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  • Search Condition : Filter (MeSH = Toll-Like Receptor 4 / metabolism*)
Species Resource Title
Human and Animal Cells Hep G2(RCB1886) Sulforaphane ameliorates ethanol plus carbon tetrachloride-induced liver fibrosis in mice through the Nrf2-mediated antioxidant response and acetaldehyde metabolization with inhibition of the LPS/TLR4 signaling pathway.
Human and Animal Cells 293(RCB1637) Direct binding of TRAF2 and TRAF6 to TICAM-1/TRIF adaptor participates in activation of the Toll-like receptor 3/4 pathway.
Human and Animal Cells RAW 264(RCB0535) Lipopolysaccharide decreases single immunoglobulin interleukin-1 receptor-related molecule (SIGIRR) expression by suppressing specificity protein 1 (Sp1) via the Toll-like receptor 4 (TLR4)-p38 pathway in monocytes and neutrophils.
Human and Animal Cells RAW 264(RCB0535) β-(1→4)-Mannobiose Acts as an Immunostimulatory Molecule in Murine Dendritic Cells by Binding the TLR4/MD-2 Complex.
Human and Animal Cells THP-1(RCB1189) Involvement of reactive oxygen species in ionizing radiation-induced upregulation of cell surface Toll-like receptor 2 and 4 expression in human monocytic cells.
Mice RBRC06240 Extracellular HMGB1 augments macrophage inflammation by facilitating the endosomal accumulation of ALD-DNA via TLR2/4-mediated endocytosis.
Human and Animal Cells 293T(RCB2202) Clostridioides difficile toxins enhanced the in vitro production of CXC chemokine ligand 2 and tumor necrosis factor-α via Toll-like receptors in macrophages.
Human and Animal Cells 293T(RCB2202) Homeostatic and pathogenic roles of GM3 ganglioside molecular species in TLR4 signaling in obesity.
Human and Animal Cells J774 Syntaxin 11 regulates the stimulus-dependent transport of Toll-like receptor 4 to the plasma membrane by cooperating with SNAP-23 in macrophages.
Human and Animal Cells MG6(RCB2403) CD14 and Toll-Like Receptor 4 Promote Fibrillar Aβ42 Uptake by Microglia Through A Clathrin-Mediated Pathway.
Mice RBRC02388 Selective targeting of the TLR4 co-receptor, MD2, prevents colon cancer growth and lung metastasis.
Human and Animal Cells HuH-7 TLR4-mediated pyroptosis in human hepatoma-derived HuH-7 cells induced by a branched-chain polyunsaturated fatty acid, geranylgeranoic acid.
Human and Animal Cells LM8(RCB1450) Activation of TLR4 signaling inhibits progression of osteosarcoma by stimulating CD8-positive cytotoxic lymphocytes.
Human and Animal Cells RAW 264(RCB0535) Enhanced Cellular Polysulfides Negatively Regulate TLR4 Signaling and Mitigate Lethal Endotoxin Shock.
Human and Animal Cells RAW 264(RCB0535) Inhibitory Effect of Carotenoids on Ligand-induced Lipid Raft Translocation of Immunoreceptors.
Human and Animal Cells RAW 264(RCB0535) , 293(RCB1637) Lipopolysaccharide (LPS)-binding protein stimulates CD14-dependent Toll-like receptor 4 internalization and LPS-induced TBK1-IKKϵ-IRF3 axis activation.
Human and Animal Cells 293(RCB1637) Plasmalogens Inhibit Endocytosis of Toll-like Receptor 4 to Attenuate the Inflammatory Signal in Microglial Cells.
Human and Animal Cells RAW 264(RCB0535) , ST2(RCB0224) , 293(RCB1637) γ-Glutamyltranspeptidase is an endogenous activator of Toll-like receptor 4-mediated osteoclastogenesis.
Human and Animal Cells J774.1(RCB0434) The H3K9 methyltransferase Setdb1 regulates TLR4-mediated inflammatory responses in macrophages.
Human and Animal Cells ATDC5(RCB0565) The novel adipokine progranulin counteracts IL-1 and TLR4-driven inflammatory response in human and murine chondrocytes via TNFR1.