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  • Search Condition : Filter (MeSH = Ubiquitination)
Species Resource Title
C.elegans tm1133 , tm1968 Inactivation of SIAH-1 E3 ligase attenuates Aβ toxicity by suppressing ubiquitin-dependent DVE-1 degradation in Caenorhabditis elegans models of Alzheimer's disease.
DNA material pCAGGS (RDB08938) , pCMV-VSV-G-RSV-Rev (RDB04393) , pCAG-HIVgp (RDB04394) , CSII-CMV-MCS-IRES2-Bsd (RDB04385) An interactome-based framework for DDB1- and CUL4-associated factor prioritization in targeted protein degradation.
Arabidopsis / Cultured plant cells, genes pdi00103 CUL3LRB E3 ubiquitin ligases control thermosensory growth in Arabidopsis by differentially regulating HY5 and PIF4 protein stability.
Yeast FY23510 , FY23525 , FY23541 Histone H2B monoubiquitylation regulates elongation-to-termination transition in RNA polymerase II transcription.
Yeast PolySUMOylation of PCNA and Rad52 restricts centromeric recombination in fission yeast.
Human and Animal Cells HuH-7(RCB1366) , OS-RC-2(RCB0735) Deciphering the role of the MALT1-RC3H1 axis in regulating GPX4 protein stability.
Human and Animal Cells , DNA material 293T(RCB2202) , CSII-EF-MCS (RDB04378) , pCAG-HIVgp (RDB04394) , pCMV-VSV-G-RSV-Rev (RDB04393) ESCRT-I and PTPN23 mediate microautophagy of ubiquitylated tau aggregates.
Drosophila 6303R-1 , 6303R-2 , 2924R-3 , 4502R-2 , 7656R-2 , 7656R-1 , 8188R-1 , 8188R-2 , 7425R-2 , 7425R-1 , ... The ubiquitin-conjugating enzyme UBE2D maintains a youthful proteome and ensures protein quality control during aging by sustaining proteasome activity.
Human and Animal Cells HeLa(RCB0007) , HCT116(RCB2979) TanGIBLE: A selective probe for evaluating hydrophobicity-exposed defective proteins in live cells.
Human and Animal Cells , Mice MC3T3-E1(RCB1126) , RBRC05524 Phosphorylation-dependent osterix degradation negatively regulates osteoblast differentiation.
DNA material pCAG-HIVgp (RDB04394) , CS-RfA-CG (RDB04390) , pCMV-VSV-G-RSV-Rev (RDB04393) Long noncoding RNA UPAT promotes colon tumorigenesis by inhibiting degradation of UHRF1.
Mice RBRC00806 Identification of novel lipid droplet factors that regulate lipophagy and cholesterol efflux in macrophage foam cells.
Human and Animal Cells HeLa(RCB0007) Multi-tiered actions of Legionella effectors to modulate host Rab10 dynamics.
DNA material CS-RfA-ETBsd (RDB07917) , CSII-CMV-MCS (RDB04377) , pCMV-VSV-G-RSV-Rev (RDB04393) , pCAG-HIVgp (RDB04394) TP53/p53-FBXO22-TFEB controls basal autophagy to govern hormesis.
DNA material pCAG-HIVgp (RDB04394) , pCMV-VSV-G-RSV-Rev (RDB04393) Visualization of the cancer cell cycle by tissue-clearing technology using the Fucci reporter system.
DNA material pRSV-Rev (RDB08121) , pCMV-VSV-G (RDB04392) , pCAG-HIVgp (RDB04394) Ubiquitination of SARS-CoV-2 NSP6 and ORF7a Facilitates NF-κB Activation.
DNA material CSII-CMV-MCS-IRES2-Bsd (RDB04385) , pCMV-VSV-G-RSV-Rev (RDB04393) , pCAG-HIVgp (RDB04394) ENTREP/FAM189A2 encodes a new ITCH ubiquitin ligase activator that is downregulated in breast cancer.
DNA material CSII-CMV-MCS-IRES2-Bsd (RDB04385) , pCAG-HIVgp (RDB04394) , pCMV-VSV-G-RSV-Rev (RDB04393) Mechanistic insights into the roles of the UFM1 E3 ligase complex in ufmylation and ribosome-associated protein quality control.
Mice RBRC01828 The HOIL-1L ligase modulates immune signalling and cell death via monoubiquitination of LUBAC.
Mice RBRC09483 Systematic HOIP interactome profiling reveals critical roles of linear ubiquitination in tissue homeostasis.