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  • 62 Hits
  • Search Condition : Filter (MeSH = Ubiquitin-Protein Ligases / metabolism)
Species Resource
Yeast BYP6744, BYP7425 Msp1 Clears Mistargeted Proteins by Facilitating Their Transfer from Mitochondria to the ER.
Drosophila Insight into Notch Signaling Steps That Involve pecanex from Dominant-Modifier Screens in Drosophila.
C.elegans tm1361 The E3 Ubiquitin Ligase MIB-1 Is Necessary To Form the Nuclear Halo in Caenorhabditis elegans Sperm.
C.elegans tm1746 MAPK signaling couples SCF-mediated degradation of translational regulators to oocyte meiotic progression.
C.elegans tm3543 RNAi-Based Suppressor Screens Reveal Genetic Interactions Between the CRL2LRR-1 E3-Ligase and the DNA Replication Machinery in Caenorhabditis elegans.
C.elegans tm4919 , tm1779 , tm598 Maintenance and propagation of a deleterious mitochondrial genome by the mitochondrial unfolded protein response.
Human and Animal Cells 293T(RCB2202) , JM(RCB0537) Herpesviruses possess conserved proteins for interaction with Nedd4 family ubiquitin E3 ligases.
Human and Animal Cells 201B7(HPS0063) Down-regulation of ghrelin receptors on dopaminergic neurons in the substantia nigra contributes to Parkinson's disease-like motor dysfunction.
Human and Animal Cells MCF7(RCB1904) The prolyl oligopeptidase inhibitor SUAM-14746 attenuates the proliferation of human breast cancer cell lines in vitro.
Human and Animal Cells TE-1(RCB1894) Targeted inhibition of the COP9 signalosome for treatment of cancer.
Human and Animal Cells MKN45(RCB1001) Neddylation inhibitor MLN4924 suppresses growth and migration of human gastric cancer cells.
C.elegans tm5447 Novel animal model defines genetic contributions for neuron-to-neuron transfer of α-synuclein.
C.elegans tm1683 , tm2312 Increased mitochondrial fusion allows the survival of older animals in diverse C. elegans longevity pathways.
C.elegans tm1108 , tm1133 , tm1779 Deficiencies in mitochondrial dynamics sensitize Caenorhabditis elegans to arsenite and other mitochondrial toxicants by reducing mitochondrial adaptability.
C.elegans tm5996 Coupled Caspase and N-End Rule Ligase Activities Allow Recognition and Degradation of Pluripotency Factor LIN-28 during Non-Apoptotic Development.
Drosophila 7425R-1 , 9924R-1 UbcD1 regulates Hedgehog signaling by directly modulating Ci ubiquitination and processing.
Human and Animal Cells , Drosophila HeLa , 293T(RCB2202) Loss of Parkinson's disease-associated protein CHCHD2 affects mitochondrial crista structure and destabilizes cytochrome c.
DNA material pHIS3K-Ptub1 (RDB06564) SUMO-Targeted DNA Translocase Rrp2 Protects the Genome from Top2-Induced DNA Damage.
Yeast FY20581 , FY7884 , cdc48 and top2 ts mutant S. pombe strains. SUMO-Targeted DNA Translocase Rrp2 Protects the Genome from Top2-Induced DNA Damage.
Drosophila 6190R-3 Drosophila Ube3a regulates monoamine synthesis by increasing GTP cyclohydrolase I activity via a non-ubiquitin ligase mechanism.