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  • 15 Hits
  • Search Condition : Filter (MeSH = Protein Kinase Inhibitors / therapeutic use)
Species Resource
Human and Animal Cells Ba/F3(RCB0805) Dual blockade of EGFR tyrosine kinase using osimertinib and afatinib eradicates EGFR‑mutant Ba/F3 cells.
Human and Animal Cells CW-2(RCB0778) Pan-Cancer Landscape and Analysis of ERBB2 Mutations Identifies Poziotinib as a Clinically Active Inhibitor and Enhancer of T-DM1 Activity.
Human and Animal Cells StromaNKtert(RCB2350) Bruton's tyrosine kinase inhibition increases BCL-2 dependence and enhances sensitivity to venetoclax in chronic lymphocytic leukemia.
Human and Animal Cells 293T(RCB2202) Combined effect of cabozantinib and gefitinib in crizotinib-resistant lung tumors harboring ROS1 fusions.
Human and Animal Cells PC-9(RCB4455) AXL confers intrinsic resistance to osimertinib and advances the emergence of tolerant cells.
Human and Animal Cells TKKK(RCB1907) , TGBC24TKB(RCB1196) , HuCCT1(RCB1960) PI3K-mTOR pathway identified as a potential therapeutic target in biliary tract cancer using a newly established patient-derived cell panel assay.
Human and Animal Cells MH7A(RCB1512) Kinase inhibitors of the IGF-1R as a potential therapeutic agent for rheumatoid arthritis.
Human and Animal Cells LC-2/ad(RCB0440) EGF Induced RET Inhibitor Resistance in CCDC6-RET Lung Cancer Cells.
DNA material pFLAG-FIP1L1-PDGFRA-FL (RDB15460) , pFLAG-FIP1L1-PDGFRA-KD (RDB15461) , pFLAG-PDGFRA-C (RDB15462) , pCGT-FIP1L1-PDGFRA-FL (RDB15463) , pCGT-FIP1L1-PDGFRA-KD (RDB15464) , pCGT-PDGFRAC (RDB15465). Leukemogenic kinase FIP1L1-PDGFRA and a small ubiquitin-like modifier E3 ligase, PIAS1, form a positive cross-talk through their enzymatic activities.
DNA material pENTR4-H1 (RDB04395) , CS-RfA-EG (RDB04391) , CSII-CMV-RfA-IRES2-Venus (RDB04388) , pCMV-VSV-G-RSV-Rev (RDB04393) , pCAG-HIVgp (RDB04394). CD200-positive cancer associated fibroblasts augment the sensitivity of Epidermal Growth Factor Receptor mutation-positive lung adenocarcinomas to EGFR Tyrosine kinase inhibitors.
Human and Animal Cells Antitumor activity and induction of TP53-dependent apoptosis toward ovarian clear cell adenocarcinoma by the dual PI3K/mTOR inhibitor DS-7423.
Human and Animal Cells Effect of metformin on residual cells after chemotherapy in a human lung adenocarcinoma cell line.
Human and Animal Cells Novel HSP90 inhibitor NVP-AUY922 enhances the anti-tumor effect of temsirolimus against oral squamous cell carcinoma.
Human and Animal Cells Novel HER2 selective tyrosine kinase inhibitor, TAK-165, inhibits bladder, kidney and androgen-independent prostate cancer in vitro and in vivo.
Human and Animal Cells HER kinase activation confers resistance to MET tyrosine kinase inhibition in MET oncogene-addicted gastric cancer cells.