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  • 検索条件 : 絞込み (MeSH = Piperazines / pharmacology)
生物種 リソース名 タイトル
ヒト・動物細胞 MIA Paca2(RCB2094) , LU65(RCB1967) Characterisation of a novel KRAS G12C inhibitor ASP2453 that shows potent anti-tumour activity in KRAS G12C-mutated preclinical models.
ヒト・動物細胞 MC3T3-E1(RCB1126) Bone Formation Ability and Cell Viability Enhancement of MC3T3-E1 Cells by Ferrostatin-1 a Ferroptosis Inhibitor of Cancer Cells.
ヒト・動物細胞 HeLa(RCB0007) Mitotic specific phosphorylation of serine-1212 in human DNA topoisomerase IIalpha.
ヒト・動物細胞 B16F10(RCB2630) Sorafenib fails to trigger ferroptosis across a wide range of cancer cell lines.
ヒト・動物細胞 JHOC-5(RCB1520) Inhibition of the MYC-Regulated Glutaminase Metabolic Axis Is an Effective Synthetic Lethal Approach for Treating Chemoresistant Ovarian Cancers.
ヒト・動物細胞 TEN(RCB1433) The efficacy of the cyclin-dependent kinase 4/6 inhibitor in endometrial cancer.
ヒト・動物細胞 HSC-2(RCB1945) , Ca9-22(RCB1976) , SAS(RCB1974) Synergetic Effects of PARP Inhibitor AZD2281 and Cisplatin in Oral Squamous Cell Carcinoma in Vitro and in Vivo.
ヒト・動物細胞 KLM-1(RCB2138) Combining the antimesothelin immunotoxin SS1P with the BH3-mimetic ABT-737 induces cell death in SS1P-resistant pancreatic cancer cells.
ヒト・動物細胞 ACC-MESO-1(RCB2292) , ACC-MESO-4(RCB2293) Combined use of irinotecan and p53 activator enhances growth inhibition of mesothelioma cells.
ヒト・動物細胞 PANC-1(RCB2095) Selective cytotoxicity of marine-derived fungal metabolite (3S,6S)-3,6-dibenzylpiperazine-2,5-dione against cancer cells adapted to nutrient starvation.
ヒト・動物細胞 10T1/2(RCB0247) Runx2 is required for the proliferation of osteoblast progenitors and induces proliferation by regulating Fgfr2 and Fgfr3.
ヒト・動物細胞 JHOC-7(RCB1688) Anti-tumor activity of dual inhibition of phosphatidylinositol 3-kinase and MDM2 against clear cell ovarian carcinoma.
ヒト・動物細胞 Hep G2 Human alcohol dehydrogenase 1 is an acceptor protein for polyADP-ribosylation.
ヒト・動物細胞 Ba/F3(RCB0805) Dual blockade of EGFR tyrosine kinase using osimertinib and afatinib eradicates EGFR‑mutant Ba/F3 cells.
ヒト・動物細胞 PANC-1(RCB2095) Inhibition of ERK1/2 in cancer-associated pancreatic stellate cells suppresses cancer-stromal interaction and metastasis.
遺伝子材料 pENTER-EGFR wild-type (RDB15488) , pENTER-EGFR Del19 (RDB15489) , pENTER-EGFR T790M/del19 (RDB15490) , pENTER-EGFR C797S/del19 (RDB15491) , pENTER-EGFR C797S/T790M/del19 (RDB15492) , pENTER-EGFR L858R (RDB15493) , pENTER-EGFR T790M/L858R (RDB15494) , pENTER-EGFR C797S/L858R (RDB15495) , pENTER-EGFR C797S/T790M/L858R (RDB15496). Brigatinib combined with anti-EGFR antibody overcomes osimertinib resistance in EGFR-mutated non-small-cell lung cancer.
遺伝子材料 R1 B - R1G (RDB13204) Structures and properties of seven isoforms of the NMDA receptor generated by alternative splicing.
ヒト・動物細胞 RAW 264(RCB0535) Lipopolysaccharide downregulates the expression of p53 through activation of MDM2 and enhances activation of nuclear factor-kappa B.
ヒト・動物細胞 K562 Inhibition of the PI3K/Akt/GSK3 pathway downstream of BCR/ABL, Jak2-V617F, or FLT3-ITD downregulates DNA damage-induced Chk1 activation as well as G2/M arrest and prominently enhances induction of apoptosis.
ヒト・動物細胞 PCM6(RCB1460) Bortezomib reduces the tumorigenicity of multiple myeloma via downregulation of upregulated targets in clonogenic side population cells.