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  • Search Condition : Filter (MeSH = Piperazines / pharmacology)
Species Resource Title
Human and Animal Cells 10T1/2(RCB0247) Runx2 is required for the proliferation of osteoblast progenitors and induces proliferation by regulating Fgfr2 and Fgfr3.
Human and Animal Cells JHOC-7(RCB1688) Anti-tumor activity of dual inhibition of phosphatidylinositol 3-kinase and MDM2 against clear cell ovarian carcinoma.
Human and Animal Cells HepG2 Human alcohol dehydrogenase 1 is an acceptor protein for polyADP-ribosylation.
Human and Animal Cells Ba/F3(RCB0805) Dual blockade of EGFR tyrosine kinase using osimertinib and afatinib eradicates EGFR‑mutant Ba/F3 cells.
Human and Animal Cells PANC-1(RCB2095) Inhibition of ERK1/2 in cancer-associated pancreatic stellate cells suppresses cancer-stromal interaction and metastasis.
DNA material pENTER-EGFR wild-type (RDB15488) , pENTER-EGFR Del19 (RDB15489) , pENTER-EGFR T790M/del19 (RDB15490) , pENTER-EGFR C797S/del19 (RDB15491) , pENTER-EGFR C797S/T790M/del19 (RDB15492) , pENTER-EGFR L858R (RDB15493) , pENTER-EGFR T790M/L858R (RDB15494) , pENTER-EGFR C797S/L858R (RDB15495) , pENTER-EGFR C797S/T790M/L858R (RDB15496). Brigatinib combined with anti-EGFR antibody overcomes osimertinib resistance in EGFR-mutated non-small-cell lung cancer.
DNA material R1 B - R1G (RDB13204) Structures and properties of seven isoforms of the NMDA receptor generated by alternative splicing.
Human and Animal Cells Lipopolysaccharide downregulates the expression of p53 through activation of MDM2 and enhances activation of nuclear factor-kappa B.
Human and Animal Cells Inhibition of the PI3K/Akt/GSK3 pathway downstream of BCR/ABL, Jak2-V617F, or FLT3-ITD downregulates DNA damage-induced Chk1 activation as well as G2/M arrest and prominently enhances induction of apoptosis.
Human and Animal Cells Bortezomib reduces the tumorigenicity of multiple myeloma via downregulation of upregulated targets in clonogenic side population cells.
Human and Animal Cells Potentiation of nerve growth factor-induced neurite outgrowth by fluvoxamine: role of sigma-1 receptors, IP3 receptors and cellular signaling pathways.
Human and Animal Cells Mechanisms for the proliferation of eosinophilic leukemia cells by FIP1L1-PDGFRalpha.
Human and Animal Cells The inhibitory effects of fluoroquinolones on L-carnitine transport in placental cell line BeWo.
Human and Animal Cells Uptake of the dopaminergic neurotoxin, norsalsolinol, into PC12 cells via dopamine transporter.
Human and Animal Cells Dynamics of chromosomes and microtubules visualized by multiple-wavelength fluorescence imaging in living mammalian cells: effects of mitotic inhibitors on cell cycle progression.
Human and Animal Cells Sorafenib induces apoptosis specifically in cells expressing BCR/ABL by inhibiting its kinase activity to activate the intrinsic mitochondrial pathway.
Human and Animal Cells Sensitivity of SNX2-ABL1 toward tyrosine kinase inhibitors distinct from that of BCR-ABL1.
Human and Animal Cells Potentiation of neurite outgrowth by brexpiprazole, a novel serotonin-dopamine activity modulator: a role for serotonin 5-HT1A and 5-HT2A receptors.
Mice B6;129-Grn<tm1>(RBRC02370) Progranulin promotes the retinal precursor cell proliferation and the photoreceptor differentiation in the mouse retina.
DNA material pMSCVneo-MEF2C (RDB13695) BCL2 Inhibitor (ABT-737): A Restorer of Prednisolone Sensitivity in Early T-Cell Precursor-Acute Lymphoblastic Leukemia with High MEF2C Expression?