RRC ID 11634
Author Bradu A, Ma L, Bloor JW, Podoleanu A.
Title Dual optical coherence tomography/fluorescence microscopy for monitoring of Drosophila melanogaster larval heart.
Journal J Biophotonics
Abstract This article demonstrates a combined instrument of two imaging modalities to acquire information on cardiac function in larval Drosophila melanogaster: optical coherence tomography (OCT) and laser scanning fluorescence microscopy (LSFM). For this purpose, a dedicated imaging instrument able to sequentially provide cross-sectional OCT and C-scan LSFM images has been developed. With this dual-imaging system, the heart can be easily located and visualized within the specimen and the change of the heart shape in a cardiac cycle can be monitored.
Volume 2(6-7)
Pages 380-8
Published 2009-7-1
DOI 10.1002/jbio.200910021
PMID 19504517
MeSH Animals Drosophila melanogaster / anatomy & histology Drosophila melanogaster / growth & development Drosophila melanogaster / physiology* Female Fourier Analysis Gene Expression Regulation Heart / physiology* Larva / physiology Microfilament Proteins / metabolism Microscopy, Confocal / instrumentation Microscopy, Confocal / methods* Microscopy, Fluorescence / instrumentation Microscopy, Fluorescence / methods* Protein Transport Systems Integration Tomography, Optical Coherence / instrumentation Tomography, Optical Coherence / methods*
IF 3.032
Times Cited 34
WOS Category OPTICS BIOPHYSICS BIOCHEMICAL RESEARCH METHODS
Resource
Drosophila NP1029-Gal4 (DGRC#112459)