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  • 検索条件 : 絞込み (MeSH = tau Proteins / metabolism*)
生物種 リソース名 タイトル
実験動物マウス RBRC02370 Spreading of Alzheimer tau seeds is enhanced by aging and template matching with limited impact of amyloid-β.
ヒト・動物細胞 Atg5^(+/+)MEF(RCB2710) , Atg5^(-/-)MEF(RCB2711) Tau phosphorylation affects its axonal transport and degradation.
ショウジョウバエ Disulfide bond formation in microtubule-associated tau protein promotes tau accumulation and toxicity in vivo.
実験動物マウス RBRC06334 Glial activation is moderated by sex in response to amyloidosis but not to tau pathology in mouse models of neurodegenerative diseases.
ショウジョウバエ Microtubule affinity-regulating kinase 4 with an Alzheimer's disease-related mutation promotes tau accumulation and exacerbates neurodegeneration.
実験動物マウス RBRC02192 Neuronal deficiency of p38α-MAPK ameliorates symptoms and pathology of APP or Tau-transgenic Alzheimer's mouse models.
線虫 tm1153 Constitutive XBP-1s-mediated activation of the endoplasmic reticulum unfolded protein response protects against pathological tau.
ショウジョウバエ DGRC#122076 Tau-Mediated Disruption of the Spliceosome Triggers Cryptic RNA Splicing and Neurodegeneration in Alzheimer's Disease.
ショウジョウバエ The Drosophila model system to study tau action.
ショウジョウバエ Mask mitigates MAPT- and FUS-induced degeneration by enhancing autophagy through lysosomal acidification.
ショウジョウバエ 8203R-1 Cdk5 increases MARK4 activity and augments pathological tau accumulation and toxicity through tau phosphorylation at Ser262.
ショウジョウバエ S6K/p70S6K1 protects against tau-mediated neurodegeneration by decreasing the level of tau phosphorylated at Ser262 in a Drosophila model of tauopathy.
ヒト・動物細胞 MDBK(RCB0180) A cell-based interferon-tau assay with an interferon-stimulated gene 15 promoter.
線虫 tm351 DOPA Decarboxylase Modulates Tau Toxicity.
実験動物マウス RBRC01390 Nrf2 mediates the expression of BAG3 and autophagy cargo adaptor proteins and tau clearance in an age-dependent manner.
ショウジョウバエ 7899R-2 , 8604R-1 , 8604R-2 , 3546R-1 , 8276R-2 , 8276R-3 , 1090R-1 , 1090R-2 , 10920R-2 , 10920R-3 , ... Functional screening of Alzheimer risk loci identifies PTK2B as an in vivo modulator and early marker of Tau pathology.
ヒト・動物細胞 PC-12(RCB0009) Combination of PKCε Activation and PTP1B Inhibition Effectively Suppresses Aβ-Induced GSK-3β Activation and Tau Phosphorylation.
ショウジョウバエ elav-GAL4 Nontoxic singlet oxygen generator as a therapeutic candidate for treating tauopathies.
実験動物マウス RBRC02370 Progranulin reduction is associated with increased tau phosphorylation in P301L tau transgenic mice.
実験動物マウス RBRC01390 Nrf2 reduces levels of phosphorylated tau protein by inducing autophagy adaptor protein NDP52.