells HuCCT1(RCB1960) A base editing platform for the correction of cancer driver mutations unmasks conserved p53 transcription programs.
DNA material pTcf7wtluc (RDB02968) Basroparib overcomes acquired resistance to MEK inhibitors by inhibiting Wnt-mediated cancer stemness in KRAS-mutated colorectal cancer.