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  • Search Condition : Filter (MeSH = Proto-Oncogene Proteins c-mdm2 / genetics)
Species Resource Title
Human and Animal Cells HCT116(RCB2979) , COLO205(RCB2127) SHARPIN is a novel gene of colorectal cancer that promotes tumor growth potentially via inhibition of p53 expression.
Human and Animal Cells A172(RCB2530) , T98G(RCB1954) CEP-1347 Targets MDM4 Protein Expression to Activate p53 and Inhibit the Growth of Glioma Cells.
Human and Animal Cells CHP-134(RCB0487) , NB9(RCB0477) , NB69(RCB0480) Loss of DNA Damage Response in Neuroblastoma and Utility of a PARP Inhibitor.
Human and Animal Cells Lu99(RCB1900) Selective inhibition of histone deacetylase 2 induces p53-dependent survivin downregulation through MDM2 proteasomal degradation.
Human and Animal Cells JHOC-7(RCB1688) , JHOC-9(RCB2226) MDM2 is a potential therapeutic target and prognostic factor for ovarian clear cell carcinomas with wild type TP53.
DNA material CSII-CMV-MCS-IRES2-Bsd (RDB04385) , pCMV-VSV-G-RSV-Rev (RDB04393) , pCAG-HIVgp (RDB04394) Acute HSF1 depletion induces cellular senescence through the MDM2-p53-p21 pathway in human diploid fibroblasts.
Human and Animal Cells 293T(RCB2202) Synergistic cooperation of MDM2 and E2F1 contributes to TAp73 transcriptional activity.
Human and Animal Cells ST2(RCB0224) Soy protein isolate down-regulates caveolin-1 expression to suppress osteoblastic cell senescence pathways.
Human and Animal Cells DDX31 regulates the p53-HDM2 pathway and rRNA gene transcription through its interaction with NPM1 in renal cell carcinomas.
Human and Animal Cells Hep G2 Expression of CAR in SW480 and HepG2 cells during G1 is associated with cell proliferation.
Human and Animal Cells Hepatitis C virus impairs p53 via persistent overexpression of 3beta-hydroxysterol Delta24-reductase.
Human and Animal Cells MKN45(RCB1001) , NUGC-4(RCB1939) , WERI-Rb-1(RCB2146) Potent in vitro and in vivo antitumor effects of MDM2 inhibitor nutlin-3 in gastric cancer cells.