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  • Search Condition : Filter (MeSH = Ubiquitin-Protein Ligases / metabolism)
Species Resource Title
Drosophila pVHL-mediated SMAD3 degradation suppresses TGF-β signaling.
Drosophila DGRC#110685 Par3 cooperates with Sanpodo for the assembly of Notch clusters following asymmetric division of Drosophila sensory organ precursor cells.
Human and Animal Cells WERI-Rb-1(RCB2146) Protein Profiling of WERI-RB1 and Etoposide-Resistant WERI-ETOR Reveals New Insights into Topoisomerase Inhibitor Resistance in Retinoblastoma.
Human and Animal Cells P19.CL6(RCB2318) ASB2 is a novel E3 ligase of SMAD9 required for cardiogenesis.
Human and Animal Cells C2C12(RCB0987) Eicosapentaenoic acid suppresses cisplatin-induced muscle atrophy by attenuating the up-regulated gene expression of ubiquitin.
Human and Animal Cells WI-38(RCB0702) , HeLa ATM and SIRT6/SNF2H Mediate Transient H2AX Stabilization When DSBs Form by Blocking HUWE1 to Allow Efficient γH2AX Foci Formation.
Human and Animal Cells HuCCT1(RCB1960) FBXW7 suppresses epithelial-mesenchymal transition, stemness and metastatic potential of cholangiocarcinoma cells.
Human and Animal Cells DT40(RCB1464) Targeted siRNA Screens Identify ER-to-Mitochondrial Calcium Exchange in Autophagy and Mitophagy Responses in RPE1 Cells.
Human and Animal Cells MCF7(RCB1904) , 293T(RCB2202) SCF(Fbxo22)-KDM4A targets methylated p53 for degradation and regulates senescence.
Human and Animal Cells HepG2 Causative role for defective expression of mitochondria-eating protein in accumulation of mitochondria in thyroid oncocytic cell tumors.
Human and Animal Cells HeLa , 293(RCB1637) Mitochondrial ubiquitin ligase activator of NF-κB regulates NF-κB signaling in cells subjected to ER stress.
Human and Animal Cells OS-RC-2(RCB0735) The Arkadia-ESRP2 axis suppresses tumor progression: analyses in clear-cell renal cell carcinoma.
Human and Animal Cells 293T(RCB2202) Activation of c-Jun by human cytomegalovirus UL42 through JNK activation.
Human and Animal Cells Atg5^(+/+)MEF(RCB2710) , Atg5^(-/-)MEF(RCB2711) p62/SQSTM1/Sequestosome-1 is an N-recognin of the N-end rule pathway which modulates autophagosome biogenesis.
C.elegans tm4525 , tm4919 Mitochondrial UPR repression during Pseudomonas aeruginosa infection requires the bZIP protein ZIP-3.
Mice RBRC02759 Impaired mitophagy links mitochondrial disease to epithelial stress in methylmalonyl-CoA mutase deficiency.
Mice RBRC05494 Targeting Degradation of the Transcription Factor C/EBPβ Reduces Lung Fibrosis by Restoring Activity of the Ubiquitin-Editing Enzyme A20 in Macrophages.
Drosophila Insight into Notch Signaling Steps That Involve pecanex from Dominant-Modifier Screens in Drosophila.
DNA material pFLAG-CMV-5a-RPL23 (RDB17324) , pGEX6P-1-RPL23 (RDB17325) , pET-28a-RPL23 (RDB17326) , pCLH'CX-His-T7-RPL23 (RDB17327) , pCMV-GRWD1 (RDB17328) GRWD1 regulates ribosomal protein L23 levels via the ubiquitin-proteasome system.
DNA material pMK344 (Hygro-P2A-mAID) (RDB16805) , pMK345 (Hygro-P2A-mAID-mClover) (RDB16806) , pMK346 (Hygro-P2A-mAID-mCherry) (RDB16807) , pMK347 (BSD-P2A-mAID) (RDB16808) , pMK348 (BSD-P2A-mAID-mClover) (RDB16809) , pMK349 (BSD-P2A-mAID-mCherry) (RDB16810) , pMK364 (CMV-OsTIR1-loxP-PURO-loxP) (RDB16811) , pMK375 (Hygro-P2A-Stag-3FLAG) (RDB16813) , pMK376 (Hygro-P2A-mClover) (RDB16814) , pMK377 (Hygro-P2A-mCherry2) (RDB16815) , ... Generation of conditional auxin-inducible degron (AID) cells and tight control of degron-fused proteins using the degradation inhibitor auxinole.