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  • 検索条件 : 絞込み (MeSH = Zinc Finger Protein Gli2)
生物種 リソース名 タイトル
ヒト・動物細胞 RMS-YM(RCB1695) Pharmacological inhibition of the Hedgehog pathway prevents human rhabdomyosarcoma cell growth.
遺伝子材料 8x3'Gli-BS-delta51-LucII (RDB08061) Ciliary Entry of the Hedgehog Transcriptional Activator Gli2 Is Mediated by the Nuclear Import Machinery but Differs from Nuclear Transport in Being Imp-α/β1-Independent.
ヒト・動物細胞 HS-Os-1(RCB2229) Ribosomal protein S3 regulates GLI2-mediated osteosarcoma invasion.
ヒト・動物細胞 HS-Os-1(RCB2229) GLI2 is a novel therapeutic target for metastasis of osteosarcoma.
ヒト・動物細胞 Gli1 protein participates in Hedgehog-mediated specification of osteoblast lineage during endochondral ossification.
ヒト・動物細胞 10T1/2(RCB0247) , C2C12(RCB0987) , 293(RCB1637) , CHO-K1(RCB0285) Ihh/Gli2 signaling promotes osteoblast differentiation by regulating Runx2 expression and function.
ヒト・動物細胞 Identification of a suppressive mechanism for Hedgehog signaling through a novel interaction of Gli with 14-3-3.
ヒト・動物細胞 10T1/2(RCB0247) , COS-7(RCB0539) Sox9 family members negatively regulate maturation and calcification of chondrocytes through up-regulation of parathyroid hormone-related protein.
ヒト・動物細胞 COS-7(RCB0539) , 293(RCB1637) The transcription factor Foxc1 is necessary for Ihh-Gli2-regulated endochondral ossification.
ゼブラフィッシュ Tg(isl1:GFP)/rw0 The PCP protein Vangl2 regulates migration of hindbrain motor neurons by acting in floor plate cells, and independently of cilia function.
遺伝子材料 pcDNA3.1-His-hGLI1 (RDB08063) , pcDNA3.1-His-Gli1 (RDB08064) , pcDNA3.1-His-Gli2 (RDB08065) , pcDNA3.1-His-hGLI3 (RDB08066). Regulation of Gli2 and Gli3 activities by an amino-terminal repression domain: implication of Gli2 and Gli3 as primary mediators of Shh signaling.
遺伝子材料 8x3'Gli-BS-delta51-LucII (RDB08061) , 8xm3'Gli-BS-delta51-LucII (RDB08062) A binding site for Gli proteins is essential for HNF-3beta floor plate enhancer activity in transgenics and can respond to Shh in vitro.
ゼブラフィッシュ rw0(Tg(isl1:GFP)) Combined activity of the two Gli2 genes of zebrafish play a major role in Hedgehog signaling during zebrafish neurodevelopment.
ゼブラフィッシュ rw0 Gli function is essential for motor neuron induction in zebrafish.