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Species Resource Title
DNA material tFucci(CA)2/pCSII-EF (RDB15446) A bispecific antibody targeting EGFR and AXL delays resistance to osimertinib.
Human and Animal Cells Lu99(RCB1900) , LU65(RCB1967) Activity of Adagrasib (MRTX849) in Brain Metastases: Preclinical Models and Clinical Data from Patients with KRASG12C-Mutant Non-Small Cell Lung Cancer.
Human and Animal Cells Ba/F3(RCB0805) , WEHI-3(RCB0035) Foretinib can overcome common on-target resistance mutations after capmatinib/tepotinib treatment in NSCLCs with MET exon 14 skipping mutation.
Human and Animal Cells Ba/F3(RCB0805) KRAS Secondary Mutations That Confer Acquired Resistance to KRAS G12C Inhibitors, Sotorasib and Adagrasib, and Overcoming Strategies: Insights From In Vitro Experiments.
Human and Animal Cells LU99(RCB1900) , LU65(RCB1967) , IA-LM(RCB0554) The KRASG12C Inhibitor MRTX849 Provides Insight toward Therapeutic Susceptibility of KRAS-Mutant Cancers in Mouse Models and Patients.
Human and Animal Cells EBC-1(RCB1965) Drug resistance via feedback activation of Stat3 in oncogene-addicted cancer cells.
Human and Animal Cells COLO205(RCB2127) AAG8 promotes carcinogenesis by activating STAT3.
Human and Animal Cells Ba/F3(RCB0805) Resveratrol selectively induces apoptosis in malignant cells with the JAK2V617F mutation by inhibiting the JAK2 pathway.
Mice RBRC02290 Tracing the conversion process from primordial germ cells to pluripotent stem cells in mice.