Reference - Detail
| RRC ID | 28448 |
|---|---|
| Author | Inuzuka H, Miyatani S, Takeichi M. |
| Title | R-cadherin: a novel Ca(2+)-dependent cell-cell adhesion molecule expressed in the retina. |
| Journal | Neuron |
| Abstract |
cDNAs encoding a novel member of the cadherin cell adhesion receptor family were cloned. This cadherin is expressed in the retina of the chicken and is termed R-cadherin. It is similar to other cadherins in its primary structure, but most resembles N-cadherin, showing 74% amino acid identity. Cells expressing R-cadherin can adhere to those expressing N-cadherin when mixed, but they form homotypic clusters within their chimeric aggregates. In the development of the neural retina, R-cadherin begins to be expressed around embryonic day 8 in both neuronal and glial cells, and this expression continues up to the hatching stage. The pattern of the expression of R-cadherin was different from that of N-cadherin, suggesting distinctive roles in retinal morphogenesis. |
| Volume | 7(1) |
| Pages | 69-79 |
| Published | 1991-7-1 |
| DOI | 10.1016/0896-6273(91)90075-b |
| PII | 0896-6273(91)90075-B |
| PMID | 1712604 |
| MeSH | Amino Acid Sequence Animals Cadherins / genetics Cadherins / metabolism Cadherins / physiology* Cell Adhesion Molecules / metabolism Cell Adhesion Molecules / physiology* Chick Embryo DNA / metabolism Fluorescent Antibody Technique Molecular Sequence Data Retina / metabolism* Staining and Labeling |
| IF | 14.415 |
| Times Cited | 203 |
| WOS Category | NEUROSCIENCES |
| Altmetric score |
オルトメトリクス指標項目
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| The most frequently cited source | Patent(IFI CLAIMS) |
| Total number of mentions | 10 |
| Altmetric score changes over past 6months | 0.0 |
| Resource | |
| DNA material | Chicken R-cadherin full length cDNA (RDB01188). |