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Species Resource Title
Rats ラット系統樹 , Based on the analyses for genetic polymorphisms, the three rat substrains used here had identical genetic backgrounds (personal communication with Prof. Ota, Department of Pathology, Kindai University Nara Hospital; National Bioresource Project ‘Rat’ in Kyoto University (http://www.anim.med.kyoto-u.ac.jp/nbr/phylo_jp.aspx#SHR)). Hypertension-Associated Genes in the Mesenteric Artery of Three Spontaneously Hypertensive Rat Substrains Identified Using a DNA Array Method.
Human and Animal Cells MDCK(RCB0995) Pioglitazone lowers systemic asymmetric dimethylarginine by inducing dimethylarginine dimethylaminohydrolase in rats.
Human and Animal Cells U-937 DE-4(RCB0435) Vasculo-protective effect of BMS-309403 is independent of its specific inhibition of fatty acid-binding protein 4.
Rats In order to test if other genetically-inbred hypertensive rat strains also exhibit diminished serum cholesterol levels with respect to their controls, we retrieved serum total cholesterol and systolic blood pressure values of 21 strains from the National BioResource Project- Rat (http://www.anim.med.kyoto-u.ac.jp/nbr/) and PhenoMiner tool of the Rat Genome Database (RGD; http://rgd.mcw.edu/rgdweb/search/qtls.html?100) (Table S3). An evolutionarily-conserved promoter allele governs HMG-CoA reductase expression in spontaneously hypertensive rat.
Human and Animal Cells LLC-GA5-CoL150(RCB0871) Role of P-glycoprotein in regulating cilnidipine distribution to intact and ischemic brain.
Rats W-Tg(CAG-GFP)184Ys (strainID=525) Intravenous infusion of mesenchymal stem cells improves impaired cognitive function in a cerebral small vessel disease model.
Rats DON/Kyo (strainID=1) Further dissection of QTLs for salt-induced stroke and identification of candidate genes in the stroke-prone spontaneously hypertensive rat.
Human and Animal Cells Ctip2-mediated Sp6 transcriptional regulation in dental epithelium-derived cells.
Human and Animal Cells U937 Eukaryotic elongation factor 2 kinase regulates the development of hypertension through oxidative stress-dependent vascular inflammation.
Human and Animal Cells U937 HDAC4 mediates development of hypertension via vascular inflammation in spontaneous hypertensive rats.
DNA material AxCAmTSC-22 (forward) (RDB02760) , AxCALacZ (RDB01745) TSC-22 up-regulates collagen 3a1 gene expression in the rat heart.
Rats DNA samples(W/KYO(strainID=13) , WKYO/Kyo(strainID=17) , SDJ/Hok(strainID=74) , LEJ/Hok(strainID=72) , SS/JrNgs(strainID=798) , SR/JrNgs(strainID=799) ) Identification of Stim1 as a candidate gene for exaggerated sympathetic response to stress in the stroke-prone spontaneously hypertensive rat.
Rats WKY/Izm(strainID=412) , SHRSP/Izm(strainID=409) , SHR.SHRSP-(D1Rat93-D1Rat269)(D18Rat73-D18Rat11)/Izm(strainID=1082) Arginine vasopressin regulated ASCT1 expression in astrocytes from stroke-prone spontaneously hypertensive rats and congenic SHRpch1_18 rats.
Rats SHRSP/5Dmcr(strainID=737) Simultaneous changes in high-fat and high-cholesterol diet-induced steatohepatitis and severe fibrosis and those underlying molecular mechanisms in novel SHRSP5/Dmcr rat.
Rats SHR/Izm(strainID=411) , SHRSP/Izm(strainID=409) Standards and pitfalls of focal ischemia models in spontaneously hypertensive rats: with a systematic review of recent articles.
Rats SHRSP/Ezo(strainID=357) Behavioural effects of monoamine reuptake inhibitors on symptomatic domains in an animal model of attention-deficit/hyperactivity disorder.
Rats SHR/NCrlCrlj(strainID=478) Two genomic regions of chromosomes 1 and 18 explain most of the stroke susceptibility under salt loading in stroke-prone spontaneously hypertensive rat/Izm.
DNA material pco12 EGFR Human EGF receptor cDNA (RDB01276) Enhanced expression of heparin-binding EGF-like growth factor and its receptor in hypertrophied left ventricle of spontaneously hypertensive rats.
DNA material pBS rcjun-1 (RDB01130) Heat shock protein expression in hearts hypertrophied by genetic and nongenetic hypertension.
DNA material pTGF-11 (RDB01195) Dietary docosahexaenoic acid ameliorates, but rapeseed oil and safflower oil accelerate renal injury in stroke-prone spontaneously hypertensive rats as compared with soybean oil, which is associated with expression for renal transforming growth factor-beta, fibronectin and renin.