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  • 検索条件 : 絞込み (MeSH = Phosphoinositide-3 Kinase Inhibitors)
生物種 リソース名 タイトル
遺伝子材料 pEGFP-C1-hUVRAG (RDB19632) , pMXs-puro-VPS34-GFP (RDB19633) , p3xFLAG-CMV10-hUVRAG (RDB19776) , pEGFP-C1-hAtg14 (RDB19785) , pMXs-IP-GFP-Atg14 (RDB19790) , pCI-neo-HA-hAtg14 (RDB19797) , pCI-neo-HA-hUVRAG (RDB19803) Beclin 1 forms two distinct phosphatidylinositol 3-kinase complexes with mammalian Atg14 and UVRAG.
ヒト・動物細胞 L929 Rac is activated by tumor necrosis factor alpha and is involved in activation of Erk.
ヒト・動物細胞 A549 Increase in Anticancer Drug-Induced Toxicity by Fisetin in Lung Adenocarcinoma A549 Spheroid Cells Mediated by the Reduction of Claudin-2 Expression.
ヒト・動物細胞 LM8(RCB1450) Reduction of metastasis, cell invasion, and adhesion in mouse osteosarcoma by YM529/ONO-5920-induced blockade of the Ras/MEK/ERK and Ras/PI3K/Akt pathway.
ヒト・動物細胞 MDCK(RCB0995) Leader cells regulate collective cell migration via Rac activation in the downstream signaling of integrin β1 and PI3K.
ヒト・動物細胞 JHOM-1(RCB1676) , JHOM-2B(RCB1682) , OMC-3(RCB0755) Synergistic antitumor effects of combination PI3K/mTOR and MEK inhibition (SAR245409 and pimasertib) in mucinous ovarian carcinoma cells by fluorescence resonance energy transfer imaging.
ヒト・動物細胞 ATDC5(RCB0565) Involvement of the phosphoinositide 3-kinase/protein kinase B signaling pathway in insulin/IGF-I-induced chondrogenesis of the mouse embryonal carcinoma-derived cell line ATDC5.
ヒト・動物細胞 RAW 264(RCB0535) Involvement of interleukin‑23 induced by Porphyromonas endodontalis lipopolysaccharide in osteoclastogenesis.
ヒト・動物細胞 A172(RCB2530) Crosstalk between the PI3K/mTOR and MEK/ERK pathways involved in the maintenance of self-renewal and tumorigenicity of glioblastoma stem-like cells.
ヒト・動物細胞 JHUEM-2(RCB1551) PI3K Inhibitors Synergize with FGFR Inhibitors to Enhance Antitumor Responses in FGFR2mutant Endometrial Cancers.
ヒト・動物細胞 HHUA(RCB0658) Lipocalin 2 Enhances Migration and Resistance against Cisplatin in Endometrial Carcinoma Cells.
ヒト・動物細胞 RERF-LC-AI(RCB0444) , IA-LM(RCB0554) , WA-hT(RCB2279) Claudin-18 inhibits cell proliferation and motility mediated by inhibition of phosphorylation of PDK1 and Akt in human lung adenocarcinoma A549 cells.
線虫 tm1888 Insulin/IGF-1 signaling, including class II/III PI3Ks, β-arrestin and SGK-1, is required in C. elegans to maintain pharyngeal muscle performance during starvation.
ヒト・動物細胞 409B2(HPS0076) Examination of a Viral Infection Mimetic Model in Human iPS Cell-Derived Insulin-Producing Cells and the Anti-Apoptotic Effect of GLP-1 Analogue.
ヒト・動物細胞 MG6(RCB2403) Acidic pH increases cGMP accumulation through the OGR1/phospholipase C/Ca(2+)/neuronal NOS pathway in N1E-115 neuronal cells.
ヒト・動物細胞 RAW 264(RCB0535) , CACO-2(RCB0988) Exhaustive exercise increases the TNF-α production in response to flagellin via the upregulation of toll-like receptor 5 in the large intestine in mice.
ヒト・動物細胞 JHUEM-3(RCB1552) PI3K pathway dependencies in endometrioid endometrial cancer cell lines.
ヒト・動物細胞 StromaNKtert(RCB2350) Decreased mitochondrial apoptotic priming underlies stroma-mediated treatment resistance in chronic lymphocytic leukemia.
ヒト・動物細胞 IEC 6(RCB0993) Ginsenoside Rd prevents and rescues rat intestinal epithelial cells from irradiation-induced apoptosis.
ヒト・動物細胞 KU812(RCB0495) Role of thrombin in interleukin-5 expression from basophils.