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  • 14 Hits
  • 検索条件 : 絞込み (MeSH = Pyrimidines)
生物種 リソース名 タイトル
実験動物マウス RBRC01361 JAK2V617F+ myeloproliferative neoplasm clones evoke paracrine DNA damage to adjacent normal cells through secretion of lipocalin-2.
ヒト・動物細胞 Ba/F3 Targeting EGFR-Mcl-1 Axis by Piperlongumine as a Novel Strategy for Non-Small Cell Lung Cancer Therapy.
ヒト・動物細胞 Ba/F3(RCB4476) Efficacy of Conventional and Novel Tyrosine Kinase Inhibitors for Uncommon EGFR Mutations-An In Vitro Study.
ヒト・動物細胞 PC-9(RCB4455) MicroRNA-130a-3p regulates osimertinib resistance by targeting runt-related transcription factor 3 in lung adenocarcinoma.
遺伝子材料 tFucci(CA)2/pCSII-EF (RDB15446) A bispecific antibody targeting EGFR and AXL delays resistance to osimertinib.
ヒト・動物細胞 Lu99(RCB1900) The SOS1 Inhibitor MRTX0902 Blocks KRAS Activation and Demonstrates Antitumor Activity in Cancers Dependent on KRAS Nucleotide Loading.
ヒト・動物細胞 Lu99(RCB1900) , LU65(RCB1967) Activity of Adagrasib (MRTX849) in Brain Metastases: Preclinical Models and Clinical Data from Patients with KRASG12C-Mutant Non-Small Cell Lung Cancer.
ヒト・動物細胞 Ba/F3(RCB0805) , WEHI-3(RCB0035) Foretinib can overcome common on-target resistance mutations after capmatinib/tepotinib treatment in NSCLCs with MET exon 14 skipping mutation.
ヒト・動物細胞 Ba/F3(RCB0805) KRAS Secondary Mutations That Confer Acquired Resistance to KRAS G12C Inhibitors, Sotorasib and Adagrasib, and Overcoming Strategies: Insights From In Vitro Experiments.
ヒト・動物細胞 LU99(RCB1900) , LU65(RCB1967) , IA-LM(RCB0554) The KRASG12C Inhibitor MRTX849 Provides Insight toward Therapeutic Susceptibility of KRAS-Mutant Cancers in Mouse Models and Patients.
ヒト・動物細胞 EBC-1(RCB1965) Drug resistance via feedback activation of Stat3 in oncogene-addicted cancer cells.
ヒト・動物細胞 COLO205(RCB2127) AAG8 promotes carcinogenesis by activating STAT3.
ヒト・動物細胞 Ba/F3(RCB0805) Resveratrol selectively induces apoptosis in malignant cells with the JAK2V617F mutation by inhibiting the JAK2 pathway.
実験動物マウス RBRC02290 Tracing the conversion process from primordial germ cells to pluripotent stem cells in mice.