論文 - 詳細
| RRC ID | 18589 |
|---|---|
| 著者 | Tagaya M, Yamazaki T, Tsuya D, Sugimoto Y, Hanagata N, Ikoma T. |
| タイトル | Nano/microstructural effect of hydroxyapatite nanocrystals on hepatocyte cell aggregation and adhesion. |
| ジャーナル | Macromol Biosci |
| Abstract |
Hepatocyte cell aggregation and adhesion to HAp nanocrystals covered with SU-8 polymer micropatterns by nano/microfabrication techniques is demonstrated. The surface roughness and wettability of the HAp nanocrystals are significantly different from those of the SU-8 polymer. QCM-D and microscopic observation clearly reveal that the cells realize the surface properties to form aggregation and preferentially adhere to the HAp nanocrystals at 2 h after seeding, indicating the importance of the microstructures as well as the interfacial phenomena at a nanometer scale. |
| 巻・号 | 11(11) |
| ページ | 1586-93 |
| 公開日 | 2011-11-10 |
| DOI | 10.1002/mabi.201100182 |
| PMID | 22052565 |
| MeSH | Biocompatible Materials / chemical synthesis* Biocompatible Materials / metabolism Biocompatible Materials / pharmacology Cell Adhesion Cell Aggregation Crystallography, X-Ray Durapatite / chemistry Durapatite / metabolism* Durapatite / pharmacology Epoxy Compounds / chemistry Hepatocytes / drug effects Hepatocytes / physiology* Humans Microscopy, Atomic Force Nanoparticles / chemistry Nanoparticles / ultrastructure Particle Size Photochemical Processes Surface Properties Tissue Engineering / methods* Tumor Cells, Cultured |
| IF | 3.416 |
| 引用数 | 13 |
| WOS 分野 | POLYMER SCIENCE BIOCHEMISTRY & MOLECULAR BIOLOGY MATERIALS SCIENCE, BIOMATERIALS |
| オルトメトリクス指標 |
オルトメトリクス指標項目
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| 最多言及媒体 | Patent(IFI CLAIMS) |
| 各媒体での言及数の合計 | 1 |
| 過去6か月間でのオルトメトリクス指標の変動値 | 0.0 |
| リソース情報 | |
| ヒト・動物細胞 | Hep G2 (RCB1648) |