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  • Search Condition : Filter (MeSH = Ubiquitin-Protein Ligases / metabolism)
Species Resource Title
Drosophila 3016R-2 FBXO7/ntc and USP30 antagonistically set the ubiquitination threshold for basal mitophagy and provide a target for Pink1 phosphorylation in vivo.
C.elegans tm1380 A heterotypic assembly mechanism regulates CHIP E3 ligase activity.
C.elegans tm1779 Mitochondria-affecting small molecules ameliorate proteostasis defects associated with neurodegenerative diseases.
Human and Animal Cells 293T(RCB2202) FBXO11 constitutes a major negative regulator of MHC class II through ubiquitin-dependent proteasomal degradation of CIITA.
Drosophila DGRC#109029 , HMS01352 , HMJ30245 , 5862R-1 A neuroprotective role of Ufmylation through Atg9 in the aging brain of Drosophila.
Lotus / Glycine Gifu B-129, MG-20 RPG interacts with E3-ligase CERBERUS to mediate rhizobial infection in Lotus japonicus
Yeast FY18665 Environmental control of Pub1 (NEDD4 family E3 ligase) in Schizosaccharomyces pombe is regulated by TORC2 and Gsk3.
DNA material CSII-CMV-MCS-IRES2-Bsd (RDB04385) , pCMV-VSV-G-RSV-Rev (RDB04393) , pCAG-HIVgp (RDB04394) A distinct mammalian disome collision interface harbors K63-linked polyubiquitination of uS10 to trigger hRQT-mediated subunit dissociation.
Human and Animal Cells HeLa/Fucci(RCB2812) The Ubiquitin Ligase RNF138 Cooperates with CtIP to Stimulate Resection of Complex DNA Double-Strand Breaks in Human G1-Phase Cells.
Human and Animal Cells PANC-1(RCB2095) PINK1-dependent and Parkin-independent mitophagy is involved in reprogramming of glycometabolism in pancreatic cancer cells.
Drosophila pVHL-mediated SMAD3 degradation suppresses TGF-β signaling.
Drosophila DGRC#110685 Par3 cooperates with Sanpodo for the assembly of Notch clusters following asymmetric division of Drosophila sensory organ precursor cells.
Human and Animal Cells WERI-Rb-1(RCB2146) Protein Profiling of WERI-RB1 and Etoposide-Resistant WERI-ETOR Reveals New Insights into Topoisomerase Inhibitor Resistance in Retinoblastoma.
Human and Animal Cells 293(RCB1637) , HeLa(RCB0007) Ubiquitination at the lysine 27 residue of the Parkin ubiquitin-like domain is suggestive of a new mechanism of Parkin activation.
Human and Animal Cells P19.CL6(RCB2318) ASB2 is a novel E3 ligase of SMAD9 required for cardiogenesis.
Human and Animal Cells C2C12(RCB0987) Eicosapentaenoic acid suppresses cisplatin-induced muscle atrophy by attenuating the up-regulated gene expression of ubiquitin.
DNA material CS-RfA-ETBsd (RDB07917) , pCMV-VSV-G-RSV-Rev (RDB04393) , pCAG-HIVgp (RDB04394) Calcineurin regulates the stability and activity of estrogen receptor α.
Drosophila pBFvU6.2 , DGRC#104055 Hecw controls oogenesis and neuronal homeostasis by promoting the liquid state of ribonucleoprotein particles.
Human and Animal Cells WI-38(RCB0702) , HeLa ATM and SIRT6/SNF2H Mediate Transient H2AX Stabilization When DSBs Form by Blocking HUWE1 to Allow Efficient γH2AX Foci Formation.
Human and Animal Cells HuCCT1(RCB1960) FBXW7 suppresses epithelial-mesenchymal transition, stemness and metastatic potential of cholangiocarcinoma cells.