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論文 - 一覧

  • 209 Hits
  • 検索条件 : 絞込み (MeSH = Protein Kinase Inhibitors / pharmacology)
生物種 リソース名 タイトル
ショウジョウバエ Inhibition of NAD-GPx4 axis and MEK triggers ferroptosis to suppress pancreatic ductal adenocarcinoma.
ゼブラフィッシュ UAS:GFP Transforming growth factor-β receptor I kinase plays a crucial role in oligodendrocyte regeneration after demyelination.
ヒト・動物細胞 CW-2(RCB0778) Co-targeting KRASG12D and the HER family is efficacious in colorectal cancer.
ゼブラフィッシュ UAS:RFP Somatic RIT1 delins in arteriovenous malformations hyperactivate RAS-MAPK signaling amenable to MEK inhibition.
ヒト・動物細胞 A431(RCB0202) TNK2 Inhibitor (R)-9bMS Causes Polyploidization Through Mitotic Failure by Targeting Aurora B.
ヒト・動物細胞 NUGC-4(RCB1939) Characterization of MET Alterations in 37 Gastroesophageal Cancer Cell Lines for MET-Targeted Therapy.
遺伝子材料 miR-579/ZFR pGL3 (RDB20902) The MITF/mir-579-3p regulatory axis dictates BRAF-mutated melanoma cell fate in response to MAPK inhibitors.
遺伝子材料 tFucci(CA)2/pCSII-EF (RDB15446) A bispecific antibody targeting EGFR and AXL delays resistance to osimertinib.
ヒト・動物細胞 HL60(RCB0041) , U937 , Jurkat Hypoxia-inducible factor 1α inhibitor induces cell death via suppression of BCR-ABL1 and Met expression in BCR-ABL1 tyrosine kinase inhibitor sensitive and resistant chronic myeloid leukemia cells.
ヒト・動物細胞 TFK-1(RCB2537) SRPK Inhibitors Reduce the Phosphorylation and Translocation of SR Protein Splicing Factors, thereby Correcting BIN1, MCL-1 and BCL2 Splicing Errors and Enabling Apoptosis of Cholangiocarcinoma Cells.
遺伝子材料 CS-RfA-EG (RDB04391) , pCMV-VSV-G-RSV-Rev (RDB04393) , pCAG-HIVgp (RDB04394) Deubiquitylase USP25 prevents degradation of BCR-ABL protein and ensures proliferation of Ph-positive leukemia cells.
遺伝子材料 pCMV-VSV-G-RSV-Rev (RDB04393) , pCAG-HIVgp (RDB04394) The novel ZEB1-upregulated protein PRTG induced by Helicobacter pylori infection promotes gastric carcinogenesis through the cGMP/PKG signaling pathway.
ヒト・動物細胞 K562(RCB0027) Asciminib, a novel allosteric inhibitor of BCR-ABL1, shows synergistic effects when used in combination with imatinib with or without drug resistance.
ヒト・動物細胞 Ba/F3(RCB0805) , K562 FL118 Is a Potent Therapeutic Agent against Chronic Myeloid Leukemia Resistant to BCR-ABL Inhibitors through Targeting RNA Helicase DDX5.
ヒト・動物細胞 COLO-320(RCB1193) Inhibition of insulin-like growth factor-1 receptor enhances eribulin-induced DNA damage in colorectal cancer.
ヒト・動物細胞 RBE(RCB1292) EGFR Inhibition Potentiates FGFR Inhibitor Therapy and Overcomes Resistance in FGFR2 Fusion-Positive Cholangiocarcinoma.
ヒト・動物細胞 Ba/F3 Structural Optimization of Fibroblast Growth Factor Receptor Inhibitors for Treating Solid Tumors.
ヒト・動物細胞 NUGC-4(RCB1939) , MKN7(RCB0999) , MKN45(RCB1001) ARID1A deficiency is targetable by AKT inhibitors in HER2-negative gastric cancer.
ヒト・動物細胞 Ba/F3-CL1(RCB4474) Secondary Mutations of the EGFR Gene That Confer Resistance to Mobocertinib in EGFR Exon 20 Insertion.
ヒト・動物細胞 Li-7(RCB1941) WNTinib is a multi-kinase inhibitor with specificity against β-catenin mutant hepatocellular carcinoma.