RRC ID 15378
Author Méndez-Lago M, Bergman CM, de Pablos B, Tracey A, Whitehead SL, Villasante A.
Title A large palindrome with interchromosomal gene duplications in the pericentromeric region of the D. melanogaster Y chromosome.
Journal Mol Biol Evol
Abstract The non-recombining Y chromosome is expected to degenerate over evolutionary time, however, gene gain is a common feature of Y chromosomes of mammals and Drosophila. Here, we report that a large palindrome containing interchromosomal segmental duplications is located in the vicinity of the first amplicon detected in the Y chromosome of D. melanogaster. The recent appearance of such amplicons suggests that duplications to the Y chromosome, followed by the amplification of the segmental duplications, are a mechanism for the continuing evolution of Drosophila Y chromosomes.
Volume 28(7)
Pages 1967-71
Published 2011-7-1
DOI 10.1093/molbev/msr034
PII msr034
PMID 21297157
PMC PMC4202384
MeSH Animals Drosophila melanogaster / genetics* Evolution, Molecular Gene Duplication* Genes, Insect* Inverted Repeat Sequences* Models, Genetic Molecular Sequence Data Y Chromosome*
IF 11.062
Times Cited 12
WOS Category GENETICS & HEREDITY BIOCHEMISTRY & MOLECULAR BIOLOGY EVOLUTIONARY BIOLOGY
Resource
INFORMATION
Drosophila Infomation of DME1-001M04 and DME1-007E02 (Drosophila BAC library)