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  • Search Condition : Filter (MeSH = tau Proteins / metabolism*)
Species Resource Title
Mice RBRC02370 Spreading of Alzheimer tau seeds is enhanced by aging and template matching with limited impact of amyloid-β.
Human and Animal Cells Atg5^(+/+)MEF(RCB2710) , Atg5^(-/-)MEF(RCB2711) Tau phosphorylation affects its axonal transport and degradation.
Drosophila Disulfide bond formation in microtubule-associated tau protein promotes tau accumulation and toxicity in vivo.
Mice RBRC06334 Glial activation is moderated by sex in response to amyloidosis but not to tau pathology in mouse models of neurodegenerative diseases.
Drosophila Microtubule affinity-regulating kinase 4 with an Alzheimer's disease-related mutation promotes tau accumulation and exacerbates neurodegeneration.
Mice RBRC02192 Neuronal deficiency of p38α-MAPK ameliorates symptoms and pathology of APP or Tau-transgenic Alzheimer's mouse models.
C.elegans tm1153 Constitutive XBP-1s-mediated activation of the endoplasmic reticulum unfolded protein response protects against pathological tau.
Drosophila DGRC#122076 Tau-Mediated Disruption of the Spliceosome Triggers Cryptic RNA Splicing and Neurodegeneration in Alzheimer's Disease.
Drosophila The Drosophila model system to study tau action.
Drosophila Mask mitigates MAPT- and FUS-induced degeneration by enhancing autophagy through lysosomal acidification.
Drosophila 8203R-1 Cdk5 increases MARK4 activity and augments pathological tau accumulation and toxicity through tau phosphorylation at Ser262.
Drosophila S6K/p70S6K1 protects against tau-mediated neurodegeneration by decreasing the level of tau phosphorylated at Ser262 in a Drosophila model of tauopathy.
Human and Animal Cells MDBK(RCB0180) A cell-based interferon-tau assay with an interferon-stimulated gene 15 promoter.
C.elegans tm351 DOPA Decarboxylase Modulates Tau Toxicity.
Mice RBRC01390 Nrf2 mediates the expression of BAG3 and autophagy cargo adaptor proteins and tau clearance in an age-dependent manner.
Drosophila 7899R-2 , 8604R-1 , 8604R-2 , 3546R-1 , 8276R-2 , 8276R-3 , 1090R-1 , 1090R-2 , 10920R-2 , 10920R-3 , ... Functional screening of Alzheimer risk loci identifies PTK2B as an in vivo modulator and early marker of Tau pathology.
Human and Animal Cells PC-12(RCB0009) Combination of PKCε Activation and PTP1B Inhibition Effectively Suppresses Aβ-Induced GSK-3β Activation and Tau Phosphorylation.
Drosophila elav-GAL4 Nontoxic singlet oxygen generator as a therapeutic candidate for treating tauopathies.
Mice RBRC02370 Progranulin reduction is associated with increased tau phosphorylation in P301L tau transgenic mice.
Mice RBRC01390 Nrf2 reduces levels of phosphorylated tau protein by inducing autophagy adaptor protein NDP52.