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  • Search Condition : Filter (MeSH = PTEN Phosphohydrolase / genetics)
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Human and Animal Cells JHOC-5(RCB1520) , JHOC-9(RCB2226) MicroRNA-21 is a candidate driver gene for 17q23-25 amplification in ovarian clear cell carcinoma.
Human and Animal Cells HuH-7 Downregulation of AZGP1 by Ikaros and histone deacetylase promotes tumor progression through the PTEN/Akt and CD44s pathways in hepatocellular carcinoma.
Human and Animal Cells JHOC-5(RCB1520) A functional proteogenomic analysis of endometrioid and clear cell carcinomas using reverse phase protein array and mutation analysis: protein expression is histotype-specific and loss of ARID1A/BAF250a is associated with AKT phosphorylation.
Drosophila DGRC#140400 Functional assessment of the "two-hit" model for neurodevelopmental defects in Drosophila and X. laevis.
Human and Animal Cells RAW 264(RCB0535) Tithonia diversifolia-derived orizabin suppresses cell adhesion, differentiation, and oxidized LDL accumulation by Akt signaling suppression via PTEN promotion in THP-1 cells.
Human and Animal Cells Ca9-22(RCB1976) , HSC-2(RCB1945) , HSC-4(RCB1902) , Sa3(RCB0980) , HSQ-89(RCB0789) , SAS(RCB1974) , HO-1-u-1(RCB2102) Loss of NDRG2 Expression Confers Oral Squamous Cell Carcinoma with Enhanced Metastatic Potential.
Drosophila 6987R-2 , 6987R-5 The Splicing Factor SF2 Is Critical for Hyperproliferation and Survival in a TORC1-Dependent Model of Early Tumorigenesis in Drosophila.
Human and Animal Cells HGC-27(RCB0500) CagA increases DNA methylation and decreases PTEN expression in human gastric cancer.
C.elegans tm1049 KIN-4/MAST kinase promotes PTEN-mediated longevity of Caenorhabditis elegans via binding through a PDZ domain.
Human and Animal Cells DU145(RCB2143) , PC-3(RCB2145) , 293(RCB1637) , LNCap.FGC(RCB2144) Increased fatty acyl saturation of phosphatidylinositol phosphates in prostate cancer progression.
Human and Animal Cells 10T1/2(RCB0247) TRPC6 regulates phenotypic switching of vascular smooth muscle cells through plasma membrane potential-dependent coupling with PTEN.
C.elegans tm1944 , tm1231 , tm1941 AMPK blocks starvation-inducible transgenerational defects in Caenorhabditis elegans.
Human and Animal Cells MKN1(RCB1003) , MKN45(RCB1001) , MKN7(RCB0999) , MKN74(RCB1002) PTEN loss is associated with a poor response to trastuzumab in HER2-overexpressing gastroesophageal adenocarcinoma.
C.elegans tm1944 DAF-18/PTEN signals through AAK-1/AMPK to inhibit MPK-1/MAPK in feedback control of germline stem cell proliferation.
Mice RBRC02300 Regulation of RhoA by STAT3 coordinates glial scar formation.
Human and Animal Cells EoL-1 cell(RCB0641) Tetraspanin Family Member, CD82, Regulates Expression of EZH2 via Inactivation of p38 MAPK Signaling in Leukemia Cells.
Human and Animal Cells HHUA(RCB0658) Anti-tumor activity of olaparib, a poly (ADP-ribose) polymerase (PARP) inhibitor, in cultured endometrial carcinoma cells.
Human and Animal Cells KLM-1(RCB2138) , PK-45P(RCB2141) , SAS(RCB1974) , HO-1-u-1(RCB2102) , Ca9-22(RCB1976) , HSC-2(RCB1945) , HSC-3(RCB1975) , HSC-4(RCB1902) , Sa3(RCB0980) , HeLa , ... Loss of NDRG2 expression activates PI3K-AKT signalling via PTEN phosphorylation in ATLL and other cancers.
Human and Animal Cells JHUEM-3(RCB1552) PI3K pathway dependencies in endometrioid endometrial cancer cell lines.
Human and Animal Cells HHUA(RCB0658) CCNE1 amplification is associated with aggressive potential in endometrioid endometrial carcinomas.