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  • Search Condition : Filter (MeSH = Phagosomes / genetics)
Species Resource Title
DNA material pEGFP-C1-hATG2A (RDB19631) Mammalian Atg2 proteins are essential for autophagosome formation and important for regulation of size and distribution of lipid droplets.
Human and Animal Cells Rat-1(RCB1830) , HeLa(RCB0007) , MCF7(RCB1904) , Atg5^(+/+)MEF(RCB2710) , Atg5^(-/-)MEF(RCB2711) Detection of WIPI1 mRNA as an indicator of autophagosome formation.
Human and Animal Cells Atg5^(+/+)MEF(RCB2710) , Atg5^(-/-)MEF(RCB2711) Autophagosomal IkappaB alpha degradation plays a role in the long term control of tumor necrosis factor-alpha-induced nuclear factor-kappaB (NF-kappaB) activity.
C.elegans tm2058 , tm2790 , tm2640 , tm3628 , tm3630 , tm2564 , tm1865 , tm2907 The small GTPase RAB-35 defines a third pathway that is required for the recognition and degradation of apoptotic cells.
C.elegans tm2214 , tm2423 EFF-1 fusogen promotes phagosome sealing during cell process clearance in Caenorhabditis elegans.
Mice RBRC03941 Sqstm1-GFP knock-in mice reveal dynamic actions of Sqstm1 during autophagy and under stress conditions in living cells.
C.elegans tm2078 , tm2095 Residual body removal during spermatogenesis in C. elegans requires genes that mediate cell corpse clearance.
C.elegans tm3948 , tm3425 Autophagy genes coordinate with the class II PI/PtdIns 3-kinase PIKI-1 to regulate apoptotic cell clearance in C. elegans.
C.elegans tm2423 , tm1125 Clathrin and AP2 are required for phagocytic receptor-mediated apoptotic cell clearance in Caenorhabditis elegans.
DNA material GNP Clone , IRAK141K24 (HGX056664). Diacylglycerol kinases terminate diacylglycerol signaling during the respiratory burst leading to heterogeneous phagosomal NADPH oxidase activation.
Mice RBRC00806 The regulation of autophagosome dynamics by huntingtin and HAP1 is disrupted by expression of mutant huntingtin, leading to defective cargo degradation.
Drosophila GFP-IR-1 , UAS-Eater IR Genetic ablation of Drosophila phagocytes reveals their contribution to both development and resistance to bacterial infection.
Mice RBRC00806 The drs tumor suppressor is involved in the maturation process of autophagy induced by low serum.