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  • 検索条件 : 絞込み (MeSH = Proto-Oncogene Proteins p21(ras) / antagonists & inhibitors*)
生物種 リソース名 RRC ID タイトル ジャーナル 公開日 外部リンク
ヒト・動物細胞 Ba/F3(RCB0805) 69464 Clinical Acquired Resistance to KRASG12C Inhibition through a Novel KRAS Switch-II Pocket Mutation and Polyclonal Alterations Converging on RAS-MAPK Reactivation. Cancer Discov 2021-8-1 Pubmed Full text
ヒト・動物細胞 LU99(RCB1900) , LU65(RCB1967) , IA-LM(RCB0554) 68965 The KRASG12C Inhibitor MRTX849 Provides Insight toward Therapeutic Susceptibility of KRAS-Mutant Cancers in Mouse Models and Patients. Cancer Discov 2020-1-1 Pubmed Full text
ヒト・動物細胞 PC-9(RCB4455) 65151 Activation of KRAS Mediates Resistance to Targeted Therapy in MET Exon 14-mutant Non-small Cell Lung Cancer. Clin Cancer Res 2019-2-15 Pubmed Full text
ヒト・動物細胞 HL60(RCB0041) , U-937 DE-4(RCB0435) 61871 Nitrogen-containing bisphosphonates induce apoptosis of hematopoietic tumor cells via inhibition of Ras signaling pathways and Bim-mediated activation of the intrinsic apoptotic pathway. Biochem Pharmacol 2013-1-15 Pubmed Full text
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