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  • 検索条件 : 絞込み (MeSH = Proto-Oncogene Proteins c-bcl-2 / metabolism*)
生物種 リソース名 タイトル
ヒト・動物細胞 Hep G2 , HeLa(RCB0007) Hepatitis C virus core protein inhibits apoptosis via enhanced Bcl-xL expression.
ヒト・動物細胞 TE-1(RCB1894) , TE-4(RCB2097) , TE-5(RCB1949) , TE-8(RCB2098) , TE-9(RCB1988) , TE-10(RCB2099) , TE-11(RCB2100) , TE-14(RCB2101) APR-246 induces apoptosis and enhances chemo-sensitivity via activation of ROS and TAp73-Noxa signal in oesophageal squamous cell cancer with TP53 missense mutation.
ヒト・動物細胞 COS-7(RCB0539) Bcl-2 and IP3 compete for the ligand-binding domain of IP3Rs modulating Ca2+ signaling output.
ヒト・動物細胞 TE-1(RCB1894) , TE-4(RCB2097) , TE-5(RCB1949) , TE-6(RCB1950) , TE-8(RCB2098) , TE-9(RCB1988) , TE-10(RCB2099) , TE-11(RCB2100) , TE-14(RCB2101) PRIMA-1 induces p53-mediated apoptosis by upregulating Noxa in esophageal squamous cell carcinoma with TP53 missense mutation.
ヒト・動物細胞 CACO-2(RCB0988) , COLO205(RCB2127) Rebamipide suppresses 5-fluorouracil-induced cell death via the activation of Akt/mTOR pathway and regulates the expression of Bcl-2 family proteins.
ヒト・動物細胞 StromaNKtert(RCB2350) hBfl-1/hNOXA Interaction Studies Provide New Insights on the Role of Bfl-1 in Cancer Cell Resistance and for the Design of Novel Anticancer Agents.
線虫 tm4559 , tm690 , tm4171 Hepatitis B virus X protein targets the Bcl-2 protein CED-9 to induce intracellular Ca2+ increase and cell death in Caenorhabditis elegans.
線虫 tm1108 A molecular switch that governs mitochondrial fusion and fission mediated by the BCL2-like protein CED-9 of Caenorhabditis elegans.
ヒト・動物細胞 SK-N-SH(RCB0426) , NB9(RCB0477) , NB19(RCB0479) , NB69(RCB0480) Stress via p53 pathway causes apoptosis by mitochondrial Noxa upregulation in doxorubicin-treated neuroblastoma cells.
ヒト・動物細胞 WI-38 Senescent cells are resistant to death despite low Bcl-2 level.
ヒト・動物細胞 Survivin, bcl-2 and matrix metalloproteinase-2 enhance progression of clear cell- and serous-type ovarian carcinomas.
ヒト・動物細胞 Differential responses of Bcl-2 family genes to etoposide in chronic myeloid leukemia K562 cells.
ヒト・動物細胞 PC-12(RCB0009) Hyperoxia induces the neuronal differentiated phenotype of PC12 cells via a sustained activity of mitogen-activated protein kinase induced by Bcl-2.
ヒト・動物細胞 HeLa(RCB0007) Changes in nuclear morphology during apoptosis correlate with vimentin cleavage by different caspases located either upstream or downstream of Bcl-2 action.
ヒト・動物細胞 IEC 6(RCB0993) Nitric oxide regulates energy metabolism and Bcl-2 expression in intestinal epithelial cells.
ヒト・動物細胞 StromaNKtert(RCB2350) , KUSA-H1(RCB1990) Homoharringtonine reduced Mcl-1 expression and induced apoptosis in chronic lymphocytic leukemia.
ショウジョウバエ 12284R-2 The pro-apoptotic activity of Drosophila Rbf1 involves dE2F2-dependent downregulation of diap1 and buffy mRNA.
実験動物マウス RBRC00806 Mst1 inhibits autophagy by promoting the interaction between Beclin1 and Bcl-2.
ヒト・動物細胞 T98G(RCB1954) MEK-ERK-dependent multiple caspase activation by mitochondrial proapoptotic Bcl-2 family proteins is essential for heavy ion irradiation-induced glioma cell death.
ヒト・動物細胞 PC-12(RCB0009) , SK-N-SH(RCB0426) Sunitinib induces apoptosis in pheochromocytoma tumor cells by inhibiting VEGFR2/Akt/mTOR/S6K1 pathways through modulation of Bcl-2 and BAD.