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論文 - 一覧

  • 11 Hits
  • 検索条件 : 絞込み (MeSH = Proto-Oncogene Proteins p21(ras)* / genetics)
生物種 リソース名 タイトル
ヒト・動物細胞 KP4(RCB1005) Combination of the MTA-Cooperative PRMT5 Inhibitor BMS-986504 and KRAS Inhibitors Is an Effective Treatment Strategy for MTAP-Deleted KRAS-Mutant Pancreatic Cancer.
ヒト・動物細胞 CW-2(RCB0778) Co-targeting KRASG12D and the HER family is efficacious in colorectal cancer.
ヒト・動物細胞 HSKTC(RCB0515) , HuG1-N(RCB1179) , KE-39(RCB1434) Pan-KRAS Inhibitors BI-2493 and BI-2865 Display Potent Antitumor Activity in Tumors with KRAS Wild-type Allele Amplification.
遺伝子材料 pTcf7wtluc (RDB02968) Basroparib overcomes acquired resistance to MEK inhibitors by inhibiting Wnt-mediated cancer stemness in KRAS-mutated colorectal cancer.
ヒト・動物細胞 GSU(RCB2278) , TGBC11TKB(RCB1148) Targeting KRAS-mutant stomach/colorectal tumors by disrupting the ERK2-p53 complex.
ヒト・動物細胞 TT1TKB(RCB1185) Targeting ALDH1A1 to enhance the efficacy of KRAS-targeted therapy through ferroptosis.
遺伝子材料 CSII-CMV-MCS-IRES2-Bsd (RDB04385) , pCMV-VSV-G-RSV-Rev (RDB04393) , pCAG-HIVgp (RDB04394) An ATR-PrimPol pathway confers tolerance to oncogenic KRAS-induced and heterochromatin-associated replication stress.
ヒト・動物細胞 NIH3T3 MEK inhibitors and DA-Raf, a dominant-negative antagonist of the Ras-ERK pathway, prevent the migration and invasion of KRAS-mutant cancer cells.
ヒト・動物細胞 Lu99(RCB1900) The SOS1 Inhibitor MRTX0902 Blocks KRAS Activation and Demonstrates Antitumor Activity in Cancers Dependent on KRAS Nucleotide Loading.
ヒト・動物細胞 KP4(RCB1005) , KP4-1(RCB1006) , PK-59(RCB1901) Snail acetylation by autophagy-derived acetyl-coenzyme A promotes invasion and metastasis of KRAS-LKB1 co-mutated lung cancer cells.
ヒト・動物細胞 HuCCT1(RCB1960) , RBE(RCB1292) KRAS mutation in intrahepatic cholangiocarcinoma: Linkage with metastasis-free survival and reduced E-cadherin expression.