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  • Search Condition : Filter (MeSH = Pregnane X Receptor)
Species Resource Title
C.elegans tm1800 Pregnane X receptor agonist nomilin extends lifespan and healthspan in preclinical models through detoxification functions.
Human and Animal Cells HuH-7(RCB1366) Vitamin K2 suppresses proliferation and motility of hepatocellular carcinoma cells by activating steroid and xenobiotic receptor.
Human and Animal Cells Hep G2(RCB1648) , Hep G2(RCB1886) Association between in vitro nuclear receptor-activating profiles of chemical compounds and their in vivo hepatotoxicity in rats.
Human and Animal Cells Hep G2 Characterization of six base pair deletion in the putative HNF1-binding site of human PXR promoter.
Human and Animal Cells Hep G2(RCB1886) Effects of Vitamin K₂ on the Expression of Genes Involved in Bile Acid Synthesis and Glucose Homeostasis in Mice with Humanized PXR.
Human and Animal Cells Hep G2 Acceleration of murine hepatocyte proliferation by imazalil through the activation of nuclear receptor PXR.
Human and Animal Cells COS-1(RCB0143) Metabolism of methiocarb and carbaryl by rat and human livers and plasma, and effect on their PXR, CAR and PPARα activities.
Human and Animal Cells Hep G2(RCB1886) Indirubin, a component of Ban-Lan-Gen, activates CYP3A4 gene transcription through the human pregnane X receptor.
Human and Animal Cells CV-1(RCB0160) , Hep G2 Identification of endocrine disrupting chemicals activating SXR-mediated transactivation of CYP3A and CYP7A1.
Human and Animal Cells Hep G2 Regulation of pregnane X receptor (PXR) function and UGT1A1 gene expression by posttranslational modification of PXR protein.
Human and Animal Cells Hep G2 , HuH-7(RCB1366) Post-transcriptional regulation of human pregnane X receptor by micro-RNA affects the expression of cytochrome P450 3A4.
Human and Animal Cells Hep G2(RCB1648) Regulation of the human UGT1A1 gene by nuclear receptors constitutive active/androstane receptor, pregnane X receptor, and glucocorticoid receptor.
Human and Animal Cells CACO-2(RCB0988) , Hep G2(RCB1648) The induction of human UDP-glucuronosyltransferase 1A1 mediated through a distal enhancer module by flavonoids and xenobiotics.
Human and Animal Cells 293(RCB1637) PXR stimulates growth factor-mediated hepatocyte proliferation by cross-talk with the FOXO transcription factor.
Human and Animal Cells Transactivation of ABCG2 through a novel cis-element in the distal promoter by constitutive androstane receptor but not pregnane X receptor in human hepatocytes.
Human and Animal Cells CACO-2(RCB0988) Induction of UGT1A1 and CYP2B6 by an antimitogenic factor in HepG2 cells is mediated through suppression of cyclin-dependent kinase 2 activity: cell cycle-dependent expression.
Human and Animal Cells EC-GI-10(RCB0774) Steroid and xenobiotic receptor in human esophageal squamous cell carcinoma: a potent prognostic factor.
Human and Animal Cells ATDC5(RCB0565) Pregnane X receptor knockout mice display aging-dependent wearing of articular cartilage.
Human and Animal Cells HOS(RCB0992) , Saos-2(RCB0428) Inhibitory effect of vitamin K(2) on interleukin-1beta-stimulated proliferation of human osteoblasts.
Medaka database The evolution of farnesoid X, vitamin D, and pregnane X receptors: insights from the green-spotted pufferfish (Tetraodon nigriviridis) and other non-mammalian species.