RRC ID 27291
著者 Ando T, Nagase H, Eguchi K, Hirooka T, Nakamura T, Miyamoto K, Hirata K.
タイトル A novel method using cyanobacteria for ecotoxicity test of veterinary antimicrobial agents.
ジャーナル Environ Toxicol Chem
Abstract The effect of antimicrobial agents for veterinary use on the growth of cyanobacteria was investigated by measuring minimum inhibitory concentration, medium effective concentration (EC50), and no-observed-effect concentration of seven antimicrobial agents for eight cyanobacteria. The results demonstrated that the seven antimicrobial agents, even at low concentrations, inhibited the growth of cyanobacteria. Microcystis aeruginosa and Synechococcus sp. had the highest sensitivity to the antimicrobial agents used in the present study. It is considered that the utilization of cyanobacteria would enable easy and highly sensitive assessment of the toxicity of such chemicals as antimicrobial agents. We suggest that cyanobacteria be used for ecotoxicity test in addition to the hitherto established method that uses green algae.
巻・号 26(4)
ページ 601-6
公開日 2007-4-1
DOI 10.1897/06-195r.1
PMID 17447543
MeSH Anti-Infective Agents / toxicity* Cyanobacteria / drug effects* Cyanobacteria / growth & development Dose-Response Relationship, Drug Microbial Sensitivity Tests No-Observed-Adverse-Effect Level Toxicity Tests / methods* Veterinary Drugs / toxicity*
IF 3.152
引用数 55
WOS 分野 TOXICOLOGY ENVIRONMENTAL SCIENCES
リソース情報
藻類 NIES-19 NIES-44 NIES-107 NIES-23