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Human and Animal Cells MKN45(RCB1001) , MKN74(RCB1002) A preserved TGFβ cytostatic response through DLD-mediated metabolic modulation undermines anti-TGFβ therapy in gastric cancer.
Human and Animal Cells K562(RCB0027) Asciminib, a novel allosteric inhibitor of BCR-ABL1, shows synergistic effects when used in combination with imatinib with or without drug resistance.
Human and Animal Cells Ba/F3(RCB0805) Molecular Mechanisms of Resistance to First- and Second-Generation ALK Inhibitors in ALK-Rearranged Lung Cancer.
Human and Animal Cells Ba/F3 NVL-520 Is a Selective, TRK-Sparing, and Brain-Penetrant Inhibitor of ROS1 Fusions and Secondary Resistance Mutations.
Human and Animal Cells Ba/F3(RCB0805) Analysis of lorlatinib analogs reveals a roadmap for targeting diverse compound resistance mutations in ALK-positive lung cancer.
Human and Animal Cells Ba/F3 Sequential ALK Inhibitors Can Select for Lorlatinib-Resistant Compound ALK Mutations in ALK-Positive Lung Cancer.
Clawed frogs / Newts Acute and chronic toxicity tests of systemic insecticides, four neonicotinoids and fipronil, using the tadpoles of the western clawed frog Silurana tropicalis.
Human and Animal Cells ATDC5(RCB0565) Prostacyclin regulates bone growth via the Epac/Rap1 pathway.
Human and Animal Cells Colon-26(RCB2657) Ibudilast suppresses oxaliplatin-induced mechanical allodynia and neurodegeneration in rats.
Human and Animal Cells Ba/F3 The new-generation selective ROS1/NTRK inhibitor DS-6051b overcomes crizotinib resistant ROS1-G2032R mutation in preclinical models.