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論文 - 一覧

  • 190 Hits
  • 検索条件 : 絞込み (MeSH = Protein Kinase Inhibitors / pharmacology)
生物種 リソース名 タイトル
ヒト・動物細胞 Ba/F3 Structural Optimization of Fibroblast Growth Factor Receptor Inhibitors for Treating Solid Tumors.
ヒト・動物細胞 NUGC-4(RCB1939) , MKN7(RCB0999) , MKN45(RCB1001) ARID1A deficiency is targetable by AKT inhibitors in HER2-negative gastric cancer.
ヒト・動物細胞 Ba/F3-CL1(RCB4474) Secondary Mutations of the EGFR Gene That Confer Resistance to Mobocertinib in EGFR Exon 20 Insertion.
ヒト・動物細胞 Li-7(RCB1941) WNTinib is a multi-kinase inhibitor with specificity against β-catenin mutant hepatocellular carcinoma.
ヒト・動物細胞 Ba/F3(RCB0805) The complexity of EGFR exon 19 deletion and L858R mutant cells as assessed by proteomics, transcriptomics, and metabolomics.
ヒト・動物細胞 JMSU1(RCB2227) Discovery of lirafugratinib (RLY-4008), a highly selective irreversible small-molecule inhibitor of FGFR2.
ヒト・動物細胞 EBC-1(RCB1965) Discovery of LAH-1 as potent c-Met inhibitor for the treatment of non-small cell lung cancer.
ヒト・動物細胞 Lu-134-A(RCB0466) , Lu-134-B(RCB0467) Targeting small cell lung cancer harboring PIK3CA mutation with a selective oral PI3K inhibitor PF-4989216.
ヒト・動物細胞 PK-45H(RCB1973) , PK-59(RCB1901) , MIA Paca2(RCB2094) , PANC-1(RCB2095) , PK-1(RCB972) Involvement of clusterin expression in the refractory response of pancreatic cancer cells to a MEK inhibitor.
ヒト・動物細胞 EoL-1 cell(RCB0641) p53 is critical for the Aurora B kinase inhibitor-mediated apoptosis in acute myelogenous leukemia cells.
ヒト・動物細胞 9-15C(RCB2323) A Novel Triple-Action Inhibitor Targeting B-Cell Receptor Signaling and BRD4 Demonstrates Preclinical Activity in Chronic Lymphocytic Leukemia.
ヒト・動物細胞 Ba/F3(RCB4476) , LC-2/ad(RCB0440) Vepafestinib is a pharmacologically advanced RET-selective inhibitor with high CNS penetration and inhibitory activity against RET solvent front mutations.
ヒト・動物細胞 , 遺伝子材料 II-18(RCB2093) , tFucci(CA)2/pCSII-EF (RDB15446) L858R emerges as a potential biomarker predicting response of lung cancer models to anti-EGFR antibodies: Comparison of osimertinib vs. cetuximab.
ヒト・動物細胞 Ba/F3(RCB0805) Molecular Mechanisms of Resistance to First- and Second-Generation ALK Inhibitors in ALK-Rearranged Lung Cancer.
ヒト・動物細胞 JMSU1(RCB2227) Fibroblast growth factor receptor inhibitor erdafitinib promotes Mcl-1 degradation and synergistically induces apoptosis with Bcl-xL/Bcl-2 inhibitor in urothelial cancer cells.
遺伝子材料 mVenus-hGeminin(1/110) / pCSII-EF (RDB15271) , mCherry-hCdt1(30/120)/ pCSII-EF (RDB15273) Bosutinib high density lipoprotein nanoformulation has potent tumour radiosensitisation effects.
ヒト・動物細胞 Rat-1(RCB1830) Targeting Poly(ADP)ribose polymerase in BCR/ABL1-positive cells.
ヒト・動物細胞 Ba/F3 NVL-520 Is a Selective, TRK-Sparing, and Brain-Penetrant Inhibitor of ROS1 Fusions and Secondary Resistance Mutations.
ヒト・動物細胞 LC-2/ad(RCB0440) Dual inhibition of BCL2L1 and MCL1 is highly effective against RET fusion-positive or MET exon 14 skipping mutation-positive lung adenocarcinoma cells.
ヒト・動物細胞 PC-9(RCB4455) Oncogenic epidermal growth factor receptor signal-induced histone deacetylation suppresses chemokine gene expression in human lung adenocarcinoma.