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  • 114 Hits
  • Search Condition : Filter (MeSH = Protein Kinase Inhibitors / pharmacology)
Species Resource Title
Human and Animal Cells TGBC1TKB(RCB1129) Preclinical activity of EGFR and MEK1/2 inhibitors in the treatment of biliary tract carcinoma.
Human and Animal Cells K562(RCB1897) Co-activation of WT1 and AP-1 proteins on WT1 gene promoter to induce WT1 gene expression in K562 cells.
Human and Animal Cells DJM-1(RCB0736) , A431(RCB0202) Tamoxifen inhibits the proliferation of non‑melanoma skin cancer cells by increasing intracellular calcium concentration.
Human and Animal Cells PC-9(RCB4455) Osimertinib Overcomes Alectinib Resistance Caused by Amphiregulin in a Leptomeningeal Carcinomatosis Model of ALK-Rearranged Lung Cancer.
Human and Animal Cells HL60(RCB0041) , U-937 DE-4(RCB0435) Nitrogen-containing bisphosphonates induce apoptosis of hematopoietic tumor cells via inhibition of Ras signaling pathways and Bim-mediated activation of the intrinsic apoptotic pathway.
Human and Animal Cells Ba/F3(RCB0805) Emergence of CTNNB1 mutation at acquired resistance to KIT inhibitor in metastatic melanoma.
Human and Animal Cells MC3T3-E1(MC3T3-E1) Elevated expression of CTRP3/cartducin contributes to promotion of osteosarcoma cell proliferation.
Human and Animal Cells ST2(RCB0224) Bisphosphonate- and statin-induced enhancement of OPG expression and inhibition of CD9, M-CSF, and RANKL expressions via inhibition of the Ras/MEK/ERK pathway and activation of p38MAPK in mouse bone marrow stromal cell line ST2.
Human and Animal Cells CACO-2(RCB0988) Antitumor activity of the selective ALK inhibitor alectinib in models of intracranial metastases.
Human and Animal Cells ST2(RCB0224) RANKL-induced c-Src activation contributes to conventional anti-cancer drug resistance and dasatinib overcomes this resistance in RANK-expressing multiple myeloma cells.
Zebrafish s357 Identification of pathways that regulate circadian rhythms using a larval zebrafish small molecule screen.
Human and Animal Cells HCT116(RCB2979), MKN45(RCB1001) Inhibition of AURKA Reduces Proliferation and Survival of Gastrointestinal Cancer Cells With Activated KRAS by Preventing Activation of RPS6KB1.
Human and Animal Cells JHOC-7(RCB1688) Anti-tumor activity of dual inhibition of phosphatidylinositol 3-kinase and MDM2 against clear cell ovarian carcinoma.
Human and Animal Cells PC-9(RCB4455) Effect of platinum‑based chemotherapy on the expression of natural killer group 2 member D ligands, programmed cell death‑1 ligand 1 and HLA class I in non‑small cell lung cancer.
Human and Animal Cells A549 ZO-2 Suppresses Cell Migration Mediated by a Reduction in Matrix Metalloproteinase 2 in Claudin-18-Expressing Lung Adenocarcinoma A549 Cells.
Human and Animal Cells NRK49F(RCB0112) The signal pathway for the repressive effect of dipyridamole on myofibroblast transdifferentiation.
Human and Animal Cells 3T3 L1(RCB1643) (-)-O-Methylcubebin from Vitex trifolia Enhanced Adipogenesis in 3T3-L1 Cells via the Inhibition of ERK1/2 and p38MAPK Phosphorylation.
Human and Animal Cells KG-1(RCB1166) Activation of PKC induces leukocyte adhesion by the dephosphorylation of ERM.
Human and Animal Cells CW-2(RCB0778) Pan-Cancer Landscape and Analysis of ERBB2 Mutations Identifies Poziotinib as a Clinically Active Inhibitor and Enhancer of T-DM1 Activity.
Human and Animal Cells KP4(RCB1005) Synthetic Lethal Interaction of SHOC2 Depletion with MEK Inhibition in RAS-Driven Cancers.