論文 - 詳細
| RRC ID | 1067 |
|---|---|
| 著者 | Hoshino Y, Mukai A, Yazawa K, Uno J, Ando A, Mikami Y, Fukai T, Ishikawa J, Yamaguchi K. |
| タイトル | Transvalencin A, a thiazolidine zinc complex antibiotic produced by a clinical isolate of Nocardia transvalensis. II. Structure elucidation. |
| ジャーナル | J Antibiot (Tokyo) |
| Abstract |
A novel antifungal antibiotic, transvalencin A, is produced by Nocardia transvalensis IFM 10065 isolated from a patient with actinomycotic mycetoma in Japan. The antibiotic structure was elucidated using NMR, mass spectrometric investigations, and X-ray crystallographic analysis. Transvalencin A is a 1:1 complex of a zinc and an organic acid with a phenolic substituent. Transvalencin A is comprised of o-substituted p-chlorophenol, tetrasubstituted oxazoline, disubstituted thiazolyl-N-methylthiazolidine and monosubstituted N-methylthiazolidine. |
| 巻・号 | 57(12) |
| ページ | 803-7 |
| 公開日 | 2004-12-1 |
| DOI | 10.7164/antibiotics.57.803 |
| PMID | 15745115 |
| MeSH | Anti-Bacterial Agents / chemistry* Magnetic Resonance Spectroscopy Mass Spectrometry Models, Molecular Molecular Structure Nocardia / chemistry* Organometallic Compounds / chemistry* Thiazoles / chemistry* Zinc / chemistry* |
| IF | 2.668 |
| 引用数 | 11 |
| WOS 分野 | PHARMACOLOGY & PHARMACY BIOTECHNOLOGY & APPLIED MICROBIOLOGY IMMUNOLOGY MICROBIOLOGY |
| オルトメトリクス指標 |
オルトメトリクス指標項目
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| 最多言及媒体 | Patent(IFI CLAIMS) |
| 各媒体での言及数の合計 | 2 |
| 過去6か月間でのオルトメトリクス指標の変動値 | 0.0 |
| リソース情報 | |
| 病原微生物 | IFM 10065 |