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  • Search Condition : Filter (MeSH = PTEN Phosphohydrolase / genetics)
Species Resource
Human and Animal Cells HGC-27(RCB0500) CagA increases DNA methylation and decreases PTEN expression in human gastric cancer.
C.elegans tm1944 , tm1231 , tm1941 AMPK blocks starvation-inducible transgenerational defects in Caenorhabditis elegans.
Human and Animal Cells MKN1(RCB1003) , MKN45(RCB1001) , MKN7(RCB0999) , MKN74(RCB1002) PTEN loss is associated with a poor response to trastuzumab in HER2-overexpressing gastroesophageal adenocarcinoma.
C.elegans tm1944 DAF-18/PTEN signals through AAK-1/AMPK to inhibit MPK-1/MAPK in feedback control of germline stem cell proliferation.
Mice B6.129P2-Pten<tm2Mak>(RBRC02300) Regulation of RhoA by STAT3 coordinates glial scar formation.
Human and Animal Cells Tetraspanin Family Member, CD82, Regulates Expression of EZH2 via Inactivation of p38 MAPK Signaling in Leukemia Cells.
Human and Animal Cells Anti-tumor activity of olaparib, a poly (ADP-ribose) polymerase (PARP) inhibitor, in cultured endometrial carcinoma cells.
Human and Animal Cells Loss of NDRG2 expression activates PI3K-AKT signalling via PTEN phosphorylation in ATLL and other cancers.
Human and Animal Cells PI3K pathway dependencies in endometrioid endometrial cancer cell lines.
Human and Animal Cells CCNE1 amplification is associated with aggressive potential in endometrioid endometrial carcinomas.
Human and Animal Cells PTEN and TRP53 independently suppress Nanog expression in spermatogonial stem cells.
Human and Animal Cells The oncogenic mutation in the pleckstrin homology domain of AKT1 in endometrial carcinomas.
Human and Animal Cells Aberrant overexpression of microRNAs activate AKT signaling via down-regulation of tumor suppressors in natural killer-cell lymphoma/leukemia.
Mice TOP-GAL(RBRC02228) Differential requirements for β-catenin in murine prostate cancer originating from basal versus luminal cells.
Cellular slime molds G90118 PTEN is a mechanosensing signal transducer for myosin II localization in Dictyostelium cells.
Arabidopsis / Cultured plant cells, genes pda06177 A novel class of PTEN protein in Arabidopsis displays unusual phosphoinositide phosphatase activity and efficiently binds phosphatidic acid.
DNA material , Human and Animal Cells AxCAhPTEN1 (RDB02012) , 293 (RCB1637) PTEN reduces cuff-induced neointima formation and proinflammatory cytokines.
Cellular slime molds G21638 , S00405 , S00406 , S90292 Chemotaxis in the absence of PIP3 gradients.
DNA material AxCAhPTEN1 (RDB02012) , AxCALacZ (RDB01745). Suppression of PTEN expression during aggregation with retinoic acid in P19 mouse embryonal carcinoma cells.
DNA material pAxCAhPTEN1(RDB02013) Transduction of phosphatase and tensin homolog deleted on chromosome 10 into eosinophils attenuates survival, chemotaxis, and airway inflammation.