RRC ID |
11634
|
Author |
Bradu A, Ma L, Bloor JW, Podoleanu A.
|
Title |
Dual optical coherence tomography/fluorescence microscopy for monitoring of Drosophila melanogaster larval heart.
|
Journal |
J Biophotonics
|
Abstract |
This article demonstrates a combined instrument of two imaging modalities to acquire information on cardiac function in larval Drosophila melanogaster: optical coherence tomography (OCT) and laser scanning fluorescence microscopy (LSFM). For this purpose, a dedicated imaging instrument able to sequentially provide cross-sectional OCT and C-scan LSFM images has been developed. With this dual-imaging system, the heart can be easily located and visualized within the specimen and the change of the heart shape in a cardiac cycle can be monitored.
|
Volume |
2(6-7)
|
Pages |
380-8
|
Published |
2009-7-1
|
DOI |
10.1002/jbio.200910021
|
PMID |
19504517
|
MeSH |
Animals
Drosophila melanogaster / anatomy & histology
Drosophila melanogaster / growth & development
Drosophila melanogaster / physiology*
Female
Fourier Analysis
Gene Expression Regulation
Heart / physiology*
Larva / physiology
Microfilament Proteins / metabolism
Microscopy, Confocal / instrumentation
Microscopy, Confocal / methods*
Microscopy, Fluorescence / instrumentation
Microscopy, Fluorescence / methods*
Protein Transport
Systems Integration
Tomography, Optical Coherence / instrumentation
Tomography, Optical Coherence / methods*
|
IF |
3.032
|
Times Cited |
34
|
WOS Category
|
OPTICS
BIOPHYSICS
BIOCHEMICAL RESEARCH METHODS
|
Resource |
Drosophila |
NP1029-Gal4 (DGRC#112459) |