論文 - 詳細
| RRC ID | 18189 |
|---|---|
| 著者 | Kawamoto S, Kaneoke M, Ohkouchi K, Amano Y, Takaoka Y, Kume K, Aki T, Yamashita S, Watanabe K, Kadowaki M, Hirata D, Ono K. |
| タイトル | Sake lees fermented with lactic acid bacteria prevents allergic rhinitis-like symptoms and IgE-mediated basophil degranulation. |
| ジャーナル | Biosci Biotechnol Biochem |
| Abstract |
We tested the effect of oral administration of fermented sake lees with lactic acid bacteria (FESLAB) on a murine model of allergic rhinitis upon immunization and nasal sensitization with ovalbumin (OVA). We used Lactobacillus paracasei NPSRIk-4 (isolated from sake lees), and L. brevis NPSRIv-8 (from fermented milk) as starter strains to produce the FESLAB. Oral FESLAB administration resulted in the development of significantly fewer sneezing symptoms than those seen in sham control animals given sterile water. We also found that FESLAB suppressed the allergen-induced degranulation of RBL2H3 rat basophilic leukemia cells. |
| 巻・号 | 75(1) |
| ページ | 140-4 |
| 公開日 | 2011-1-1 |
| DOI | 10.1271/bbb.100541 |
| PII | JST.JSTAGE/bbb/100541 |
| PMID | 21228477 |
| MeSH | Animals Basophils / cytology* Basophils / immunology Cell Degranulation* Cell Line, Tumor Dietary Supplements Female Fermentation* Hypersensitivity / complications Immunoglobulin E / immunology* Lactobacillus / metabolism* Mice Rats Rhinitis / complications Rhinitis / immunology Rhinitis / prevention & control* Wine* |
| IF | 1.516 |
| 引用数 | 17 |
| WOS 分野 | FOOD SCIENCE & TECHNOLOGY BIOTECHNOLOGY & APPLIED MICROBIOLOGY CHEMISTRY, APPLIED BIOCHEMISTRY & MOLECULAR BIOLOGY |
| リソース情報 | |
| ヒト・動物細胞 | RBL 2H3(RCB2782) |