生物種
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リソース名
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RRC ID
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タイトル
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ジャーナル
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公開日
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外部リンク
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ヒト・動物細胞
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Hep G2(RCB1648)
,
Hep G2(RCB1886)
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70114
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Association between in vitro nuclear receptor-activating profiles of chemical compounds and their in vivo hepatotoxicity in rats.
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J Toxicol Sci |
2021-1-1 |
Pubmed
Full text
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ヒト・動物細胞
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Hep G2
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68507
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Characterization of six base pair deletion in the putative HNF1-binding site of human PXR promoter.
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J Hum Genet |
2003-1-1 |
Pubmed
Full text
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ヒト・動物細胞
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Hep G2(RCB1886)
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56005
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Effects of Vitamin K₂ on the Expression of Genes Involved in Bile Acid Synthesis and Glucose Homeostasis in Mice with Humanized PXR.
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Nutrients |
2018-7-27 |
Pubmed
Full text
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ヒト・動物細胞
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Hep G2
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55993
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Acceleration of murine hepatocyte proliferation by imazalil through the activation of nuclear receptor PXR.
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J Toxicol Sci |
2018-1-1 |
Pubmed
Full text
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ヒト・動物細胞
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COS-1(RCB0143)
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51872
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Metabolism of methiocarb and carbaryl by rat and human livers and plasma, and effect on their PXR, CAR and PPARα activities.
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J Toxicol Sci |
2016-1-1 |
Pubmed
Full text
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ヒト・動物細胞
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Hep G2(RCB1886)
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51604
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Indirubin, a component of Ban-Lan-Gen, activates CYP3A4 gene transcription through the human pregnane X receptor.
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Drug Metab Pharmacokinet |
2016-4-1 |
Pubmed
Full text
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ヒト・動物細胞
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|
45206
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Threonine-290 regulates nuclear translocation of the human pregnane X receptor through its phosphorylation/dephosphorylation by Ca2+/calmodulin-dependent protein kinase II and protein phosphatase 1.
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Drug Metab Dispos |
2014-10-1 |
Pubmed
Full text
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ヒト・動物細胞
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CV-1(RCB0160)
,
Hep G2
|
44049
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Identification of endocrine disrupting chemicals activating SXR-mediated transactivation of CYP3A and CYP7A1.
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Mol Cell Endocrinol |
2013-1-5 |
Pubmed
Full text
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ヒト・動物細胞
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Hep G2
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43972
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Regulation of pregnane X receptor (PXR) function and UGT1A1 gene expression by posttranslational modification of PXR protein.
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Drug Metab Dispos |
2012-10-1 |
Pubmed
Full text
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ヒト・動物細胞
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Hep G2
,
HuH-7(RCB1366)
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43270
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Post-transcriptional regulation of human pregnane X receptor by micro-RNA affects the expression of cytochrome P450 3A4.
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J Biol Chem |
2008-4-11 |
Pubmed
Full text
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ヒト・動物細胞
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Hep G2(RCB1648)
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42530
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Regulation of the human UGT1A1 gene by nuclear receptors constitutive active/androstane receptor, pregnane X receptor, and glucocorticoid receptor.
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Methods Enzymol |
2005-1-1 |
Pubmed
Full text
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ヒト・動物細胞
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CACO-2(RCB0988)
,
Hep G2(RCB1648)
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42141
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The induction of human UDP-glucuronosyltransferase 1A1 mediated through a distal enhancer module by flavonoids and xenobiotics.
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Biochem Pharmacol |
2004-3-1 |
Pubmed
Full text
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ヒト・動物細胞
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293(RCB1637)
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38900
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PXR stimulates growth factor-mediated hepatocyte proliferation by cross-talk with the FOXO transcription factor.
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Biochem J |
2016-2-1 |
Pubmed
Full text
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ヒト・動物細胞
|
|
38538
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Transactivation of ABCG2 through a novel cis-element in the distal promoter by constitutive androstane receptor but not pregnane X receptor in human hepatocytes.
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Arch Biochem Biophys |
2012-1-15 |
Pubmed
Full text
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ヒト・動物細胞
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CACO-2(RCB0988)
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38246
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Induction of UGT1A1 and CYP2B6 by an antimitogenic factor in HepG2 cells is mediated through suppression of cyclin-dependent kinase 2 activity: cell cycle-dependent expression.
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Drug Metab Dispos |
2010-1-1 |
Pubmed
Full text
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ヒト・動物細胞
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EC-GI-10(RCB0774)
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38231
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Steroid and xenobiotic receptor in human esophageal squamous cell carcinoma: a potent prognostic factor.
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Cancer Sci |
2010-2-1 |
Pubmed
Full text
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ヒト・動物細胞
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ATDC5(RCB0565)
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36912
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Pregnane X receptor knockout mice display aging-dependent wearing of articular cartilage.
|
PLoS One |
2015-1-1 |
Pubmed
Full text
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ヒト・動物細胞
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HOS(RCB0992)
,
Saos-2(RCB0428)
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18924
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Inhibitory effect of vitamin K(2) on interleukin-1beta-stimulated proliferation of human osteoblasts.
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Biol Pharm Bull |
2010-1-1 |
Pubmed
Full text
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メダカ
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database
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15500
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The evolution of farnesoid X, vitamin D, and pregnane X receptors: insights from the green-spotted pufferfish (Tetraodon nigriviridis) and other non-mammalian species.
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BMC Biochem |
2011-2-3 |
Pubmed
Full text
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遺伝子材料
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AxCALacZ Adex1CAlacZ (RDB02726)
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11961
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Differentiation of mouse hepatic progenitor cells induced by hepatocyte nuclear factor-4 and cell transplantation in mice with liver fibrosis.
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Transplantation |
2008-11-15 |
Pubmed
Full text
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