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  • 92 Hits
  • Search Condition : Filter (MeSH = Protein Kinase Inhibitors / pharmacology)
Species Resource
Human embryonic stem cells KhES-1 , KhES-3 Defining early lineage specification of human embryonic stem cells by the orchestrated balance of canonical Wnt/beta-catenin, Activin/Nodal and BMP signaling.
Yeast NA Comprehensive screening of human genes with inhibitory effects on yeast growth and validation of a yeast cell-based system for screening chemicals.
DNA material pRx nZ ires Neo (RDB01699). Proliferation and survival signaling from both Jak2-V617F and Lyn involving GSK3 and mTOR/p70S6K/4EBP1 in PVTL-1 cell line newly established from acute myeloid leukemia transformed from polycythemia vera.
Mice B6.Cg-Tg(CAG-Cre)CZ-MO2Osb(RBRC01828) New BRAF knockin mice provide a pathogenetic mechanism of developmental defects and a therapeutic approach in cardio-facio-cutaneous syndrome.
Zebrafish Tg(6xTcf/LefBS-miniP:d2EGFP)/isi01 ErbB expressing Schwann cells control lateral line progenitor cells via non-cell-autonomous regulation of Wnt/β-catenin.
DNA material CSII-EF-MCS-IRES2-Venus (RDB04384) , pCMV-VSV-G-RSV-Rev (RDB04393). Bruton's tyrosine kinase is essential for NLRP3 inflammasome activation and contributes to ischaemic brain injury.
Mice B6;129-Ace3<tm1Osb>(RBRC04138) Angiotensin-Converting Enzyme 3 (ACE3) Protects Against Pressure Overload-Induced Cardiac Hypertrophy.
DNA material human MLC20 WT (RDB14158) , human MLC20 T18A (RDB14159) , human MLC20 S19A (RDB14160) , human MLC20 T18A+S19A (RDB14161). Myosin di-phosphorylation and peripheral actin bundle formation as initial events during endothelial barrier disruption.
DNA material pRSET-hp38 (RDB08172) , pRSET-hp38K53A (RDB08173) , pRSET-hp38T106M (RDB08174) , pRSET-GST-hp38 (RDB08178) A p38 mitogen-activated protein kinase inhibitor screening method using growth recovery of Escherichia coli as an index.
DNA material pBR-PyCAG-fSmad7DsRedT4-IPG (RDB10704) Activin-Nodal signaling is involved in propagation of mouse embryonic stem cells.
Human and Animal Cells THP-1 (RCB1189) Fluoroquinolones and propionic acid derivatives induce inflammatory responses in vitro.
Human and Animal Cells II-18(RCB2093) Glucose metabolism-targeted therapy and withaferin A are effective for epidermal growth factor receptor tyrosine kinase inhibitor-induced drug-tolerant persisters.
Human and Animal Cells MRC-5(RCB0211) Resistance mediated by alternative receptor tyrosine kinases in FGFR1-amplified lung cancer.
Human and Animal Cells GE1(RCB1709) IL-1β and TNF-α regulate mouse amelotin gene transcription in gingival epithelial cells.
Human and Animal Cells Ba/F3(RCB0805) Effects of secondary EGFR mutations on resistance against upfront osimertinib in cells with EGFR-activating mutations in vitro.
Human and Animal Cells Involvement of β-adrenoceptors in the differentiation of human induced pluripotent stem cells into mesodermal progenitor cells.
Human and Animal Cells Lipopolysaccharide downregulates the expression of p53 through activation of MDM2 and enhances activation of nuclear factor-kappa B.
Human and Animal Cells Pathological roles of the VEGF/SphK pathway in Niemann-Pick type C neurons.
Human and Animal Cells Induction of neurite outgrowth in PC12 cells treated with temperature-controlled repeated thermal stimulation.
Human and Animal Cells HS-SY-II (RCB2231) Essential role of mitogen-activated protein kinases in IL-17A-induced MMP-3 expression in human synovial sarcoma cells.