RRC ID |
15616
|
著者 |
Nakato T, Tago R, Akiyama K, Maruyama M, Sugahara T, Kishida T, Yamauchi S.
|
タイトル |
Stereoselective construction of tetra-substituted tetrahydrofuran compounds from benzylic hemiacetal in the presence of H2 and a Pd catalyst: stereoselective synthesis of a stereoisomer of (-)-virgatusin and its antimicrobiological activity.
|
ジャーナル |
Biosci Biotechnol Biochem
|
Abstract |
Tetra-substituted tetrahydrofuran compounds were stereoselectively prepared from benzylic hemiacetal in the neutral condition by employing the simple reagent, H(2), and a Pd catalyst. The stereoselective conversion of benzylic hemiacetal to two different stereoisomers of the tetrasubstituted tetrahydrofuran compound was observed. One of these tetrahydrofuran compounds was converted to the virgatusin stereoisomer to estimate its antimicrobiological activity.
|
巻・号 |
72(1)
|
ページ |
197-203
|
公開日 |
2008-1-1
|
DOI |
10.1271/bbb.70554
|
PII |
JST.JSTAGE/bbb/70554
|
PMID |
18175922
|
MeSH |
Anti-Bacterial Agents / chemical synthesis*
Anti-Bacterial Agents / chemistry
Benzyl Compounds
Catalysis
Furans / chemical synthesis*
Furans / chemistry
Magnetic Resonance Spectroscopy
Models, Molecular
Optical Rotation
Polymers / chemistry
Solvents
|
IF |
1.516
|
引用数 |
6
|
WOS 分野
|
FOOD SCIENCE & TECHNOLOGY
CHEMISTRY, APPLIED
BIOTECHNOLOGY & APPLIED MICROBIOLOGY
BIOCHEMISTRY & MOLECULAR BIOLOGY
|
リソース情報 |
一般微生物 |
JCM 11481 |